The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"SET domain
".
FunFam 51: Histone-lysine N-methyltransferase, H3 lysine-9 sp...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Histone methyltransferase activity GO:0042054
Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-histone. Histone methylation generally occurs on either an arginine or lysine residue.
|
4 | O82175 (/ISS) O82175 (/ISS) Q9C5P0 (/ISS) Q9C5P4 (/ISS) |
|
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
2 | Q9FF80 (/IDA) Q9FF80 (/IDA) |
|
Chromatin DNA binding GO:0031490
Interacting selectively and non-covalently with DNA that is assembled into chromatin.
|
2 | Q9FF80 (/IDA) Q9FF80 (/IDA) |
|
Histone methyltransferase activity GO:0042054
Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-histone. Histone methylation generally occurs on either an arginine or lysine residue.
|
2 | O82175 (/IDA) O82175 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q8VZ17 (/IPI) |
|
Methyltransferase activity GO:0008168
Catalysis of the transfer of a methyl group to an acceptor molecule.
|
1 | Q8VZ17 (/IDA) |
|
Methyl-CpG binding GO:0008327
Interacting selectively and non-covalently with a methylated cytosine/guanine dinucleotide.
|
1 | Q8VZ17 (/IDA) |
|
Methyl-CpNpG binding GO:0010428
Interacting selectively and non-covalently with a methylated cytosine/unspecified/guanine trinucleotide.
|
1 | Q8VZ17 (/IDA) |
|
Methyl-CpNpN binding GO:0010429
Interacting selectively and non-covalently with a methylated cytosine/unspecified/unspecified trinucleotide.
|
1 | Q8VZ17 (/IDA) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of gene expression, epigenetic GO:0040029
Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence.
|
6 | O82175 (/TAS) O82175 (/TAS) Q9C5P0 (/TAS) Q9C5P4 (/TAS) Q9FF80 (/TAS) Q9FF80 (/TAS) |
|
Histone methylation GO:0016571
The modification of histones by addition of methyl groups.
|
3 | O82175 (/IDA) O82175 (/IDA) Q8VZ17 (/IDA) |
|
Response to chitin GO:0010200
A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.
|
2 | O82175 (/IEP) O82175 (/IEP) |
|
Chromatin silencing by small RNA GO:0031048
Repression of transcription by conversion of large regions of DNA into heterochromatin, directed by small RNAs sharing sequence identity to the repressed region.
|
2 | O82175 (/IEP) O82175 (/IEP) |
|
Regulation of cell size GO:0008361
Any process that modulates the size of a cell.
|
1 | Q9C5P0 (/IMP) |
|
Leaf development GO:0048366
The process whose specific outcome is the progression of the leaf over time, from its formation to the mature structure.
|
1 | Q9C5P0 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | Q9C5P4 (/IDA) Q9FF80 (/IDA) Q9FF80 (/IDA) |
|
Chromosome GO:0005694
A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
|
1 | Q9C5P4 (/IDA) |
