The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Rieske [2Fe-2S] iron-sulphur domain
".
FunFam 12: 3-ketosteroid-9-alpha-hydroxylase oxygenase subuni...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
|
13 |
B6V6V5 (/IDA)
F1CMX0 (/IDA)
F1CMY8 (/IDA)
P71875 (/IDA)
P71875 (/IDA)
P71875 (/IDA)
P71875 (/IDA)
P71875 (/IDA)
P71875 (/IDA)
P71875 (/IDA)
(3 more) |
|
3-ketosteroid 9-alpha-monooxygenase activity GO:0036200
Catalysis of the reaction: androsta-1,4-diene-3,17-dione + NADH + H+ + O2 = 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + NAD+ + H2O.
|
13 |
B6V6V5 (/IDA)
F1CMX0 (/IDA)
F1CMY8 (/IDA)
P71875 (/IDA)
P71875 (/IDA)
P71875 (/IDA)
P71875 (/IDA)
P71875 (/IDA)
P71875 (/IDA)
P71875 (/IDA)
(3 more) |
|
2 iron, 2 sulfur cluster binding GO:0051537
Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
|
13 |
B6V6V5 (/IDA)
F1CMX0 (/IDA)
F1CMY8 (/IDA)
P71875 (/IDA)
P71875 (/IDA)
P71875 (/IDA)
P71875 (/IDA)
P71875 (/IDA)
P71875 (/IDA)
P71875 (/IDA)
(3 more) |
|
Ketosteroid monooxygenase activity GO:0047086
Catalysis of the reaction: O2 + NADPH + progesterone = H2O + NADP+ + testosterone acetate.
|
10 | P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) |
|
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
|
4 | F1CMX6 (/ISS) F1CMX8 (/ISS) F1CMX8 (/ISS) F1CMX8 (/ISS) |
|
Steroid 9-alpha-monooxygenase activity GO:0050292
Catalysis of the reaction: AH(2) + O(2) + pregna-4,9(11)-diene-3,20-dione = 9,11alpha-epoxypregn-4-ene-3,20-dione + A + H(2)O.
|
3 | A0R4R3 (/IMP) A0R4R3 (/IMP) A0R4R3 (/IMP) |
|
3-ketosteroid 9-alpha-monooxygenase activity GO:0036200
Catalysis of the reaction: androsta-1,4-diene-3,17-dione + NADH + H+ + O2 = 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + NAD+ + H2O.
|
1 | F1CMY8 (/NAS) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cholesterol catabolic process GO:0006707
The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
|
10 | P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) |
|
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
|
10 | P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) P71875 (/IDA) |
|
Protein homotrimerization GO:0070207
The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.
|
10 | P71875 (/IPI) P71875 (/IPI) P71875 (/IPI) P71875 (/IPI) P71875 (/IPI) P71875 (/IPI) P71875 (/IPI) P71875 (/IPI) P71875 (/IPI) P71875 (/IPI) |
|
Response to cholesterol GO:0070723
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.
|
10 | P71875 (/IEP) P71875 (/IEP) P71875 (/IEP) P71875 (/IEP) P71875 (/IEP) P71875 (/IEP) P71875 (/IEP) P71875 (/IEP) P71875 (/IEP) P71875 (/IEP) |
|
Steroid biosynthetic process GO:0006694
The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.
|
3 | A0R4R3 (/IMP) A0R4R3 (/IMP) A0R4R3 (/IMP) |
|
Cholesterol catabolic process GO:0006707
The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
|
1 | F1CMY8 (/NAS) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
