The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"YVTN repeat-like/Quinoprotein amine dehydrogenase
".
FunFam 21: histone-binding protein RBBP4 isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 13 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
128 |
P90916 (/IPI)
Q09028 (/IPI)
Q09028 (/IPI)
Q09028 (/IPI)
Q09028 (/IPI)
Q09028 (/IPI)
Q09028 (/IPI)
Q09028 (/IPI)
Q09028 (/IPI)
Q09028 (/IPI)
(118 more) |
|
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
|
52 |
P90916 (/IPI)
Q09028 (/IPI)
Q09028 (/IPI)
Q09028 (/IPI)
Q09028 (/IPI)
Q09028 (/IPI)
Q09028 (/IPI)
Q09028 (/IPI)
Q09028 (/IPI)
Q09028 (/IPI)
(42 more) |
|
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
|
51 |
Q60972 (/IDA)
Q60972 (/IDA)
Q60972 (/IDA)
Q60972 (/IDA)
Q60972 (/IDA)
Q60972 (/IDA)
Q60972 (/IDA)
Q60972 (/IDA)
Q60972 (/IDA)
Q60972 (/IDA)
(41 more) |
|
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
|
51 |
Q09028 (/NAS)
Q09028 (/NAS)
Q09028 (/NAS)
Q09028 (/NAS)
Q09028 (/NAS)
Q09028 (/NAS)
Q09028 (/NAS)
Q09028 (/NAS)
Q09028 (/NAS)
Q09028 (/NAS)
(41 more) |
|
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
|
51 |
Q60972 (/ISO)
Q60972 (/ISO)
Q60972 (/ISO)
Q60972 (/ISO)
Q60972 (/ISO)
Q60972 (/ISO)
Q60972 (/ISO)
Q60972 (/ISO)
Q60972 (/ISO)
Q60972 (/ISO)
(41 more) |
|
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
|
6 | Q24572 (/ISS) Q24572 (/ISS) Q24572 (/ISS) Q24572 (/ISS) Q61Y48 (/ISS) Q61Y48 (/ISS) |
|
Histone acetyltransferase binding GO:0035035
Interacting selectively and non-covalently with the enzyme histone acetyltransferase.
|
4 | Q24572 (/ISS) Q24572 (/ISS) Q24572 (/ISS) Q24572 (/ISS) |
|
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
|
4 | Q24572 (/IDA) Q24572 (/IDA) Q24572 (/IDA) Q24572 (/IDA) |
|
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
|
4 | Q24572 (/TAS) Q24572 (/TAS) Q24572 (/TAS) Q24572 (/TAS) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
4 | Q24572 (/IPI) Q24572 (/IPI) Q24572 (/IPI) Q24572 (/IPI) |
Showing 1 to 10 of 13 entries
There are 57 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chromatin assembly GO:0031497
The assembly of DNA, histone proteins, other associated proteins, and sometimes RNA, into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus.
|
113 |
O93377 (/ISS)
Q24572 (/ISS)
Q24572 (/ISS)
Q24572 (/ISS)
Q24572 (/ISS)
Q3MHL3 (/ISS)
Q3MHL3 (/ISS)
Q3MHL3 (/ISS)
Q3MHL3 (/ISS)
Q3MHL3 (/ISS)
(103 more) |
|
CENP-A containing nucleosome assembly GO:0034080
The formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres.
|
71 |
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
(61 more) |
|
Negative regulation of gene expression, epigenetic GO:0045814
Any epigenetic process that stops, prevents or reduces the rate of gene expression.
|
71 |
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
(61 more) |
|
Negative regulation of G0 to G1 transition GO:0070317
A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase.
|
71 |
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
(61 more) |
|
Regulation of signal transduction by p53 class mediator GO:1901796
Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator.
|
71 |
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
(61 more) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
55 |
Q60972 (/ISS)
Q60972 (/ISS)
Q60972 (/ISS)
Q60972 (/ISS)
Q60972 (/ISS)
Q60972 (/ISS)
Q60972 (/ISS)
Q60972 (/ISS)
Q60972 (/ISS)
Q60972 (/ISS)
(45 more) |
|
Chromatin assembly GO:0031497
The assembly of DNA, histone proteins, other associated proteins, and sometimes RNA, into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus.
|
55 |
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
(45 more) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
52 |
Q60972 (/TAS)
Q60972 (/TAS)
Q60972 (/TAS)
Q60972 (/TAS)
Q60972 (/TAS)
Q60972 (/TAS)
Q60972 (/TAS)
Q60972 (/TAS)
Q60972 (/TAS)
Q60972 (/TAS)
(42 more) |
|
DNA replication-dependent nucleosome assembly GO:0006335
The formation of nucleosomes on newly replicated DNA, coupled to strand elongation.
|
51 |
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
(41 more) |
|
DNA replication-dependent nucleosome assembly GO:0006335
The formation of nucleosomes on newly replicated DNA, coupled to strand elongation.
|
51 |
Q60972 (/ISO)
Q60972 (/ISO)
Q60972 (/ISO)
Q60972 (/ISO)
Q60972 (/ISO)
Q60972 (/ISO)
Q60972 (/ISO)
Q60972 (/ISO)
Q60972 (/ISO)
Q60972 (/ISO)
(41 more) |
Showing 1 to 10 of 57 entries
There are 39 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
199 |
B5DFB2 (/IDA)
B5DFB2 (/IDA)
B5DFB2 (/IDA)
B5DFB2 (/IDA)
B5DFB2 (/IDA)
B5DFB2 (/IDA)
B5DFB2 (/IDA)
B5DFB2 (/IDA)
B5DFB2 (/IDA)
B5DFB2 (/IDA)
(189 more) |
|
NuRD complex GO:0016581
An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins.
|
127 |
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
(117 more) |
|
ESC/E(Z) complex GO:0035098
A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4.
|
126 |
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
(116 more) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
123 |
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
Q09028 (/TAS)
(113 more) |
|
CAF-1 complex GO:0033186
A conserved heterotrimeric protein complex that promotes histone H3 and H4 deposition onto newly synthesized DNA during replication or DNA repair; specifically facilitates replication-dependent nucleosome assembly with the major histone H3 (H3.1). In many species the CAF-1 subunits are designated p150, p60, and p48.
|
109 |
O93377 (/ISS)
Q3MHL3 (/ISS)
Q3MHL3 (/ISS)
Q3MHL3 (/ISS)
Q3MHL3 (/ISS)
Q3MHL3 (/ISS)
Q3MHL3 (/ISS)
Q3MHL3 (/ISS)
Q3MHL3 (/ISS)
Q3MHL3 (/ISS)
(99 more) |
|
ESC/E(Z) complex GO:0035098
A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4.
|
107 |
O93377 (/ISS)
Q3MHL3 (/ISS)
Q3MHL3 (/ISS)
Q3MHL3 (/ISS)
Q3MHL3 (/ISS)
Q3MHL3 (/ISS)
Q3MHL3 (/ISS)
Q3MHL3 (/ISS)
Q3MHL3 (/ISS)
Q3MHL3 (/ISS)
(97 more) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
93 |
E9PC52 (/IDA)
E9PC52 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
(83 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
93 |
E9PC52 (/IDA)
E9PC52 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
(83 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
58 |
Q60972 (/ISS)
Q60972 (/ISS)
Q60972 (/ISS)
Q60972 (/ISS)
Q60972 (/ISS)
Q60972 (/ISS)
Q60972 (/ISS)
Q60972 (/ISS)
Q60972 (/ISS)
Q60972 (/ISS)
(48 more) |
|
NURF complex GO:0016589
An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2L in mammals), a NURF301 homolog (BPTF in humans), and additional subunits, though the composition of these additional subunits varies slightly with species. NURF is involved in regulation of transcription from TRNA polymerase II promoters.
|
55 |
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
Q09028 (/IDA)
(45 more) |
Showing 1 to 10 of 39 entries
