The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
LCCL-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Cysteine-rich secretory protein LCCL domain-contai...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 O43405 (/IPI) O43405 (/IPI) O43405 (/IPI) O43405 (/IPI) Q62507 (/IPI)
Collagen binding GO:0005518
Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
4 O43405 (/IDA) O43405 (/IDA) O43405 (/IDA) O43405 (/IDA)
Collagen binding GO:0005518
Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
4 O42163 (/ISS) P84552 (/ISS) Q5EA64 (/ISS) Q62507 (/ISS)
Glycosaminoglycan binding GO:0005539
Interacting selectively and non-covalently with any glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues.
3 Q8BZQ2 (/IDA) Q8BZQ2 (/IDA) Q8VHI5 (/IDA)
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2 Q8BZQ2 (/IDA) Q8BZQ2 (/IDA)
Collagen binding GO:0005518
Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
1 Q62507 (/ISO)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Face morphogenesis GO:0060325
The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head.
10 F1QW68 (/IMP) F1QW68 (/IMP) Q9H0B8 (/IMP) Q9H0B8 (/IMP) Q9H0B8 (/IMP) Q9H0B8 (/IMP) Q9H0B8 (/IMP) Q9H0B8 (/IMP) Q9H336 (/IMP) Q9H336 (/IMP)
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
6 Q9H0B8 (/TAS) Q9H0B8 (/TAS) Q9H0B8 (/TAS) Q9H0B8 (/TAS) Q9H0B8 (/TAS) Q9H0B8 (/TAS)
Sensory perception of sound GO:0007605
The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
4 O43405 (/TAS) O43405 (/TAS) O43405 (/TAS) O43405 (/TAS)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
4 O43405 (/IMP) O43405 (/IMP) O43405 (/IMP) O43405 (/IMP)
Face morphogenesis GO:0060325
The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head.
4 Q8BZQ2 (/ISO) Q8BZQ2 (/ISO) Q8CGD2 (/ISO) Q8CGD2 (/ISO)
Extracellular matrix organization GO:0030198
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
3 Q8BZQ2 (/IDA) Q8BZQ2 (/IDA) Q8VHI5 (/IDA)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
2 Q5EA64 (/ISS) Q62507 (/ISS)
Spinal cord development GO:0021510
The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.
2 Q6UXI7 (/ISS) Q95LI2 (/ISS)
Lung development GO:0030324
The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.
2 G3V9T1 (/IEP) G3V9T1 (/IEP)
Embryonic viscerocranium morphogenesis GO:0048703
The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.
2 F1QW68 (/IMP) F1QW68 (/IMP)
Roof of mouth development GO:0060021
The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities.
2 F1QW68 (/IMP) F1QW68 (/IMP)
Cartilage morphogenesis GO:0060536
The process in which the anatomical structures of cartilage are generated and organized.
2 F1QW68 (/IMP) F1QW68 (/IMP)
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
1 F1Q7N1 (/IMP)
Sensory perception of sound GO:0007605
The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
1 Q62507 (/IMP)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
1 Q62507 (/ISO)
Positive regulation of cell-substrate adhesion GO:0010811
Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.
1 Q8VHI5 (/IDA)
Spinal cord development GO:0021510
The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.
1 Q8VHI5 (/IMP)

There are 11 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
8 Q9H0B8 (/HDA) Q9H0B8 (/HDA) Q9H0B8 (/HDA) Q9H0B8 (/HDA) Q9H0B8 (/HDA) Q9H0B8 (/HDA) Q9H336 (/HDA) Q9H336 (/HDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
6 Q9H0B8 (/TAS) Q9H0B8 (/TAS) Q9H0B8 (/TAS) Q9H0B8 (/TAS) Q9H0B8 (/TAS) Q9H0B8 (/TAS)
Transport vesicle GO:0030133
Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell.
6 Q9H0B8 (/IDA) Q9H0B8 (/IDA) Q9H0B8 (/IDA) Q9H0B8 (/IDA) Q9H0B8 (/IDA) Q9H0B8 (/IDA)
Secretory granule lumen GO:0034774
The volume enclosed by the membrane of a secretory granule.
6 Q9H0B8 (/TAS) Q9H0B8 (/TAS) Q9H0B8 (/TAS) Q9H0B8 (/TAS) Q9H0B8 (/TAS) Q9H0B8 (/TAS)
Ficolin-1-rich granule lumen GO:1904813
Any membrane-enclosed lumen that is part of a ficolin-1-rich granule.
6 Q9H0B8 (/TAS) Q9H0B8 (/TAS) Q9H0B8 (/TAS) Q9H0B8 (/TAS) Q9H0B8 (/TAS) Q9H0B8 (/TAS)
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
4 Q62507 (/IDA) Q8BZQ2 (/IDA) Q8BZQ2 (/IDA) Q8VHI5 (/IDA)
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
4 O43405 (/IDA) O43405 (/IDA) O43405 (/IDA) O43405 (/IDA)
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
3 O42163 (/ISS) P84552 (/ISS) Q5EA64 (/ISS)
Transport vesicle GO:0030133
Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell.
2 Q8BZQ2 (/ISO) Q8BZQ2 (/ISO)
Interstitial matrix GO:0005614
A type of extracellular matrix found in interstitial connective tissue, characterized by the presence of fibronectins, proteoglycans, and types I, III, V, VI, VII and XII collagens.
1 Q8VHI5 (/IDA)
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
1 Q62507 (/ISO)
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