The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Laminin
".
FunFam 54: Slit guidance ligand 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 32 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | O88279 (/IPI) O94813 (/IPI) P31695 (/IPI) Q99466 (/IPI) Q99466 (/IPI) Q9DE36 (/IPI) Q9R1B9 (/IPI) |
Roundabout binding GO:0048495
Interacting selectively and non-covalently with the Roundabout (ROBO) receptor, a transmembrane receptor.
|
4 | O75093 (/IPI) O75094 (/IPI) O94813 (/IPI) Q80TR4 (/IPI) |
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
3 | Q80TR4 (/TAS) Q9R1B9 (/TAS) Q9WVB4 (/TAS) |
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
3 | O75093 (/NAS) O75094 (/NAS) O94813 (/NAS) |
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
|
3 | Q6MG89 (/TAS) Q99466 (/TAS) Q99466 (/TAS) |
Roundabout binding GO:0048495
Interacting selectively and non-covalently with the Roundabout (ROBO) receptor, a transmembrane receptor.
|
3 | Q80TR4 (/ISO) Q9R1B9 (/ISO) Q9WVB4 (/ISO) |
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
2 | Q99466 (/TAS) Q99466 (/TAS) |
Heparan sulfate proteoglycan binding GO:0043395
Interacting selectively and non-covalently with a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit.
|
2 | Q80TR4 (/ISO) Q9R1B9 (/ISO) |
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
2 | Q99466 (/TAS) Q99466 (/TAS) |
Roundabout binding GO:0048495
Interacting selectively and non-covalently with the Roundabout (ROBO) receptor, a transmembrane receptor.
|
2 | Q90Z43 (/ISA) Q90Z44 (/ISA) |
GTPase inhibitor activity GO:0005095
Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of GTP to GDP and orthophosphate.
|
1 | O94813 (/IDA) |
GTPase inhibitor activity GO:0005095
Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of GTP to GDP and orthophosphate.
|
1 | Q90Z44 (/ISA) |
GTPase inhibitor activity GO:0005095
Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of GTP to GDP and orthophosphate.
|
1 | Q9R1B9 (/ISO) |
Notch binding GO:0005112
Interacting selectively and non-covalently with the Notch (N) protein, a surface receptor.
|
1 | P31695 (/IPI) |
Extracellular matrix structural constituent GO:0005201
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
|
1 | Q9R1B9 (/RCA) |
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
|
1 | O94813 (/IDA) |
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
|
1 | Q90Z44 (/ISA) |
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
|
1 | Q9R1B9 (/ISO) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | O94813 (/IPI) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q90Z44 (/ISA) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q9R1B9 (/ISO) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | O94813 (/IDA) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q90Z44 (/ISA) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q9R1B9 (/ISO) |
Laminin-1 binding GO:0043237
Interacting selectively and non-covalently with laminin-1, a glycoprotein trimer with the subunit composition alpha1, beta1, gamma1.
|
1 | O94813 (/IDA) |
Laminin-1 binding GO:0043237
Interacting selectively and non-covalently with laminin-1, a glycoprotein trimer with the subunit composition alpha1, beta1, gamma1.
|
1 | Q90Z44 (/ISA) |
Laminin-1 binding GO:0043237
Interacting selectively and non-covalently with laminin-1, a glycoprotein trimer with the subunit composition alpha1, beta1, gamma1.
|
1 | Q9R1B9 (/ISO) |
Proteoglycan binding GO:0043394
Interacting selectively and non-covalently with a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
|
1 | O94813 (/IPI) |
Proteoglycan binding GO:0043394
Interacting selectively and non-covalently with a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
|
1 | Q90Z44 (/ISA) |
Proteoglycan binding GO:0043394
Interacting selectively and non-covalently with a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
|
1 | Q9R1B9 (/ISO) |
Heparan sulfate proteoglycan binding GO:0043395
Interacting selectively and non-covalently with a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit.
|
1 | O88279 (/IDA) |
Chemorepellent activity GO:0045499
Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a lower concentration of that signal.
|
1 | Q9R1B9 (/IMP) |
There are 207 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Morphogenesis of a branching structure GO:0001763
The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes.
|
7 | A0A0R4IFT2 (/IMP) A0A2R8RID6 (/IMP) A0A2R8RWP7 (/IMP) A0A2R8RXU4 (/IMP) F1QQE4 (/IMP) P31695 (/IMP) Q9DE36 (/IMP) |
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
7 | A0A0R4IFT2 (/IMP) A0A2R8RID6 (/IMP) A0A2R8RWP7 (/IMP) A0A2R8RXU4 (/IMP) F1QQE4 (/IMP) Q9DE36 (/IMP) Q9R1B9 (/IMP) |
Central nervous system projection neuron axonogenesis GO:0021952
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region.
|
7 | A0A0R4IFT2 (/IGI) A0A2R8Q7E7 (/IGI) A0A2R8RID6 (/IGI) A0A2R8RWP7 (/IGI) A0A2R8RXU4 (/IGI) F1QQE4 (/IGI) Q9DE36 (/IGI) |
Central nervous system projection neuron axonogenesis GO:0021952
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region.
|
7 | A0A0R4IFT2 (/IMP) A0A2R8Q7E7 (/IMP) A0A2R8RID6 (/IMP) A0A2R8RWP7 (/IMP) A0A2R8RXU4 (/IMP) F1QQE4 (/IMP) Q9DE36 (/IMP) |
Negative regulation of axon extension GO:0030517
Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth.
|
7 | A0A0R4IFT2 (/IGI) A0A2R8Q7E7 (/IGI) A0A2R8RID6 (/IGI) A0A2R8RWP7 (/IGI) A0A2R8RXU4 (/IGI) F1QQE4 (/IGI) Q9DE36 (/IGI) |
Negative regulation of axon extension GO:0030517
Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth.
|
7 | A0A0R4IFT2 (/IMP) A0A2R8Q7E7 (/IMP) A0A2R8RID6 (/IMP) A0A2R8RWP7 (/IMP) A0A2R8RXU4 (/IMP) F1QQE4 (/IMP) Q9DE36 (/IMP) |
Endocardial progenitor cell migration to the midline involved in heart field formation GO:0003262
The orderly movement of an endocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into endocardial cells of the heart.
|
6 | A0A0R4IFT2 (/IGI) A0A2R8RID6 (/IGI) A0A2R8RWP7 (/IGI) A0A2R8RXU4 (/IGI) F1QQE4 (/IGI) Q9DE36 (/IGI) |
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
6 | O75093 (/IDA) O75094 (/IDA) O94813 (/IDA) Q80TR4 (/IDA) Q9R1B9 (/IDA) Q9WVB4 (/IDA) |
Axonal defasciculation GO:0007414
Separation of axons away from a bundle of axons known as a fascicle.
|
6 | A0A0R4IFT2 (/IMP) A0A2R8RID6 (/IMP) A0A2R8RWP7 (/IMP) A0A2R8RXU4 (/IMP) F1QQE4 (/IMP) Q9DE36 (/IMP) |
Anterior/posterior axon guidance GO:0033564
The process in which the migration of an axon growth cone is directed to a specific target site along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
|
6 | A0A0R4IFT2 (/IMP) A0A2R8RID6 (/IMP) A0A2R8RWP7 (/IMP) A0A2R8RXU4 (/IMP) F1QQE4 (/IMP) Q9DE36 (/IMP) |
Limb development GO:0060173
The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin.
|
4 | Q90XG2 (/IEP) Q90XG4 (/IEP) Q90Z43 (/IEP) Q90Z44 (/IEP) |
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
3 | Q80TR4 (/ISO) Q9R1B9 (/ISO) Q9WVB4 (/ISO) |
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
3 | B3DJM7 (/NAS) B8A498 (/NAS) Q3S2J2 (/NAS) |
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
3 | O88279 (/IEP) O88280 (/IEP) Q90XG2 (/IEP) |
Cranial nerve morphogenesis GO:0021602
The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.
|
3 | B3DJM7 (/IMP) B8A498 (/IMP) Q3S2J2 (/IMP) |
Positive regulation of axon extension GO:0045773
Any process that activates or increases the frequency, rate or extent of axon extension.
|
3 | B3DJM7 (/IMP) B8A498 (/IMP) Q3S2J2 (/IMP) |
Axon extension involved in axon guidance GO:0048846
The long distance growth of a single cell process, that is involved in the migration of an axon growth cone, where the migration is directed to a specific target site by a combination of attractive and repulsive cues.
|
3 | O75093 (/IDA) O75094 (/IDA) O94813 (/IDA) |
Axon extension involved in axon guidance GO:0048846
The long distance growth of a single cell process, that is involved in the migration of an axon growth cone, where the migration is directed to a specific target site by a combination of attractive and repulsive cues.
|
3 | Q80TR4 (/ISO) Q9R1B9 (/ISO) Q9WVB4 (/ISO) |
Negative chemotaxis GO:0050919
The directed movement of a motile cell or organism towards a lower concentration of a chemical.
|
3 | O75093 (/IDA) O75094 (/IDA) O94813 (/IDA) |
Negative chemotaxis GO:0050919
The directed movement of a motile cell or organism towards a lower concentration of a chemical.
|
3 | O94813 (/IMP) Q80TR4 (/IMP) Q9R1B9 (/IMP) |
Negative chemotaxis GO:0050919
The directed movement of a motile cell or organism towards a lower concentration of a chemical.
|
3 | Q80TR4 (/ISO) Q9R1B9 (/ISO) Q9WVB4 (/ISO) |
Negative regulation of synapse assembly GO:0051964
Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
|
3 | O75093 (/ISS) O88279 (/ISS) Q80TR4 (/ISS) |
Branching involved in blood vessel morphogenesis GO:0001569
The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system.
|
2 | Q99466 (/ISS) Q99466 (/ISS) |
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
|
2 | Q90XG2 (/IEP) Q90XG4 (/IEP) |
Cell fate determination GO:0001709
A process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.
|
2 | Q99466 (/TAS) Q99466 (/TAS) |
Morphogenesis of a branching structure GO:0001763
The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes.
|
2 | Q99466 (/ISS) Q99466 (/ISS) |
Vasculature development GO:0001944
The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.
|
2 | Q99466 (/ISS) Q99466 (/ISS) |
Aortic valve morphogenesis GO:0003180
The process in which the structure of the aortic valve is generated and organized.
|
2 | Q9R1B9 (/IMP) Q9WVB4 (/IMP) |
Aortic valve morphogenesis GO:0003180
The process in which the structure of the aortic valve is generated and organized.
|
2 | O75094 (/ISS) O94813 (/ISS) |
Transcription initiation from RNA polymerase II promoter GO:0006367
Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
|
2 | Q99466 (/TAS) Q99466 (/TAS) |
Positive regulation of transcription of Notch receptor target GO:0007221
The activation of transcription of specific genes as a result of Notch signaling, mediated by the Notch intracellular domain.
|
2 | Q99466 (/TAS) Q99466 (/TAS) |
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
|
2 | Q80TR4 (/IDA) Q9R1B9 (/IDA) |
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
|
2 | Q80TR4 (/IMP) Q9R1B9 (/IMP) |
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
2 | Q90Z43 (/IEP) Q90Z44 (/IEP) |
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
2 | Q80TR4 (/IGI) Q9R1B9 (/IGI) |
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
2 | Q90Z43 (/ISA) Q90Z44 (/ISA) |
Motor neuron axon guidance GO:0008045
The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.
|
2 | Q80TR4 (/ISO) Q9R1B9 (/ISO) |
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
2 | Q9R1B9 (/IGI) Q9WVB4 (/IGI) |
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
2 | Q9R1B9 (/IGI) Q9WVB4 (/IGI) |
Spinal cord development GO:0021510
The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.
|
2 | O88279 (/IEP) O88280 (/IEP) |
Olfactory bulb development GO:0021772
The progression of the olfactory bulb over time from its initial formation until its mature state. The olfactory bulb coordinates neuronal signaling involved in the perception of smell. It receives input from the sensory neurons and outputs to the olfactory cortex.
|
2 | Q80TR4 (/IGI) Q9R1B9 (/IGI) |
Telencephalon cell migration GO:0022029
The orderly movement of a cell from one site to another at least one of which is located in the telencephalon.
|
2 | Q80TR4 (/IGI) Q9R1B9 (/IGI) |
Hemopoiesis GO:0030097
The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
|
2 | Q99466 (/TAS) Q99466 (/TAS) |
Cell differentiation GO:0030154
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
|
2 | Q99466 (/NAS) Q99466 (/NAS) |
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
|
2 | O75094 (/IMP) O94813 (/IMP) |
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
|
2 | Q90Z43 (/ISA) Q90Z44 (/ISA) |
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
|
2 | Q9R1B9 (/ISO) Q9WVB4 (/ISO) |
Mammary gland development GO:0030879
The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages.
|
2 | Q99466 (/IDA) Q99466 (/IDA) |
Retinal ganglion cell axon guidance GO:0031290
The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
|
2 | Q80TR4 (/IGI) Q9R1B9 (/IGI) |
Retinal ganglion cell axon guidance GO:0031290
The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
|
2 | Q80TR4 (/IMP) Q9R1B9 (/IMP) |
Cellular response to hormone stimulus GO:0032870
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
|
2 | O75094 (/IEP) O94813 (/IEP) |
Cellular response to hormone stimulus GO:0032870
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
|
2 | Q90Z43 (/ISA) Q90Z44 (/ISA) |
Dorsal/ventral axon guidance GO:0033563
The process in which the migration of an axon growth cone is directed to a specific target site along the dorsal-ventral body axis in response to a combination of attractive and repulsive cues. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
|
2 | Q80TR4 (/IGI) Q9R1B9 (/IGI) |
MiRNA mediated inhibition of translation GO:0035278
The process in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically mediate repression of translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs
|
2 | Q99466 (/TAS) Q99466 (/TAS) |
Roundabout signaling pathway GO:0035385
A series of molecular signals initiated by the binding of a SLIT protein to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
2 | O75094 (/IMP) O94813 (/IMP) |
Roundabout signaling pathway GO:0035385
A series of molecular signals initiated by the binding of a SLIT protein to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
2 | Q90Z43 (/ISA) Q90Z44 (/ISA) |
Roundabout signaling pathway GO:0035385
A series of molecular signals initiated by the binding of a SLIT protein to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
2 | Q9R1B9 (/ISO) Q9WVB4 (/ISO) |
Negative regulation of cell differentiation GO:0045596
Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation.
|
2 | Q99466 (/NAS) Q99466 (/NAS) |
Negative regulation of endothelial cell differentiation GO:0045602
Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation.
|
2 | Q99466 (/ISS) Q99466 (/ISS) |
Positive regulation of Notch signaling pathway GO:0045747
Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.
|
2 | Q99466 (/TAS) Q99466 (/TAS) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q99466 (/TAS) Q99466 (/TAS) |
Neuron projection morphogenesis GO:0048812
The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
|
2 | Q80TR4 (/IGI) Q9R1B9 (/IGI) |
Inner ear development GO:0048839
The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.
|
2 | Q90Z43 (/IEP) Q90Z44 (/IEP) |
Axon extension involved in axon guidance GO:0048846
The long distance growth of a single cell process, that is involved in the migration of an axon growth cone, where the migration is directed to a specific target site by a combination of attractive and repulsive cues.
|
2 | Q90Z43 (/ISA) Q90Z44 (/ISA) |
Negative chemotaxis GO:0050919
The directed movement of a motile cell or organism towards a lower concentration of a chemical.
|
2 | Q90Z43 (/ISA) Q90Z44 (/ISA) |
Response to cortisol GO:0051414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.
|
2 | O75094 (/IEP) O94813 (/IEP) |
Response to cortisol GO:0051414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.
|
2 | Q90Z43 (/ISA) Q90Z44 (/ISA) |
Ventricular septum morphogenesis GO:0060412
The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.
|
2 | Q9R1B9 (/IMP) Q9WVB4 (/IMP) |
Ventricular septum morphogenesis GO:0060412
The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.
|
2 | O75094 (/ISS) O94813 (/ISS) |
Apoptotic process involved in luteolysis GO:0061364
The apoptotic process that contributes to luteolysis.
|
2 | O75094 (/IEP) O94813 (/IEP) |
Apoptotic process involved in luteolysis GO:0061364
The apoptotic process that contributes to luteolysis.
|
2 | Q90Z43 (/ISA) Q90Z44 (/ISA) |
Negative regulation of chemokine-mediated signaling pathway GO:0070100
Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor.
|
2 | O75094 (/IMP) O94813 (/IMP) |
Negative regulation of chemokine-mediated signaling pathway GO:0070100
Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor.
|
2 | Q90Z43 (/ISA) Q90Z44 (/ISA) |
Negative regulation of chemokine-mediated signaling pathway GO:0070100
Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor.
|
2 | Q9R1B9 (/ISO) Q9WVB4 (/ISO) |
Ossification GO:0001503
The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
|
1 | Q90XG4 (/IEP) |
Branching involved in blood vessel morphogenesis GO:0001569
The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system.
|
1 | P31695 (/IMP) |
Metanephros development GO:0001656
The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.
|
1 | Q9R1B9 (/IMP) |
Ureteric bud development GO:0001657
The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure.
|
1 | O94813 (/IMP) |
Ureteric bud development GO:0001657
The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure.
|
1 | Q90Z44 (/ISA) |
Ureteric bud development GO:0001657
The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure.
|
1 | Q9R1B9 (/ISO) |
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
|
1 | Q9R1B9 (/IMP) |
Endothelial cell morphogenesis GO:0001886
The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell.
|
1 | Q6MG89 (/IDA) |
Endothelial cell morphogenesis GO:0001886
The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell.
|
1 | P31695 (/ISO) |
Negative regulation of protein phosphorylation GO:0001933
Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.
|
1 | O94813 (/IDA) |
Negative regulation of protein phosphorylation GO:0001933
Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.
|
1 | Q90Z44 (/ISA) |
Negative regulation of protein phosphorylation GO:0001933
Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.
|
1 | Q9R1B9 (/ISO) |
Vasculature development GO:0001944
The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.
|
1 | P31695 (/IMP) |
Cell migration involved in sprouting angiogenesis GO:0002042
The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels involved in sprouting angiogenesis.
|
1 | O94813 (/IMP) |
Cell migration involved in sprouting angiogenesis GO:0002042
The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels involved in sprouting angiogenesis.
|
1 | Q90Z44 (/ISA) |
Cell migration involved in sprouting angiogenesis GO:0002042
The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels involved in sprouting angiogenesis.
|
1 | Q9R1B9 (/ISO) |
Negative regulation of leukocyte chemotaxis GO:0002689
Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis.
|
1 | O94813 (/IDA) |
Negative regulation of leukocyte chemotaxis GO:0002689
Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis.
|
1 | Q90Z44 (/ISA) |
Negative regulation of leukocyte chemotaxis GO:0002689
Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis.
|
1 | Q9R1B9 (/ISO) |
Atrioventricular valve morphogenesis GO:0003181
The process in which the structure of the atrioventricular valve is generated and organized.
|
1 | Q9WVB4 (/IMP) |
Atrioventricular valve morphogenesis GO:0003181
The process in which the structure of the atrioventricular valve is generated and organized.
|
1 | O75094 (/ISS) |
Pulmonary valve morphogenesis GO:0003184
The process in which the structure of the pulmonary valve is generated and organized.
|
1 | Q9R1B9 (/IMP) |
Pulmonary valve morphogenesis GO:0003184
The process in which the structure of the pulmonary valve is generated and organized.
|
1 | O94813 (/ISS) |
Nuclear migration GO:0007097
The directed movement of the nucleus to a specific location within a cell.
|
1 | Q80TR4 (/IDA) |
Notch signaling pathway GO:0007219
A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | P31695 (/TAS) |
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
1 | O94813 (/TAS) |
Motor neuron axon guidance GO:0008045
The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.
|
1 | O94813 (/IDA) |
Motor neuron axon guidance GO:0008045
The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.
|
1 | O75093 (/IMP) |
Motor neuron axon guidance GO:0008045
The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.
|
1 | Q90Z44 (/ISA) |
Regulation of Notch signaling pathway GO:0008593
Any process that modulates the frequency, rate or extent of the Notch signaling pathway.
|
1 | P31695 (/IGI) |
Animal organ morphogenesis GO:0009887
Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
|
1 | Q9WVB4 (/IGI) |
Animal organ morphogenesis GO:0009887
Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
|
1 | Q9WVB4 (/IMP) |
Negative regulation of lamellipodium assembly GO:0010593
Any process that decreases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
|
1 | O94813 (/IDA) |
Negative regulation of lamellipodium assembly GO:0010593
Any process that decreases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
|
1 | Q90Z44 (/ISA) |
Negative regulation of lamellipodium assembly GO:0010593
Any process that decreases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
|
1 | Q9R1B9 (/ISO) |
Negative regulation of endothelial cell migration GO:0010596
Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
|
1 | O94813 (/IDA) |
Negative regulation of endothelial cell migration GO:0010596
Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
|
1 | Q90Z44 (/ISA) |
Negative regulation of endothelial cell migration GO:0010596
Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
|
1 | Q9R1B9 (/ISO) |
Negative regulation of smooth muscle cell migration GO:0014912
Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration.
|
1 | O94813 (/IDA) |
Negative regulation of smooth muscle cell migration GO:0014912
Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration.
|
1 | Q90Z44 (/ISA) |
Negative regulation of smooth muscle cell migration GO:0014912
Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration.
|
1 | Q9R1B9 (/ISO) |
Chemorepulsion involved in postnatal olfactory bulb interneuron migration GO:0021836
The creation and reception of signals that repel olfactory bulb interneurons from the subventricular zone as a component process in tangential migration.
|
1 | O94813 (/IDA) |
Chemorepulsion involved in postnatal olfactory bulb interneuron migration GO:0021836
The creation and reception of signals that repel olfactory bulb interneurons from the subventricular zone as a component process in tangential migration.
|
1 | Q90Z44 (/ISA) |
Chemorepulsion involved in postnatal olfactory bulb interneuron migration GO:0021836
The creation and reception of signals that repel olfactory bulb interneurons from the subventricular zone as a component process in tangential migration.
|
1 | Q9R1B9 (/ISO) |
Neural tube development GO:0021915
The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium.
|
1 | Q90XG2 (/IEP) |
Corticospinal neuron axon guidance through spinal cord GO:0021972
The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after decussation through the spinal cord in response to a combination of attractive and repulsive cues.
|
1 | O94813 (/IMP) |
Corticospinal neuron axon guidance through spinal cord GO:0021972
The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after decussation through the spinal cord in response to a combination of attractive and repulsive cues.
|
1 | Q90Z44 (/ISA) |
Corticospinal neuron axon guidance through spinal cord GO:0021972
The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after decussation through the spinal cord in response to a combination of attractive and repulsive cues.
|
1 | Q9R1B9 (/ISO) |
Tangential migration from the subventricular zone to the olfactory bulb GO:0022028
The migration of cells in the telencephalon from the subventricular zone to the olfactory bulb in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration.
|
1 | Q80TR4 (/IMP) |
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
|
1 | O94813 (/IDA) |
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
|
1 | O94813 (/IMP) |
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
|
1 | Q90Z44 (/ISA) |
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
|
1 | Q9R1B9 (/ISO) |
Negative regulation of axon extension GO:0030517
Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth.
|
1 | Q9R1B9 (/IDA) |
Negative regulation of actin filament polymerization GO:0030837
Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization.
|
1 | O94813 (/IDA) |
Negative regulation of actin filament polymerization GO:0030837
Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization.
|
1 | Q90Z44 (/ISA) |
Negative regulation of actin filament polymerization GO:0030837
Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization.
|
1 | Q9R1B9 (/ISO) |
Mammary gland development GO:0030879
The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages.
|
1 | P31695 (/ISO) |
Retinal ganglion cell axon guidance GO:0031290
The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
|
1 | O94813 (/IDA) |
Retinal ganglion cell axon guidance GO:0031290
The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
|
1 | Q90Z44 (/ISA) |
Retinal ganglion cell axon guidance GO:0031290
The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
|
1 | Q9R1B9 (/ISO) |
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
|
1 | P31695 (/IDA) |
Dorsal/ventral axon guidance GO:0033563
The process in which the migration of an axon growth cone is directed to a specific target site along the dorsal-ventral body axis in response to a combination of attractive and repulsive cues. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
|
1 | Q9R1B9 (/IMP) |
Negative regulation of GTPase activity GO:0034260
Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.
|
1 | Q90Z44 (/ISA) |
Roundabout signaling pathway GO:0035385
A series of molecular signals initiated by the binding of a SLIT protein to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | O94813 (/IC) |
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
|
1 | Q6MG89 (/IEP) |
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
1 | O94813 (/IMP) |
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
1 | Q90Z44 (/ISA) |
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
1 | Q9R1B9 (/ISO) |
Negative regulation of catalytic activity GO:0043086
Any process that stops or reduces the activity of an enzyme.
|
1 | Q90Z44 (/ISA) |
Negative regulation of vascular permeability GO:0043116
Any process that reduces the extent to which blood vessels can be pervaded by fluid.
|
1 | O94813 (/IDA) |
Negative regulation of vascular permeability GO:0043116
Any process that reduces the extent to which blood vessels can be pervaded by fluid.
|
1 | Q90Z44 (/ISA) |
Negative regulation of vascular permeability GO:0043116
Any process that reduces the extent to which blood vessels can be pervaded by fluid.
|
1 | Q9R1B9 (/ISO) |
Endothelial cell differentiation GO:0045446
The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.
|
1 | Q6MG89 (/IDA) |
Endothelial cell differentiation GO:0045446
The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.
|
1 | P31695 (/ISO) |
Negative regulation of endothelial cell differentiation GO:0045602
Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation.
|
1 | P31695 (/IMP) |
Regulation of myoblast differentiation GO:0045661
Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
|
1 | D2XV92 (/IMP) |
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
|
1 | P31695 (/IDA) |
Positive regulation of angiogenesis GO:0045766
Any process that activates or increases angiogenesis.
|
1 | P31695 (/IMP) |
Branching morphogenesis of an epithelial tube GO:0048754
The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder.
|
1 | O94813 (/IDA) |
Branching morphogenesis of an epithelial tube GO:0048754
The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder.
|
1 | O94813 (/IMP) |
Branching morphogenesis of an epithelial tube GO:0048754
The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder.
|
1 | Q90Z44 (/ISA) |
Branching morphogenesis of an epithelial tube GO:0048754
The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder.
|
1 | Q9R1B9 (/ISO) |
Neuron projection morphogenesis GO:0048812
The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
|
1 | Q9R1B9 (/IMP) |
Negative regulation of axon extension involved in axon guidance GO:0048843
Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in axon guidance.
|
1 | O88279 (/IDA) |
Negative regulation of axon extension involved in axon guidance GO:0048843
Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in axon guidance.
|
1 | Q80TR4 (/ISO) |
Venous blood vessel morphogenesis GO:0048845
The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart.
|
1 | P31695 (/IMP) |
Forebrain morphogenesis GO:0048853
The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).
|
1 | O75093 (/NAS) |
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
|
1 | Q9R1B9 (/ISO) |
Positive regulation of axonogenesis GO:0050772
Any process that activates or increases the frequency, rate or extent of axonogenesis.
|
1 | O94813 (/TAS) |
Induction of negative chemotaxis GO:0050929
Any process that initiates the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.
|
1 | O94813 (/IDA) |
Induction of negative chemotaxis GO:0050929
Any process that initiates the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.
|
1 | Q90Z44 (/ISA) |
Induction of negative chemotaxis GO:0050929
Any process that initiates the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.
|
1 | Q9R1B9 (/ISO) |
Negative regulation of small GTPase mediated signal transduction GO:0051058
Any process that stops, prevents, or reduces the frequency, rate or extent of small GTPase mediated signal transduction.
|
1 | O94813 (/IDA) |
Negative regulation of small GTPase mediated signal transduction GO:0051058
Any process that stops, prevents, or reduces the frequency, rate or extent of small GTPase mediated signal transduction.
|
1 | Q90Z44 (/ISA) |
Negative regulation of small GTPase mediated signal transduction GO:0051058
Any process that stops, prevents, or reduces the frequency, rate or extent of small GTPase mediated signal transduction.
|
1 | Q9R1B9 (/ISO) |
Cartilage development GO:0051216
The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
|
1 | Q90XG4 (/IEP) |
Myoblast migration GO:0051451
The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
|
1 | Q90Z44 (/IEP) |
Regulation of cytoskeleton organization GO:0051493
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
|
1 | D2XV92 (/IMP) |
Negative regulation of synapse assembly GO:0051964
Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
|
1 | Q3S2J2 (/IMP) |
Mammary gland duct morphogenesis GO:0060603
The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk.
|
1 | Q9R1B9 (/IGI) |
Mammary gland duct morphogenesis GO:0060603
The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk.
|
1 | Q9R1B9 (/IMP) |
Mammary duct terminal end bud growth GO:0060763
The morphogenetic growth of the large, club-shaped terminal end of a mammary gland duct during prepubertal growth and during puberty.
|
1 | Q9R1B9 (/IMP) |
Trigeminal ganglion formation GO:0061561
The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts.
|
1 | D2XV92 (/IMP) |
Trigeminal ganglion structural organization GO:0061563
The process that contributes to creating the structural organization of the trigeminal ganglion This process pertains to the physical shaping of a rudimentary structure.
|
1 | D2XV92 (/IMP) |
Regulation of protein processing GO:0070613
Any process that modulates the frequency, rate or extent of protein processing, any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein.
|
1 | P31695 (/IDA) |
Cellular response to heparin GO:0071504
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.
|
1 | O94813 (/IDA) |
Cellular response to heparin GO:0071504
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.
|
1 | Q90Z44 (/ISA) |
Cellular response to heparin GO:0071504
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.
|
1 | Q9R1B9 (/ISO) |
Negative regulation of smooth muscle cell chemotaxis GO:0071672
Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis.
|
1 | O94813 (/IDA) |
Negative regulation of smooth muscle cell chemotaxis GO:0071672
Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis.
|
1 | Q90Z44 (/ISA) |
Negative regulation of smooth muscle cell chemotaxis GO:0071672
Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis.
|
1 | Q9R1B9 (/ISO) |
Negative regulation of mononuclear cell migration GO:0071676
Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.
|
1 | O94813 (/IDA) |
Negative regulation of mononuclear cell migration GO:0071676
Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.
|
1 | Q90Z44 (/ISA) |
Negative regulation of mononuclear cell migration GO:0071676
Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.
|
1 | Q9R1B9 (/ISO) |
Protein localization to adherens junction GO:0071896
Any process in which a protein is transported to, and/or maintained at the adherens junction.
|
1 | D2XV92 (/IMP) |
Negative regulation of neutrophil chemotaxis GO:0090024
Any process that decreases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
|
1 | O94813 (/IDA) |
Negative regulation of neutrophil chemotaxis GO:0090024
Any process that decreases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
|
1 | Q90Z44 (/ISA) |
Negative regulation of neutrophil chemotaxis GO:0090024
Any process that decreases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
|
1 | Q9R1B9 (/ISO) |
Negative regulation of monocyte chemotaxis GO:0090027
Any process that decreases the frequency, rate, or extent of monocyte chemotaxis.
|
1 | Q9R1B9 (/ISO) |
Negative regulation of monocyte chemotaxis GO:0090027
Any process that decreases the frequency, rate, or extent of monocyte chemotaxis.
|
1 | O94813 (/ISS) |
Negative regulation of retinal ganglion cell axon guidance GO:0090260
Any process that decreases the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
|
1 | O94813 (/IDA) |
Negative regulation of retinal ganglion cell axon guidance GO:0090260
Any process that decreases the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
|
1 | Q90Z44 (/ISA) |
Negative regulation of retinal ganglion cell axon guidance GO:0090260
Any process that decreases the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
|
1 | Q9R1B9 (/ISO) |
Negative regulation of cellular response to growth factor stimulus GO:0090288
Any process that decreases the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
|
1 | O94813 (/IDA) |
Negative regulation of cellular response to growth factor stimulus GO:0090288
Any process that decreases the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
|
1 | Q90Z44 (/ISA) |
Negative regulation of cellular response to growth factor stimulus GO:0090288
Any process that decreases the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
|
1 | Q9R1B9 (/ISO) |
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
|
1 | Q9R1B9 (/IGI) |
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
|
1 | Q9R1B9 (/IMP) |
Cell aggregation GO:0098743
The clustering together and adhesion of initially separate cells to form an aggregate. Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation.
|
1 | D2XV92 (/IMP) |
Positive regulation of aorta morphogenesis GO:1903849
Any process that activates or increases the frequency, rate or extent of aorta morphogenesis.
|
1 | P31695 (/IMP) |
Regulation of myotome development GO:2000290
Any process that modulates the frequency, rate or extent of myotome development.
|
1 | D2XV92 (/IMP) |
Roundabout signaling pathway involved in axon guidance GO:2001266
Any Roundabout signaling pathway that is involved in axon guidance.
|
1 | D2XV92 (/IMP) |
There are 30 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
8 | O94813 (/TAS) P31695 (/TAS) Q3S2J2 (/TAS) Q80TR4 (/TAS) Q99466 (/TAS) Q99466 (/TAS) Q9R1B9 (/TAS) Q9WVB4 (/TAS) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
6 | O75094 (/IDA) O88279 (/IDA) O94813 (/IDA) Q80TR4 (/IDA) Q9R1B9 (/IDA) Q9WVB4 (/IDA) |
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
|
5 | D2XV92 (/IDA) F1NF14 (/IDA) Q90XG4 (/IDA) Q90Z43 (/IDA) Q90Z44 (/IDA) |
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
3 | O94813 (/TAS) Q99466 (/TAS) Q99466 (/TAS) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
3 | Q80TR4 (/ISO) Q9R1B9 (/ISO) Q9WVB4 (/ISO) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
3 | P31695 (/TAS) Q99466 (/TAS) Q99466 (/TAS) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | P31695 (/TAS) Q99466 (/TAS) Q99466 (/TAS) |
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
|
2 | Q99466 (/TAS) Q99466 (/TAS) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | Q9R1B9 (/HDA) Q9WVB4 (/HDA) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | Q90Z43 (/ISA) Q90Z44 (/ISA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q99466 (/TAS) Q99466 (/TAS) |
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
2 | Q99466 (/TAS) Q99466 (/TAS) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q99466 (/TAS) Q99466 (/TAS) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | Q99466 (/IDA) Q99466 (/IDA) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | O75093 (/NAS) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | O94813 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q90Z44 (/ISA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9R1B9 (/ISO) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | O75094 (/NAS) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | P31695 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9R1B9 (/ISO) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | P31695 (/ISO) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | P31695 (/ISS) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | O88280 (/IDA) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q9WVB4 (/ISO) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | O94813 (/NAS) |
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
|
1 | P31695 (/IDA) |
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
|
1 | Q9R1B9 (/HDA) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | O94813 (/HDA) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q90Z44 (/ISA) |