The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Laminin
".
FunFam 66: FAT atypical cadherin 4
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 12 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | O88516 (/IPI) P10040 (/IPI) P18168 (/IPI) Q2PZL6 (/IPI) Q5GFL6 (/IPI) Q6V0I7 (/IPI) |
|
Notch binding GO:0005112
Interacting selectively and non-covalently with the Notch (N) protein, a surface receptor.
|
3 | O88516 (/NAS) P18168 (/NAS) Q9NYJ7 (/NAS) |
|
Notch binding GO:0005112
Interacting selectively and non-covalently with the Notch (N) protein, a surface receptor.
|
2 | O88671 (/IPI) P18168 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | Q5GFL6 (/IDA) Q70UZ7 (/IDA) |
|
Protein kinase C binding GO:0005080
Interacting selectively and non-covalently with protein kinase C.
|
1 | P10040 (/IPI) |
|
Notch binding GO:0005112
Interacting selectively and non-covalently with the Notch (N) protein, a surface receptor.
|
1 | P18168 (/IDA) |
|
Notch binding GO:0005112
Interacting selectively and non-covalently with the Notch (N) protein, a surface receptor.
|
1 | O88516 (/ISO) |
|
Notch binding GO:0005112
Interacting selectively and non-covalently with the Notch (N) protein, a surface receptor.
|
1 | O88671 (/TAS) |
|
Spectrin binding GO:0030507
Interacting selectively and non-covalently with spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers.
|
1 | P10040 (/TAS) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q70UZ7 (/ISO) |
|
Glycosphingolipid binding GO:0043208
Interacting selectively and non-covalently with glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.
|
1 | P18168 (/IDA) |
|
Receptor ligand activity GO:0048018
The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same, or different, cell that expresses the receptor. Ligands may diffuse extracellularly from their point of origin to the receiving cell, or remain attached to an adjacent cell surface (e.g. Notch ligands).
|
1 | P18168 (/IDA) |
There are 117 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Establishment or maintenance of epithelial cell apical/basal polarity GO:0045197
Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell.
|
4 | A0A2R8QCM5 (/IGI) B3DJP2 (/IGI) Q1A5L3 (/IGI) Q1L927 (/IGI) |
|
Photoreceptor cell maintenance GO:0045494
Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light.
|
3 | B8JI71 (/IMP) B8JI71 (/IMP) P10040 (/IMP) |
|
Skeletal system development GO:0001501
The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).
|
2 | O88516 (/IMP) Q9NYJ7 (/IMP) |
|
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
|
2 | B8JI71 (/IMP) B8JI71 (/IMP) |
|
Notch signaling pathway GO:0007219
A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
2 | P18168 (/IMP) Q2PZL6 (/IMP) |
|
Salivary gland morphogenesis GO:0007435
The process in which the anatomical structures of the salivary gland are generated and organized.
|
2 | P10040 (/IMP) P18168 (/IMP) |
|
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
|
2 | B8JI71 (/IMP) B8JI71 (/IMP) |
|
Epithelial structure maintenance GO:0010669
A tissue homeostatic process required for the maintenance of epithelial structure.
|
2 | D2DUP9 (/IGI) U3JA51 (/IGI) |
|
Photoreceptor cell outer segment organization GO:0035845
A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials.
|
2 | B8JI71 (/IMP) B8JI71 (/IMP) |
|
Retinal cone cell development GO:0046549
Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision.
|
2 | B8JI71 (/IMP) B8JI71 (/IMP) |
|
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
2 | Q5GFL6 (/IDA) Q70UZ7 (/IDA) |
|
Skeletal system development GO:0001501
The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).
|
1 | O88516 (/ISO) |
|
Skeletal system development GO:0001501
The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).
|
1 | O88671 (/ISS) |
|
Branching involved in ureteric bud morphogenesis GO:0001658
The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.
|
1 | Q2PZL6 (/IMP) |
|
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
|
1 | O88516 (/NAS) |
|
Cell fate determination GO:0001709
A process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.
|
1 | O88516 (/NAS) |
|
Cell fate determination GO:0001709
A process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.
|
1 | O88671 (/TAS) |
|
Establishment of planar polarity GO:0001736
Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.
|
1 | Q2PZL6 (/IC) |
|
Compound eye morphogenesis GO:0001745
The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
|
1 | P10040 (/IGI) |
|
Compound eye morphogenesis GO:0001745
The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
|
1 | P10040 (/IMP) |
|
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
|
1 | O88516 (/IDA) |
|
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
|
1 | O88516 (/IMP) |
|
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
|
1 | Q2PZL6 (/IMP) |
|
Heart morphogenesis GO:0003007
The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
1 | Q2PZL6 (/IMP) |
|
Apical constriction GO:0003383
The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell.
|
1 | P10040 (/IMP) |
|
Plasma membrane organization GO:0007009
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane.
|
1 | Q2PZL6 (/IMP) |
|
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157
The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.
|
1 | Q2PZL6 (/IDA) |
|
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157
The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.
|
1 | Q6V0I7 (/ISS) |
|
Calcium-independent cell-matrix adhesion GO:0007161
The binding of a cell to the extracellular matrix via adhesion molecules that do not require the presence of calcium for the interaction.
|
1 | Q70UZ7 (/IDA) |
|
Calcium-independent cell-matrix adhesion GO:0007161
The binding of a cell to the extracellular matrix via adhesion molecules that do not require the presence of calcium for the interaction.
|
1 | Q70UZ7 (/IGI) |
|
Establishment or maintenance of cell polarity GO:0007163
Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
|
1 | P10040 (/IMP) |
|
Notch signaling pathway GO:0007219
A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | P18168 (/IGI) |
|
Notch signaling pathway GO:0007219
A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | O88516 (/NAS) |
|
Compartment pattern specification GO:0007386
The regionalization process in which embryonic segments are divided into compartments that will result in differences in cell differentiation.
|
1 | O88516 (/IMP) |
|
Dorsal closure GO:0007391
The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
|
1 | P10040 (/IMP) |
|
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
1 | P10040 (/IMP) |
|
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
1 | O88516 (/NAS) |
|
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
|
1 | O88671 (/IEP) |
|
Sensory organ development GO:0007423
The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure.
|
1 | P18168 (/IMP) |
|
Open tracheal system development GO:0007424
The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster.
|
1 | P10040 (/IMP) |
|
Larval salivary gland morphogenesis GO:0007436
The process, occurring in the larva, by which the anatomical structures of the salivary gland are generated and organized.
|
1 | P18168 (/IMP) |
|
Malpighian tubule morphogenesis GO:0007443
The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.
|
1 | P10040 (/IMP) |
|
Imaginal disc-derived wing morphogenesis GO:0007476
The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.
|
1 | P18168 (/IMP) |
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
1 | P10040 (/IMP) |
|
Fibroblast growth factor receptor signaling pathway GO:0008543
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.
|
1 | Q2PZL6 (/IMP) |
|
Imaginal disc-derived wing margin morphogenesis GO:0008587
The process in which the anatomical structures of the imaginal disc-derived wing margin are generated and organized. The wing margin is a strip of cells in the third instar disc at the boundary between the presumptive dorsal and ventral surfaces of the wing blade.
|
1 | P18168 (/IMP) |
|
Tissue development GO:0009888
The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.
|
1 | O88516 (/IDA) |
|
Glial cell proliferation GO:0014009
The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others.
|
1 | P18168 (/IMP) |
|
Second mitotic wave involved in compound eye morphogenesis GO:0016330
A discrete cell cycle in the third instar eye imaginal disc after progression of the morphogenetic furrow that contributes to compound eye morphogenesis. It is essential for generation of a sufficient pool of uncommitted cells to develop complete ommatidia.
|
1 | P18168 (/IMP) |
|
Establishment or maintenance of polarity of embryonic epithelium GO:0016332
Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization of epithelial cells in an embryo.
|
1 | P10040 (/IMP) |
|
Establishment or maintenance of polarity of follicular epithelium GO:0016334
Any cellular process that results in the specification, formation or maintenance of a polarized follicular epithelial sheet.
|
1 | P10040 (/IMP) |
|
Cerebral cortex development GO:0021987
The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon.
|
1 | Q2PZL6 (/IMP) |
|
Cerebral cortex development GO:0021987
The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon.
|
1 | Q6V0I7 (/ISS) |
|
Neurogenesis GO:0022008
Generation of cells within the nervous system.
|
1 | Q2PZL6 (/IMP) |
|
Neurogenesis GO:0022008
Generation of cells within the nervous system.
|
1 | Q6V0I7 (/ISS) |
|
Germ-line stem cell population maintenance GO:0030718
Any process by which an organism or tissue maintains a population of germ-line stem cells.
|
1 | P18168 (/IGI) |
|
Negative regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032435
Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
1 | P10040 (/IGI) |
|
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
|
1 | P10040 (/IMP) |
|
Regulation of intracellular protein transport GO:0033157
Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells.
|
1 | P10040 (/IMP) |
|
Adherens junction organization GO:0034332
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments.
|
1 | P10040 (/IMP) |
|
Liquid clearance, open tracheal system GO:0035002
The clearance of liquid from the epithelial tubes of an open tracheal system, shortly before the emergence of the larva, to generate an air-filled tubule system.
|
1 | P10040 (/IGI) |
|
Cuticle pattern formation GO:0035017
The regionalization process that gives rise to the patterns of cell differentiation in the cuticle.
|
1 | P18168 (/IMP) |
|
Establishment or maintenance of apical/basal cell polarity GO:0035088
Any cellular process that results in the specification, formation or maintenance polarization of a cell's architecture along its apical/basal axis so that the apical and basal regions of the cell have different membrane, extracellular matrix and sub-membrane cellular components.
|
1 | P10040 (/IMP) |
|
Maintenance of apical/basal cell polarity GO:0035090
Retaining the established polarization of a cell along its apical/basal axis.
|
1 | P10040 (/IMP) |
|
Larval lymph gland hemopoiesis GO:0035167
The production of blood cells from the larval lymph gland. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages.
|
1 | P18168 (/IEP) |
|
Negative regulation of lamellocyte differentiation GO:0035204
Any process that stops, prevents, or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.
|
1 | P18168 (/IMP) |
|
Eye-antennal disc development GO:0035214
Progression of the eye-antennal imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the eye, antenna, head capsule and maxillary palps.
|
1 | P18168 (/IMP) |
|
Tube morphogenesis GO:0035239
The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.
|
1 | P10040 (/IMP) |
|
Hippo signaling GO:0035329
The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1.
|
1 | Q2PZL6 (/IMP) |
|
Hippo signaling GO:0035329
The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1.
|
1 | Q6V0I7 (/ISS) |
|
Positive regulation of hippo signaling GO:0035332
Any process that activates or increases the frequency, rate or extent of hippo signaling.
|
1 | P10040 (/IGI) |
|
Positive regulation of hippo signaling GO:0035332
Any process that activates or increases the frequency, rate or extent of hippo signaling.
|
1 | P10040 (/IMP) |
|
Imaginal disc-derived leg segmentation GO:0036011
Division of an imaginal disc-derived leg into a series of semi-repetitive parts or segments. The Drosophila leg, for example, has nine segments, each separated from the next by a flexible joint.
|
1 | P18168 (/IMP) |
|
Compound eye photoreceptor development GO:0042051
The process whose specific outcome is the progression of a light-responsive receptor in the compound eye over time, from its formation to the mature structure.
|
1 | P10040 (/IMP) |
|
Rhabdomere development GO:0042052
The assembly and arrangement of a rhabdomere within a cell. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments.
|
1 | P10040 (/IMP) |
|
Crystal cell differentiation GO:0042688
The process in which a hemocyte precursor cell acquires the characteristics of a crystal cell, a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.
|
1 | P18168 (/IMP) |
|
Skeletal muscle tissue regeneration GO:0043403
The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.
|
1 | Q5T1H1 (/IMP) |
|
Ossification involved in bone maturation GO:0043931
The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state.
|
1 | Q2PZL6 (/IMP) |
|
Apical protein localization GO:0045176
Any process in which a protein is transported to, or maintained in, apical regions of the cell.
|
1 | P10040 (/IMP) |
|
Apical protein localization GO:0045176
Any process in which a protein is transported to, or maintained in, apical regions of the cell.
|
1 | P10040 (/IPI) |
|
Zonula adherens assembly GO:0045186
Assembly of the zonula adherens, a cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.
|
1 | P10040 (/IMP) |
|
Zonula adherens maintenance GO:0045218
Maintaining the zonula adherens junction, the cell-cell adherens junction formed near the apex of epithelial cells.
|
1 | P10040 (/IMP) |
|
Regulation of imaginal disc growth GO:0045570
Any process that modulates the frequency, rate or extent of the growth of the imaginal disc.
|
1 | P10040 (/IMP) |
|
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
|
1 | O88671 (/IDA) |
|
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
|
1 | P10040 (/IGI) |
|
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
|
1 | O88516 (/ISO) |
|
Lateral inhibition GO:0046331
Signaling between cells of equivalent developmental potential that results in these cells adopting different developmental fates. An example is the suppression by cells with a particular fate of the adoption of the same fate by surrounding cells.
|
1 | P18168 (/IMP) |
|
Negative regulation of organ growth GO:0046621
Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.
|
1 | P10040 (/IMP) |
|
Regulation of insulin receptor signaling pathway GO:0046626
Any process that modulates the frequency, rate or extent of insulin receptor signaling.
|
1 | Q5GFL6 (/IMP) |
|
Regulation of insulin receptor signaling pathway GO:0046626
Any process that modulates the frequency, rate or extent of insulin receptor signaling.
|
1 | Q70UZ7 (/ISO) |
|
Dorsal closure, amnioserosa morphology change GO:0046664
The changes that occur during dorsal closure of the shape and structure of the amnioserosa, an epithelium that occupies the dorsal side of the embryo.
|
1 | P10040 (/IMP) |
|
Amnioserosa maintenance GO:0046665
Maintenance of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis.
|
1 | P10040 (/IMP) |
|
Wing disc anterior/posterior pattern formation GO:0048100
The establishment, maintenance and elaboration of the anterior/posterior axis of the wing disc, a precursor to the wing.
|
1 | P18168 (/IMP) |
|
Wing disc dorsal/ventral pattern formation GO:0048190
The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing.
|
1 | P10040 (/IMP) |
|
Paraxial mesoderm development GO:0048339
The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube.
|
1 | O88516 (/IMP) |
|
Digestive tract development GO:0048565
The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed.
|
1 | Q2PZL6 (/IMP) |
|
Negative regulation of astrocyte differentiation GO:0048712
Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation.
|
1 | O88671 (/IDA) |
|
Negative regulation of astrocyte differentiation GO:0048712
Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation.
|
1 | O88516 (/ISO) |
|
Compound eye development GO:0048749
The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.
|
1 | P18168 (/IMP) |
|
Negative regulation of neurogenesis GO:0050768
Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.
|
1 | O88516 (/IDA) |
|
Positive regulation of neurogenesis GO:0050769
Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.
|
1 | O88671 (/IDA) |
|
Positive regulation of neurogenesis GO:0050769
Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.
|
1 | O88516 (/ISO) |
|
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
|
1 | P10040 (/IMP) |
|
Detection of light stimulus involved in visual perception GO:0050908
The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal.
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1 | Q5T1H1 (/IMP) |
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Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
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1 | Q70UZ7 (/ISO) |
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Centrosome localization GO:0051642
Any process in which a centrosome is transported to, and/or maintained in, a specific location within the cell.
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1 | P10040 (/IMP) |
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Inner ear receptor cell stereocilium organization GO:0060122
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of inner ear receptor cells.
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1 | Q2PZL6 (/IMP) |
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Trachea development GO:0060438
The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches.
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1 | P10040 (/IGI) |
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Membrane organization GO:0061024
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
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1 | P10040 (/IMP) |
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Cell morphogenesis involved in Malpighian tubule morphogenesis GO:0061336
The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule.
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1 | P10040 (/IMP) |
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Rhabdomere morphogenesis GO:0061541
The process in which the anatomical structures of a rhabdomere are generated and organized. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments.
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1 | P10040 (/IMP) |
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Nephron development GO:0072006
The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.
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1 | Q2PZL6 (/IMP) |
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Condensed mesenchymal cell proliferation GO:0072137
The multiplication or reproduction of cells, resulting in the expansion of a condensed mesenchymal cell population. A condensed mesenchymal cell population is a population of adherent mesenchymal cells.
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1 | Q2PZL6 (/IGI) |
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Condensed mesenchymal cell proliferation GO:0072137
The multiplication or reproduction of cells, resulting in the expansion of a condensed mesenchymal cell population. A condensed mesenchymal cell population is a population of adherent mesenchymal cells.
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1 | Q2PZL6 (/IMP) |
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Regulation of metanephric nephron tubule epithelial cell differentiation GO:0072307
Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation.
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1 | Q2PZL6 (/IMP) |
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Nuclear chromosome segregation GO:0098813
The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
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1 | P10040 (/IMP) |
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Assembly of apicomedial cortex actomyosin GO:0106036
A process which results in the assembly or arrangement of constituent parts apicomedial cortex actomyosin.
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1 | P10040 (/IMP) |
There are 20 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
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4 | A0A2R8QCM5 (/IPI) B3DJP2 (/IPI) Q1A5L3 (/IPI) Q1L927 (/IPI) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
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3 | Q5GFL6 (/HDA) Q5T1H1 (/HDA) Q6V0I7 (/HDA) |
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Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
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2 | Q5GFL6 (/IDA) Q70UZ7 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | P10040 (/IDA) P18168 (/IDA) |
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Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
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2 | P10040 (/IDA) P18168 (/IDA) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
1 | Q70UZ7 (/IDA) |
|
Basement membrane GO:0005604
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
|
1 | Q70UZ7 (/IDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q70UZ7 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P10040 (/HDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | P10040 (/HDA) |
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Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | P18168 (/TAS) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | P18168 (/IDA) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q9NYJ7 (/NAS) |
|
Rhabdomere GO:0016028
The specialized microvilli-containing organelle on the apical surfaces of a photoreceptor cell containing the visual pigment rhodopsin and most of the proteins involved in phototransduction.
|
1 | P10040 (/IDA) |
|
Apicolateral plasma membrane GO:0016327
The apical end of the lateral plasma membrane of epithelial cells.
|
1 | P10040 (/IDA) |
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Apicolateral plasma membrane GO:0016327
The apical end of the lateral plasma membrane of epithelial cells.
|
1 | P10040 (/IPI) |
|
Axolemma GO:0030673
The portion of the plasma membrane surrounding an axon; it is a specialized trilaminar random mosaic of protein molecules floating within a fluid matrix of highly mobile phospholipid molecules, 7-8 nm in thickness.
|
1 | P18168 (/IDA) |
|
Subapical complex GO:0035003
The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells.
|
1 | P10040 (/TAS) |
|
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
|
1 | Q2PZL6 (/IDA) |
|
Apical cortex GO:0045179
The region that lies just beneath the plasma membrane on the apical edge of a cell.
|
1 | P18168 (/IDA) |
