CATH Superfamily 2.10.110.10

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
1	Cysteine and glycine-rich protein 1	1316	3D	2o13A00	-	90.9
2	LIM domain and actin-binding 1	1304	3D	2d8yA01	-	95.7
3	actin-binding LIM protein 1 isoform X1	1226	3D	1v6gA00	-	82.2
4	actin-binding LIM protein 1 isoform X1	1121	3D	1wigA00	-	83.5
5	Testin isoform 1	1078	3D	2xqnT01	-	98.0
6	LIM homeobox transcription factor 1-beta	1072		-	-	94.2
7	actin-binding LIM protein 1 isoform X1	989	3D	2dj7A00	-	75.9
8	Paxillin isoform 1	907		-	-	98.3
9	Paxillin isoform 1	880		-	-	91.2
10	PDZ and LIM domain protein 5	861		-	-	90.8
11	Lim and senescent cell antigen-like-containing	857		-	-	80.7
13	Four and a half LIM domains 1	833	3D	2d8zA00	-	87.6
12	Paxillin isoform 1	831	3D	1x3hA00	-	87.8
14	PDZ and LIM domain protein 5	795	3D	2darA01	-	88.0
16	LIM domain only 3	793	3D	2lxdA00	-	64.6
15	LIM domain only 3	788	3D	2dfyX01	-	61.1
17	Lim and senescent cell antigen-like-containing	759	3D	2d8xA00	-	78.9
18	Paxillin isoform 1	752		-	-	94.5
19	Lim and senescent cell antigen-like-containing	719	3D	2corA00	-	87.8
20	PDZ and LIM domain protein 5	715		-	-	89.7
21	Lim and senescent cell antigen-like-containing	693	3D	4hi9B00	-	81.0
22	prickle-like protein 2 isoform X1	647		-	-	72.9
23	LIM homeobox 6	565		-	-	81.0
24	actin-binding LIM protein 1 isoform X1	541		-	-	81.2
25	Cysteine-rich protein 2	536	3D	2cu8A00	-	80.5
26	PDZ and LIM domain protein 3	517	3D	1x64A01	-	89.3
27	lipoma-preferred partner isoform X1	514	3D	2dloA00	-	83.7
28	LIM domain-containing protein 1	497		-	-	77.6
29	LIM and senescent cell antigen-like-containing domain protein	483		-	-	78.2
30	Four and a half LIM domains protein 2	479	3D	1wyhA00	-	91.8
31	LIM homeobox 6, isoform CRA_b	474		-	-	89.5
32	LIM/homeobox protein Lhx3	456	3D	6cmeB02	-	81.0
33	LIM/homeobox protein Lhx9 isoform X2	449		-	-	90.6
34	Insulin gene enhancer protein ISL	445	3D	4jcjC01	-	90.1
35	prickle-like protein 2 isoform X1	426		-	-	91.8
36	LIM domain-containing protein 1	425		-	-	75.6
37	LIM domain-containing protein 1	416		-	-	87.5
38	LIM domain kinase 2	414	3D	1x6aA01	-	83.5
39	LIM/homeobox protein Lhx9 isoform 2	353		-	-	77.4
41	LIM and calponin homology domains 1	350		-	-	77.4
40	LIM homeobox transcription factor 1 beta	350		-	-	77.8
42	lipoma-preferred partner isoform X1	332		-	-	71.4
43	protein-methionine sulfoxide oxidase MICAL3 isoform X2	327		-	-	79.4
44	Rho GTPase activator Rga	319		-	-	61.4
45	LIM domain-binding protein 1 isoform X1	317		-	-	72.3
46	LIM/homeobox protein Lhx1	316		-	-	74.3
47	lipoma-preferred partner isoform X1	308	3D	1x61A00	-	84.3
48	Four and a half LIM domains protein 2	304	3D	1x4lA00	-	75.5
50	Four and a half LIM domains protein 1	276	3D	1x63A00	-	84.6
49	Four and a half LIM domains protein 2	275		-	-	79.4
51	LIM domain transcription factor LMO4	254	3D	2mbvA00	-	69.3
52	Four and a half LIM domains 1	248	3D	2cupA01	-	89.1
53	Actin-binding LIM protein family, member 2	226		-	-	71.1
54	Cysteine-rich protein 1	215		-	-	96.1
56	insulin gene enhancer protein ISL-1	203	3D	4jcjC02	-	84.1
55	Actin binding LIM protein 1	200		-	-	90.8
57	Zyxin	194		-	-	82.5
58	Rho GTPase activator Lrg11	189		-	-	73.4
59	LIM domain only 2	186	3D	4kfzB01	-	31.5
60	Uncharacterized protein, isoform Z	182		-	-	90.8
61	Testin	177	3D	2xqnT02	-	73.9
62	LIM domain-containing protein	162		-	-	59.0
63	LIM domain-binding protein 2 isoform X2	161		-	-	66.4
64	Four and a half LIM domains protein 3	156	3D	2eheA00	-	59.4
65	Testin	154		-	-	58.6
66	Four and a half LIM domains protein	149		-	-	92.3
67	Uncharacterized protein, isoform Z	147		-	-	56.5
68	Insulin gene enhancer protein ISL-2	145		-	-	81.3
69	Uncharacterized protein, isoform Z	143		-	-	91.4
70	Four and a half LIM domains 3	141		-	-	90.9
71	nebulin-related-anchoring protein isoform X1	140		-	-	62.9
72	Four and a half LIM domains protein 1	139	3D	2egqA00	-	85.7
73	Uncharacterized protein, isoform Z	138		-	-	82.3
74	Rho-type GTPase-activating protein 1	133		-	-	39.6
75	Actin-binding lim protein 1	131		-	-	62.4
76	Zyxin	130		-	-	76.8
77	LIM domain protein	119		-	-	86.6
78	Protein DA1-related 1	114		-	-	80.9
79	LIM and cysteine-rich domains protein 1	110		-	-	71.4
80	actin-binding LIM protein 1 isoform X6	108		-	-	69.8
81	Uncharacterized protein, isoform A	107		-	-	83.2
82	LIM domain kinase 1	104		-	-	95.1
83	LIM domain kinase 1	96		-	-	67.8
84	transforming growth factor beta-1-induced transcript 1 protein	94		-	-	37.9
85	PDZ and LIM domain 2 mystique	93		-	-	63.6
86	Filamin binding LIM protein 1	91		-	-	89.1
88	Filamin binding LIM protein 1	91		-	-	81.7
87	LIM zinc-binding domain-containing Nebulette	91		-	-	87.4
89	LIM and SH3 domain protein 1	84		-	-	52.6
90	LIM domain kinase 2	81		-	-	70.1
92	LIM domain-containing protein	77		-	-	70.3
91	Sciellin	77		-	-	21.1
93	prickle-like protein 4 isoform X3	75		-	-	80.2
94	LIM domain-containing protein	71		-	-	82.6
95	four and a half LIM domains protein 3	66		-	-	72.0
96	LIM domain kinase 2 isoform X2	66		-	-	30.2
97	Filamin-binding LIM protein 1	65		-	-	86.4
98	Uncoordinated 115a, isoform B	63		-	-	60.1
99	Uncoordinated 115a, isoform B	57		-	-	61.1
101	Zinc finger protein 185 with LIM domain	56		-	-	25.3
100	MICAL-like protein 1	56		-	-	80.9
102	LIM and SH3 domain protein Lasp	54		-	-	74.8
103	LIM homeobox transcription factor 1-beta	54		-	-	86.8
104	Ras association domain-containing protein 2	51		-	-	77.4
105	Similar to LIM domain-containing protein	47		-	-	78.4
106	F-actin-monooxygenase MICAL1 isoform 1	46	3D	2co8A00	-	75.8
107	Protein DA1-related 2	43		-	-	81.8
108	LIM domain containing protein	39		-	-	88.3
109	Lipoma preferred partner	37		-	-	81.9
111	Four and a half LIM domains protein 3	36		-	-	31.7
110	Nebulin related anchoring protein	36		-	-	86.2
112	Rho GTPase activator Lrg11	31		-	-	77.9
114	Apterous, isoform B	29		-	-	81.1
113	LIM domain-containing protein	29		-	-	91.3
120	Insulin gene enhancer protein ISL-2	25	3D	6cmeB01	-	79.3
116	Ap, isoform A	24		-	-	48.0
115	Rho GTPase-activating protein	24		-	-	65.3
117	CBN-TAG-273 protein	22		-	-	15.4
118	protein-methionine sulfoxide oxidase Mical isoform X4	21		-	-	37.6
119	LIM domain protein	20		-	-	76.5
121	Rho GTPase activator Rga	19		-	-	56.6
122	LIM domain and actin-binding protein	18		-	-	82.4
124	Cysteine and glycine-rich protein 1a	17		-	-	65.6
123	Rho GTPase-activating protein	17		-	-	58.3
125	Four and a half LIM domains 2	17		-	-	23.9
126	Chromosome 23, whole genome shotgun sequence	16		-	-	70.4
129	LIM domain-containing protein	15		-	-	38.4
128	Pxl1p	15		-	-	72.9
127	LIM domain protein	15		-	-	52.3
130	Protein CBG03641	14		-	-	62.2
134	Lrg1p	13		-	-	42.6
131	LIM domain-containing protein	13		-	-	47.8
132	Pxl1p	13		-	-	43.0
136	LIM domain family	13		-	-	95.0
135	LIM domain-containing protein, putative	13		-	-	91.8
133	Uncharacterized protein	13		-	-	25.7
137	Mechanosensory protein 3	12		-	-	79.1
138	Signal transducer	11		-	-	36.7
142	Lrg1p	11		-	-	47.3
139	Protein CBR-ZYX-1	11		-	-	62.3
141	LIM domain-containing protein	11		-	-	76.1
143	Protein CBG21573	11		-	-	5.0
140	Cysteine and glycine-rich protein 1	11		-	-	32.6
146	ALP/Enigma encoding	10		-	-	81.5
144	Protein CBR-ZYX-1	10		-	-	17.5
145	Cysteine and glycine-rich protein	10		-	-	85.4
147	LIM/homeobox protein Awh-like protein	10		-	-	74.0
149	FHL1 isoform 27	9		-	-	20.2
150	Actin binding LIM protein family member 3	9		-	-	4.7
153	Rho GTPase activator Lrg11	9		-	-	42.3
148	Protein CBR-ZYX-1	9		-	-	15.6
152	Four and a half LIM domains protein 2	9		-	-	13.3
151	Uncharacterized protein, isoform G	9		-	-	3.3
154	LIM and senescent cell antigen-like-containing domain protein 1	9		-	-	78.8
155	Protein CBG12788	8		-	-	25.1
157	LIM/homeobox protein Lhx2	8		-	-	31.3
159	Lrg1p	8		-	-	9.1
156	LIM Zinc finger domain containing protein	8		-	-	13.4
158	LIM/homeobox protein ttx-3	8		-	-	68.5
167	Predicted protein	7		-	-	61.4
172	Protein CBG11874	7		-	-	79.5
163	LIM domain-containing protein ajuba isoform 2	7		-	-	30.4
160	Signal transducer, putative	7		-	-	77.8
171	Actin-binding LIM protein family member 2	7		-	-	20.2
165	Protein CBG12788	7		-	-	22.0
170	LIM domain-containing protein B	7		-	-	85.2
168	LIM Zinc finger domain containing protein	7		-	-	5.4
164	Prickle planar cell polarity protein 4	7		-	-	47.3
161	MIT domain containing protein	7		-	-	13.1
162	LD14485p	7		-	-	8.4
166	LIM domain containing protein, expressed	7		-	-	3.9
169	ISL LIM homeobox 2	7		-	-	83.6
179	Calponin homology and LIM domain-containing protein	6		-	-	52.7
176	LIM domain-containing protein pin-2	6		-	-	26.7
180	GM16078	6		-	-	85.6
174	Calpain family cysteine protease	6		-	-	7.1
178	LIM domain family	6		-	-	75.1
175	GD25476	6		-	-	14.4
173	XLIM-Kinases2	6		-	-	80.4
177	LIM homeobox 9	6		-	-	84.2
185	Homeobox protein ceh-14	5		-	-	22.0
190	LIM domain protein	5		-	-	90.2
183	Chromosome 10, whole genome shotgun sequence	5		-	-	17.6
187	LIM and Rho-GAP domain-containing protein	5		-	-	3.0
189	Uncharacterized protein	5		-	-	85.9
186	Actin binding LIM protein family member 2	5		-	-	31.7
182	Putative actin-binding protein UNC-115	5		-	-	28.1
181	Rho-type GTPase-activating protein 1	5		-	-	11.9
184	DA1-related protein 7	5		-	-	39.3
191	LIM domain kinase 2	5		-	-	34.9
188	PDZ and LIM domain protein Zasp-like Protein	5		-	-	80.8
195	Paxillin homolog 1	4		-	-	15.8
193	LIM homeobox 4	4		-	-	43.9
202	LIM-domain protein	4		-	-	61.7
201	Transforming growth factor beta 1-induced transcript 1	4		-	-	44.0
197	Transforming growth factor beta 1-induced transcript 1	4		-	-	7.9
204	LIM homeobox transcription factor 1, alpha	4		-	-	80.1
199	Uncharacterized protein	4		-	-	0.0
203	LIM domain-containing protein	4		-	-	55.8
200	Uncharacterized protein	4		-	-	1.7
196	Paxillin	4		-	-	16.4
192	Wilms tumor protein 1-interacting protein-like protein	4		-	-	27.7
194	LIM domain-containing protein PLIM2c	4		-	-	9.0
198	Uncharacterized protein	4		-	-	0.0
221	Rho-GTPase-activating protein, putative	3		-	-	1.6
216	Four and a half LIM domains 5	3		-	-	2.0
209	LIM homeobox 2b	3		-	-	52.3
212	Protein CBR-LIM-9	3		-	-	48.8
224	transcription factor protein	3		-	-	84.2
219	Uncharacterized protein	3		-	-	20.0
206	Thyroid hormone receptor interactor 6	3		-	-	34.9
208	Protein CBG11874	3		-	-	34.2
214	FHL1 isoform 15	3		-	-	0.0
218	Four and a half LIM domains protein 5	3		-	-	0.0
222	LIM and senescent cell antigen-like-containing domain protein 2 isoform X4	3		-	-	38.3
211	Uncharacterized protein	3		-	-	3.7
210	Actin-binding LIM protein family, member 3	3		-	-	73.1
213	Four and a half LIM domains protein 2	3		-	-	10.5
205	Uncharacterized protein	3		-	-	75.3
215	LIM domain-containing protein pin-2	3		-	-	18.5
207	GM16078	3		-	-	14.2
225	LIM domain-containing protein F	3		-	-	82.2
220	Rho-GTPase-activating protein, putative	3		-	-	14.0
223	PDZ and LIM domain 5	3		-	-	42.6
217	LIM domain family	3		-	-	3.3
248	Uncharacterized protein	2		-	-	1.8
265	transcription factor protein	2		-	-	2.1
244	Uncharacterized protein, isoform C	2		-	-	53.8
241	YALI0A18381p	2		-	-	0.0
232	LIM and PET domains protein	2		-	-	2.1
228	LIM homeobox 8	2		-	-	43.1
236	Lim homeobox protein, putative	2		-	-	0.0
239	Uncharacterized protein	2		-	-	8.9
274	LIM domain-containing protein B	2		-	-	6.5
263	Protein CBR-LIM-7	2		-	-	17.8
260	Uncharacterized protein	2		-	-	1.2
257	Transcription factor Lmx1b	2		-	-	25.2
278	Chromosome 19, whole genome shotgun sequence	2		-	-	14.2
271	Four and a half LIM domains protein 2	2		-	-	5.0
249	LIM domain transcription factor LMO4-like Protein	2		-	-	8.1
250	Uncharacterized protein	2		-	-	48.5
276	ABL207Wp	2		-	-	0.0
267	LIM homeobox 2a	2		-	-	1.8
272	LIM and senescent cell antigen-like-containing domain protein	2		-	-	11.3
229	LIM-domain containing phosphatase	2		-	-	52.4
253	Ci-Fhl1/2/3 protein	2		-	-	10.2
280	YALI0F13211p	2		-	-	0.0
283	Predicted protein	2		-	-	43.8
238	Predicted protein	2		-	-	0.0
226	Uncharacterized protein	2		-	-	0.0
279	YALI0F13211p	2		-	-	0.0
234	Uncharacterized protein	2		-	-	9.1
285	LIM-domain containing phosphatase	2		-	-	43.9
231	LIM and PET domains protein	2		-	-	2.0
255	Paxillin	2		-	-	6.1
242	YALI0A18381p	2		-	-	0.0
246	LIM domain-containing protein WLIM2a	2		-	-	0.0
269	LIM and senescent cell antigen-like-containing domain protein 1	2		-	-	0.0
233	LIM and PET domains protein	2		-	-	0.0
230	Uncharacterized protein	2		-	-	20.9
227	Protein DA1-related 5	2		-	-	40.3
247	YALI0D18898p	2		-	-	0.0
251	Uncharacterized protein	2		-	-	52.7
235	Uncharacterized protein	2		-	-	0.0
281	Filamin binding LIM protein 1	2		-	-	42.6
284	Uncharacterized protein	2		-	-	44.3
254	Uncharacterized protein	2		-	-	0.0
262	Protein CBR-LIM-7	2		-	-	17.6
258	Uncharacterized protein	2		-	-	18.7
277	Uncharacterized protein	2		-	-	0.0
266	Insulin gene enhancer protein ISL-1	2		-	-	6.7
282	Uncharacterized protein	2		-	-	47.6
268	Ttx-3	2		-	-	0.0
270	LIM domain-containing protein	2		-	-	0.0
256	Uncharacterized protein	2		-	-	42.3
245	Chromosome 21, whole genome shotgun sequence	2		-	-	48.5
273	Four and a half LIM domains protein 5	2		-	-	3.9
252	Ci-Fhl1/2/3 protein	2		-	-	10.1
264	Ttx-3	2		-	-	0.0
261	Putative lim domain binding protein ldb1/nli/clim	2		-	-	1.5
243	Uncharacterized protein	2		-	-	0.0
275	LIM and senescent cell antigen-like-containing domain protein 1	2		-	-	0.0
240	LIM domain protein	2		-	-	16.7
237	Uncharacterized protein	2		-	-	1.7
259	Uncharacterized protein	2		-	-	0.0
334	Predicted protein	1		-	-	0.0
322	Paxillin-B	1		-	-	0.0
338	Uncharacterized protein	1		-	-	0.0
326	Uncharacterized protein	1		-	-	0.0
318	Uncharacterized protein	1		-	-	0.0
314	Uncharacterized protein	1		-	-	0.0
311	Chromosome 21, whole genome shotgun sequence	1		-	-	0.0
346	Uncharacterized protein	1		-	-	0.0
355	Four and a half LIM domains 5	1		-	-	0.0
342	Uncharacterized protein	1		-	-	0.0
331	Uncharacterized protein	1		-	-	0.0
349	Uncharacterized protein	1		-	-	0.0
301	Uncharacterized protein	1		-	-	0.0
287	Predicted protein	1		-	-	0.0
304	Predicted protein	1		-	-	0.0
308	Uncharacterized protein	1		-	-	0.0
297	Uncharacterized protein	1		-	-	0.0
329	LIM protein	1		-	-	0.0
353	AGAP008979-PA	1		-	-	0.0
350	AGAP008979-PA	1		-	-	0.0
290	Uncharacterized protein	1		-	-	0.0
306	LIM domain-containing protein, putative	1		-	-	0.0
319	LIM and senescent cell antigen-like-containing domain protein 2	1		-	-	0.0
302	Uncharacterized protein	1		-	-	0.0
293	Probable Rho-type GTPase-activating protein 3	1		-	-	0.0
360	Uncharacterized protein	1		-	-	0.0
357	LIM domain-containing protein	1		-	-	0.0
339	LIM and SH3 domain protein 1	1		-	-	0.0
344	Uncharacterized protein	1		-	-	0.0
348	Uncharacterized protein	1		-	-	0.0
295	Uncharacterized protein	1		-	-	0.0
321	Uncharacterized protein	1		-	-	0.0
328	Uncharacterized protein	1		-	-	0.0
336	Metalloprotease	1		-	-	0.0
332	Uncharacterized protein	1		-	-	0.0
324	Protein CBR-LIM-9	1		-	-	0.0
312	Uncharacterized protein	1		-	-	0.0
309	Uncharacterized protein	1		-	-	0.0
316	Uncharacterized protein	1		-	-	0.0
341	LIM and SH3 protein 1	1		-	-	0.0
340	Uncharacterized protein	1		-	-	0.0
343	Protein DA1-related 2	1		-	-	0.0
317	Uncharacterized protein	1		-	-	0.0
359	Uncharacterized protein	1		-	-	0.0
323	Uncharacterized protein	1		-	-	0.0
320	Uncharacterized protein	1		-	-	0.0
337	Uncharacterized protein	1		-	-	0.0
345	Uncharacterized protein	1		-	-	0.0
352	LIM homeobox 3	1		-	-	0.0
356	Uncharacterized protein	1		-	-	0.0
294	Probable Rho-type GTPase-activating protein 4	1		-	-	0.0
298	LIM domain-containing protein F	1		-	-	0.0
307	Uncharacterized protein	1		-	-	0.0
288	Uncharacterized protein	1		-	-	0.0
325	AGAP012744-PA	1		-	-	0.0
291	Predicted protein	1		-	-	0.0
361	Uncharacterized protein	1		-	-	0.0
335	Uncharacterized protein	1		-	-	0.0
286	Uncharacterized protein	1		-	-	0.0
351	Uncharacterized protein	1		-	-	0.0
315	Uncharacterized protein	1		-	-	0.0
358	LIM domain-binding protein 3-like	1		-	-	0.0
362	Uncharacterized protein	1		-	-	0.0
354	ISL LIM homeobox 2	1		-	-	0.0
300	Uncharacterized protein	1		-	-	0.0
296	Uncharacterized protein	1		-	-	0.0
303	Zyxin	1		-	-	0.0
292	Uncharacterized protein	1		-	-	0.0
313	Uncharacterized protein	1		-	-	0.0
299	Uncharacterized protein	1		-	-	0.0
310	Uncharacterized protein	1		-	-	0.0
330	Uncharacterized protein	1		-	-	0.0
327	Predicted protein	1		-	-	0.0
333	Uncharacterized protein	1		-	-	0.0
305	Predicted protein	1		-	-	0.0
289	Uncharacterized protein	1		-	-	0.0
347	Uncharacterized protein	1		-	-	0.0

Network disruptions

CATH Superfamily 2.10.110.10

Cysteine Rich Protein

Functional Families

Browse Functional Families