View in Gene3D

CATH Superfamily 1.25.40.180

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
Eukaryotic translation initiation factor 4 gamma, 3, putative
932
3D
 1hu3A00 - 84.2
2
Eukaryotic translation initiation factor 4 gamma, 3, putative
730
3D
 1ug3B02 - 92.9
3
Putative eukaryotic translation initiation factor 4 gamma 1
631
3D
 1ug3B01 - 91.3
4
pre-mRNA-splicing factor CWC22 homolog
565
3D
 4c9bB00 - 96.5
5
Ccr4-not transcription complex subunit 1 isoform
408
3D
 5anrA00 - 80.6
6
Basic leucine zipper and W2 domain-containing protein 1
380 - - 94.2
8
Programmed cell death protein 4
329
3D
 3eiqC02 - 89.2
7
Eukaryotic translation initiation factor 4 gamma 2
325
3D
 3l6aA02 - 90.5
9
programmed cell death protein 4
317
3D
 3eiqC01 - 94.8
10
Nuclear cap-binding protein subunit 1
289
3D
 6d0yC02 - 92.5
11
Eukaryotic translation initiation factor 4 gamma 2
260
3D
 4iulB00 - 72.2
12
Ccr4-Not transcription complex subunit
248
3D
 4b8cI00 - 97.3
13
Nuclear cap-binding protein subunit 1
240
3D
 1h2uB03 - 81.0
14
Putative regulator of nonsense transcripts 2
238
3D
 4cemB00 - 92.3
15
regulator of nonsense transcripts 2 isoform X1
208 - - 73.6
16
polyadenylate-binding protein-interacting protein 1 isoform X1
201
3D
 3rk6B00 - 96.0
17
Eukaryotic translation initiation factor 4 gamma 2
190
3D
 3l6aA01 - 88.2
21
Nuclear cap binding protein subunit 1
188
3D
 6d0yC01 - 57.7
18
eukaryotic translation initiation factor 5
185
3D
 2iu1A00 - 90.5
20
Eukaryotic translation initiation factor subunit
174
3D
 2vsxF01 - 96.7
19
CBP80/20-dependent translation initiation factor isoform X2
173 - - 57.6
22
Translation initiation factor eIF-2B epsilon subunit
153
3D
 3juiA00 - 97.9
23
regulator of nonsense transcripts 2 isoform X1
153
3D
 1uw4D00 - 82.6
24
Eukaryotic translation initiation factor 4G
139 - - 72.5
25
MIF4G domain containing a
124
3D
 4jhkA00 - 77.3
26
Regulator of nonsense transcripts UPF2
113 - - 74.5
27
Eukaryotic translation initiation factor isoform 4G-2
106 - - 72.4
28
ARM repeat superfamily protein
91 - - 81.9
29
Nuclear cap-binding protein
87 - - 70.4
31
Eukaryotic translation initiation factor 5
78
3D
 2fulF01 - 90.9
30
Regulator of nonsense transcripts UPF2
76 - - 86.1
32
Nucleolar MIF4G domain-containing protein 1
69 - - 95.2
33
Regulator of nonsense transcripts UPF2
62 - - 64.6
34
Eukaryotic translation initiation factor 4G
59 - - 88.8
36
Eukaryotic translation initiation factor isoform 4G-2
55 - - 88.4
35
snRNA cap binding complex subunit
Gcr3
55 - - 73.2
37
Nonsense-mediated mRNA decay factor
Upf2
51 - - 90.3
38
Nuclear cap-binding protein subunit 1
48 - - 71.9
39
Uncharacterized protein, isoform B
47 - - 95.8
40
Nuclear cap-binding protein subunit 1
41 - - 82.7
41
Nuclear cap-binding protein subunit 1
41 - - 90.4
42
Eukaryotic translation initiation factor 4 gamma
36 - - 99.1
43
MIF4G domain-containing protein / MA3 domain-containing protein
34 - - 74.2
44
Eukaryotic translation initiation factor 4G1, isoform B
32 - - 51.5
45
snRNA cap binding complex subunit
Gcr3
32 - - 85.3
46
Eukaryotic translation initiation factor 5
31 - - 75.3
48
Uncharacterized protein, isoform A
29 - - 71.3
47
Nonsense-mediated mRNA decay factor
Upf2
29 - - 77.8
49
Eukaryotic translation initation factor 4 gamma, putative
26 - - 18.0
50
Nuclear protein
Sgd1
25 - - 74.3
51
MIF4G domain containing
25 - - 25.7
52
Nonsense-mediated mRNA decay factor
24 - - 85.3
53
Eukaryotic translation initiation factor 4 gamma 2
21 - - 15.8
54
MIF4G domain containing
21 - - 10.3
55
Uncharacterized protein
19 - - 10.1
56
Sto1p
18 - - 57.9
58
Cell cycle control protein
18 - - 6.4
57
Initiation Factor 4G
eIF4G
18 - - 88.1
61
Eukaryotic translation initiation factor 4 gamma 2
17 - - 76.0
60
Putative CCR4-NOT transcription complex subunit 1
17 - - 7.1
59
Putative eukaryotic translation initiation factor 5
17 - - 8.8
62
CCR4-not transcription complex, putative
16 - - 69.9
68
Eukaryotic translation initiation factor 4 gamma 1-like Protein
14 - - 87.8
63
Unplaced genomic scaffold supercont1.20, whole genome shotgun sequence
14 - - 67.6
64
Translation initiation factor 4G
14 - - 92.4
65
Nuclear cap-binding protein subunit 1-B
14 - - 17.4
66
Eukaryotic translation initiation factor
14 - - 14.8
67
Eukaryotic translation initiation factor 5
14 - - 73.8
69
Uncharacterized protein
13 - - 0.9
70
Nuclear cap-binding protein complex subunit 1
12 - - 37.1
71
Eukaryotic translation initiation factor 4 gamma
12 - - 12.2
72
Uncharacterized protein
12 - - 0.8
78
Translation initiation factor eIF-2B epsilon subunit, putative
11 - - 13.3
81
Nonsense-mediated mRNA decay protein 2
11
3D
 4lunU00 - 81.8
76
Unplaced genomic scaffold supercont1.2, whole genome shotgun sequence
11 - - 6.5
77
Unplaced genomic scaffold supercont2.8, whole genome shotgun sequence
11 - - 16.0
74
Unplaced genomic scaffold supercont1.20, whole genome shotgun sequence
11 - - 13.1
75
SGD1p nuclear protein
11 - - 31.7
73
Unplaced genomic scaffold supercont2.22, whole genome shotgun sequence
11 - - 72.0
80
Chromosome 9, whole genome shotgun sequence
10 - - 94.2
82
Uncharacterized protein, isoform A
10 - - 13.8
84
Unplaced genomic scaffold supercont1.14, whole genome shotgun sequence
10 - - 13.0
79
Related to cap binding protein 80
Cbp80
10 - - 66.0
83
Uncharacterized protein, isoform B
10 - - 8.5
85
Eukaryotic translation initiation factor 4G2, isoform A
9 - - 10.5
86
Eukaryotic initiation factor 4a, putative
9 - - 37.2
87
Putative eukaryotic translation initation factor 4 gamma
9 - - 33.2
89
Nuclear cap-binding protein complex subunit 1
8 - - 1.3
91
Eukaryotic translation initiation factor 5
8 - - 71.5
92
SD07232p
8 - - 50.3
90
eIF5-mimic protein
8 - - 16.3
93
Non-muscle caldesmon, putative
8 - - 68.8
88
Eukaryotic translation initiation factor 4G2, isoform A
8 - - 17.5
99
Uncharacterized protein
7 - - 5.1
102
GM11217
7 - - 12.8
100
Pre-mRNA-splicing factor cwc22, putative
7 - - 7.5
103
nuclear cap-binding protein subunit 1-A-like
7 - - 62.1
101
Pre-mRNA-splicing factor CWC22
7 - - 0.4
96
Pre-mRNA-splicing factor CWC22, putative
7 - - 33.0
94
Nonsense-mediated mRNA decay protein 2
7 - - 2.5
95
Nuclear cap binding protein subunit 1
7 - - 16.3
98
MA3 domain containing protein
7 - - 5.4
97
Uncharacterized protein
7 - - 7.6
112
Eukaryotic translation initiation factor 4E-binding protein Mextli homolog
6 - - 73.0
105
Uncharacterized protein, isoform A
6 - - 14.4
111
Sugar 1-phosphate guanyl transferase, putative
6 - - 9.3
113
Uncharacterized protein
6 - - 68.5
110
Uncharacterized protein
6 - - 10.8
108
MIF4G domain-containing protein A
6 - - 12.9
109
Predicted protein
6 - - 24.4
106
Translation initiation factor 4G
6 - - 8.4
107
Protein CBG19247
6 - - 6.5
104
Nonsense-mediated mRNA decay protein 2
6 - - 32.1
119
Eukaryotic translation initiation factor eif-5, putative
5 - - 0.0
118
Uncharacterized protein
5 - - 0.4
116
Putative eukaryotic initiation factor 4a
5 - - 37.7
117
eIF4-gamma/eIF5/eIF2b-epsilon initiation factor, C-terminal domain
5 - - 8.5
120
Translation initiation factor eif-2b epsilon subunit
5 - - 6.4
121
Eukaryotic Initiation Factor
5 - - 85.9
115
Protein CBR-SMG-3
5 - - 51.4
114
Protein CBR-SMG-3
5 - - 46.3
128
MA3_domain_containing_protein_-_putative
4 - - 9.5
132
Predicted protein
4 - - 19.5
129
Putative eukaryotic initiation factor 4a
4 - - 3.1
124
Protein CBG18870
4 - - 15.4
131
4 - - 0.0
125
Putative eukaryotic translation initiation factor 4 gamma
4 - - 9.1
126
Zinc finger CCCH domain-containing protein 43
4 - - 2.9
133
Eukaryotic translation initiation factor 5, putative
4 - - 13.9
134
Nuclear cap-binding protein subunit 1-B
4 - - 77.7
127
Polyadenylate-binding protein-interacting protein 1, putative
4 - - 4.1
136
Eukaryotic initiation factor
4 - - 72.4
135
4 - - 69.7
130
Eukaryotic translation initiation factor
4 - - 78.7
122
CaGCR3 protein
4 - - 4.7
123
CaGCR3 protein
4 - - 6.7
142
3 - - 24.8
149
Uncharacterized protein
3 - - 14.5
139
Eukaryotic translation initiation factor 4 gamma 1-like Protein
3 - - 0.0
148
Uncharacterized protein
3 - - 36.9
141
AGAP002502-PA
3 - - 5.2
144
3 - - 24.0
143
3 - - 20.7
153
Uncharacterized protein
3 - - 42.1
137
MIF4G domain containing protein
3 - - 77.8
154
3 - - 47.6
147
Suppressor of glycerol defect protein, putative
3 - - 5.7
145
Uncharacterized protein
3 - - 24.9
152
Uncharacterized protein
3 - - 43.7
146
Uncharacterized protein
3 - - 0.0
151
Initiation factor eIF-4 gamma MA3
3 - - 49.4
138
Nuclear cap-binding protein subunit 1
3 - - 13.8
140
Putative eukaryotic translation initiation factor 4 gamma 3
3 - - 2.3
150
3 - - 61.1
191
2 - - 0.0
170
YALI0A13101p
2 - - 0.0
225
2 - - 36.3
207
2 - - 2.6
184
2 - - 42.2
181
mRNA cap-binding protein
2 - - 0.0
222
2 - - 10.0
217
2 - - 1.3
158
2 - - 13.6
165
2 - - 0.0
209
2 - - 14.6
168
2 - - 0.0
178
2 - - 1.5
224
2 - - 34.4
192
Pre-mRNA-splicing factor CWC22
2 - - 4.6
199
2 - - 0.0
183
2 - - 14.7
157
2 - - 14.0
204
2 - - 1.7
179
Uncharacterized protein
2 - - 0.0
193
Pre-mRNA-splicing factor CWC22
2 - - 0.0
177
2 - - 0.0
205
2 - - 0.0
227
2 - - 42.5
163
2 - - 0.0
214
2 - - 8.4
186
Uncharacterized protein
2 - - 23.4
156
MIF4G domain containing protein
2 - - 35.6
196
Nuclear cap-binding protein subunit 1-like Protein
2 - - 39.2
194
Uncharacterized protein
2 - - 0.0
226
Uncharacterized protein
2 - - 38.7
171
2 - - 0.0
176
nuclear cap-binding protein subunit 1-A-like
2 - - 1.8
215
2 - - 0.0
166
2 - - 1.6
185
2 - - 40.7
180
YALI0E24629p
2 - - 0.0
187
MA3 domain containing protein, putative
2 - - 0.0
212
2 - - 21.4
155
Nonsense-mediated mRNA decay protein 2
2 - - 36.4
175
2 - - 0.0
198
2 - - 0.0
202
2 - - 10.4
210
2 - - 0.0
213
2 - - 0.6
200
2 - - 5.1
161
Predicted protein
2 - - 11.1
195
YALI0D16313p
2 - - 0.0
174
2 - - 0.0
188
2 - - 0.0
203
2 - - 2.9
228
2 - - 12.5
164
2 - - 4.5
211
2 - - 0.0
218
2 - - 17.1
160
2 - - 13.6
189
2 - - 0.5
221
2 - - 47.5
182
Uncharacterized protein
2 - - 0.0
167
2 - - 4.5
173
2 - - 0.0
219
2 - - 37.2
206
2 - - 5.2
220
2 - - 39.7
197
2 - - 31.3
208
2 - - 0.0
159
Uncharacterized protein
2 - - 21.1
162
YALI0E24629p
2 - - 0.0
201
2 - - 1.4
169
2 - - 6.5
190
2 - - 0.0
172
2 - - 0.0
223
2 - - 26.9
216
2 - - 0.0
350
1 - - 0.0
311
1 - - 0.0
272
1 - - 0.0
294
1 - - 0.0
262
1 - - 0.0
232
1 - - 0.0
278
1 - - 0.0
326
1 - - 0.0
335
1 - - 0.0
305
1 - - 0.0
281
1 - - 0.0
319
1 - - 0.0
344
1 - - 0.0
336
1 - - 0.0
252
1 - - 0.0
351
1 - - 0.0
329
1 - - 0.0
346
1 - - 0.0
279
1 - - 0.0
263
1 - - 0.0
293
1 - - 0.0
310
1 - - 0.0
267
1 - - 0.0
233
1 - - 0.0
280
1 - - 0.0
273
1 - - 0.0
334
1 - - 0.0
345
1 - - 0.0
253
1 - - 0.0
258
1 - - 0.0
318
1 - - 0.0
248
1 - - 0.0
337
1 - - 0.0
236
1 - - 0.0
234
1 - - 0.0
288
1 - - 0.0
260
1 - - 0.0
264
1 - - 0.0
259
1 - - 0.0
320
1 - - 0.0
249
1 - - 0.0
338
1 - - 0.0
328
1 - - 0.0
297
1 - - 0.0
283
1 - - 0.0
244
1 - - 0.0
295
1 - - 0.0
237
1 - - 0.0
300
1 - - 0.0
235
1 - - 0.0
265
1 - - 0.0
296
1 - - 0.0
352
1 - - 0.0
256
1 - - 0.0
270
1 - - 0.0
343
1 - - 0.0
261
1 - - 0.0
321
1 - - 0.0
282
1 - - 0.0
306
1 - - 0.0
340
1 - - 0.0
285
1 - - 0.0
246
1 - - 0.0
308
1 - - 0.0
301
1 - - 0.0
349
1 - - 0.0
323
1 - - 0.0
330
1 - - 0.0
353
1 - - 0.0
257
1 - - 0.0
307
1 - - 0.0
299
1 - - 0.0
229
1 - - 0.0
315
1 - - 0.0
317
1 - - 0.0
284
1 - - 0.0
247
1 - - 0.0
289
1 - - 0.0
290
1 - - 0.0
271
1 - - 0.0
242
1 - - 0.0
342
1 - - 0.0
341
1 - - 0.0
309
1 - - 0.0
254
1 - - 0.0
322
1 - - 0.0
354
1 - - 0.0
316
1 - - 0.0
314
1 - - 0.0
302
1 - - 0.0
298
1 - - 0.0
243
1 - - 0.0
339
1 - - 0.0
268
1 - - 0.0
238
1 - - 0.0
325
1 - - 0.0
287
1 - - 0.0
333
1 - - 0.0
255
1 - - 0.0
274
1 - - 0.0
250
1 - - 0.0
303
1 - - 0.0
276
1 - - 0.0
347
1 - - 0.0
240
1 - - 0.0
230
1 - - 0.0
239
1 - - 0.0
269
1 - - 0.0
313
1 - - 0.0
331
1 - - 0.0
348
1 - - 0.0
324
1 - - 0.0
312
1 - - 0.0
286
1 - - 0.0
275
1 - - 0.0
251
1 - - 0.0
245
1 - - 0.0
332
1 - - 0.0
292
1 - - 0.0
291
1 - - 0.0
241
1 - - 0.0
327
1 - - 0.0
266
1 - - 0.0
231
1 - - 0.0
277
1 - - 0.0
304
1 - - 0.0
CATH-Gene3D is a Global Biodata Core Resource Learn more...