The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Bromodomain-like
".
FunFam 2: Bromodomain-containing protein 4
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 28 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Lysine-acetylated histone binding GO:0070577
Interacting selectively and non-covalently with a histone in which a lysine residue has been modified by acetylation.
|
17 |
D4A7T3 (/ISS)
F1QW93 (/ISS)
F1R5H6 (/ISS)
F7DRV9 (/ISS)
Q08D75 (/ISS)
Q08D75 (/ISS)
Q32S26 (/ISS)
Q4R8Y1 (/ISS)
Q58F21 (/ISS)
Q5TJG6 (/ISS)
(7 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
11 |
D4A7T3 (/IPI)
O60885 (/IPI)
O60885 (/IPI)
P25440 (/IPI)
P25440 (/IPI)
P25440 (/IPI)
Q15059 (/IPI)
Q15059 (/IPI)
Q91Y44 (/IPI)
Q95Y80 (/IPI)
(1 more) |
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
10 | F1R5H6 (/IDA) O60885 (/IDA) O60885 (/IDA) P25440 (/IDA) P25440 (/IDA) P25440 (/IDA) Q15059 (/IDA) Q15059 (/IDA) Q9ESU6 (/IDA) Q9VCG6 (/IDA) |
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
8 | Q08D75 (/ISS) Q08D75 (/ISS) Q32S26 (/ISS) Q5TJG6 (/ISS) Q6DFF2 (/ISS) Q6MGA9 (/ISS) Q7JJ13 (/ISS) Q7JJ13 (/ISS) |
|
Lysine-acetylated histone binding GO:0070577
Interacting selectively and non-covalently with a histone in which a lysine residue has been modified by acetylation.
|
8 | O60885 (/IDA) O60885 (/IDA) P25440 (/IDA) P25440 (/IDA) P25440 (/IDA) Q15059 (/IDA) Q15059 (/IDA) Q95Y80 (/IDA) |
|
P53 binding GO:0002039
Interacting selectively and non-covalently with one of the p53 family of proteins.
|
5 | F1R5H6 (/ISS) Q08D75 (/ISS) Q08D75 (/ISS) Q6DFF2 (/ISS) Q9ESU6 (/ISS) |
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
4 | Q7JJ13 (/ISO) Q7JJ13 (/ISO) Q8K2F0 (/ISO) Q8K2F0 (/ISO) |
|
Lysine-acetylated histone binding GO:0070577
Interacting selectively and non-covalently with a histone in which a lysine residue has been modified by acetylation.
|
4 | Q7JJ13 (/ISO) Q7JJ13 (/ISO) Q8K2F0 (/ISO) Q8K2F0 (/ISO) |
|
RNA polymerase II CTD heptapeptide repeat kinase activity GO:0008353
Catalysis of the reaction: ATP + (DNA-directed RNA polymerase II) = ADP + phospho-(DNA-directed RNA polymerase II); phosphorylation occurs on residues in the carboxy-terminal domain (CTD) repeats.
|
3 | O60885 (/IMP) O60885 (/IMP) Q9ESU6 (/IMP) |
|
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
|
3 | F1R5H6 (/IDA) Q58F21 (/IDA) Q91Y44 (/IDA) |
|
Transcription regulator recruiting activity GO:0001134
The function of binding to an RNA polymerase (RNAP) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation.
|
2 | O60885 (/IMP) O60885 (/IMP) |
|
P53 binding GO:0002039
Interacting selectively and non-covalently with one of the p53 family of proteins.
|
2 | O60885 (/IDA) O60885 (/IDA) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
2 | O60885 (/IPI) O60885 (/IPI) |
|
Lysine-acetylated histone binding GO:0070577
Interacting selectively and non-covalently with a histone in which a lysine residue has been modified by acetylation.
|
2 | Q91Y44 (/IMP) Q95Y80 (/IMP) |
|
RNA polymerase II C-terminal domain binding GO:0099122
Interacting selectively and non-covalently with the C-terminal domain (CTD) of the largest subunit of RNA polymerase II. The CTD is comprised of repeats of a heptapeptide with the consensus sequence YSPTSPS. The number of repeats varies with the species and a minimum number of repeats is required for RNAP II function.
|
2 | O60885 (/IDA) O60885 (/IDA) |
|
P-TEFb complex binding GO:0106140
Interacting selectively and non-covalently with the P-TEFb complex.
|
2 | O60885 (/IDA) O60885 (/IDA) |
|
Transcription regulator recruiting activity GO:0001134
The function of binding to an RNA polymerase (RNAP) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation.
|
1 | Q9ESU6 (/ISS) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | Q9ESU6 (/IDA) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
1 | Q58F21 (/TAS) |
|
RNA polymerase II CTD heptapeptide repeat kinase activity GO:0008353
Catalysis of the reaction: ATP + (DNA-directed RNA polymerase II) = ADP + phospho-(DNA-directed RNA polymerase II); phosphorylation occurs on residues in the carboxy-terminal domain (CTD) repeats.
|
1 | Q9ESU6 (/IDA) |
|
RNA polymerase II CTD heptapeptide repeat kinase activity GO:0008353
Catalysis of the reaction: ATP + (DNA-directed RNA polymerase II) = ADP + phospho-(DNA-directed RNA polymerase II); phosphorylation occurs on residues in the carboxy-terminal domain (CTD) repeats.
|
1 | Q9ESU6 (/ISO) |
|
SUMO binding GO:0032183
Interacting selectively and non-covalently with the small ubiquitin-like protein SUMO.
|
1 | Q95Y80 (/IPI) |
|
GTP-dependent protein kinase activity GO:0034211
Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of GTP.
|
1 | Q9ESU6 (/IDA) |
|
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
|
1 | Q91Y44 (/ISO) |
|
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
|
1 | Q4R8Y1 (/ISS) |
|
Lysine-acetylated histone binding GO:0070577
Interacting selectively and non-covalently with a histone in which a lysine residue has been modified by acetylation.
|
1 | F1R5H6 (/TAS) |
|
RNA polymerase II C-terminal domain binding GO:0099122
Interacting selectively and non-covalently with the C-terminal domain (CTD) of the largest subunit of RNA polymerase II. The CTD is comprised of repeats of a heptapeptide with the consensus sequence YSPTSPS. The number of repeats varies with the species and a minimum number of repeats is required for RNAP II function.
|
1 | Q9ESU6 (/IPI) |
|
RNA polymerase II C-terminal domain binding GO:0099122
Interacting selectively and non-covalently with the C-terminal domain (CTD) of the largest subunit of RNA polymerase II. The CTD is comprised of repeats of a heptapeptide with the consensus sequence YSPTSPS. The number of repeats varies with the species and a minimum number of repeats is required for RNAP II function.
|
1 | Q9ESU6 (/ISO) |
There are 75 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Thrombocyte differentiation GO:0002574
The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis.
|
20 |
A8CYQ7 (/IMP)
A8CYR1 (/IMP)
A8CYR7 (/IMP)
E7F3R5 (/IMP)
E7F3R5 (/IMP)
F1QQP6 (/IMP)
F1R5H6 (/IMP)
F8W2E9 (/IMP)
F8W3C9 (/IMP)
I3ISU1 (/IMP)
(10 more) |
|
Spinal cord development GO:0021510
The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.
|
7 | A8CYQ7 (/IMP) A8CYR1 (/IMP) I3ISU1 (/IMP) Q1LWX7 (/IMP) Q7ZVG9 (/IMP) Q7ZVG9 (/IMP) Q8AWX9 (/IMP) |
|
Hindbrain development GO:0030902
The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium).
|
7 | A8CYQ7 (/IMP) A8CYR1 (/IMP) I3ISU1 (/IMP) Q1LWX7 (/IMP) Q7ZVG9 (/IMP) Q7ZVG9 (/IMP) Q8AWX9 (/IMP) |
|
Midbrain-hindbrain boundary development GO:0030917
The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages.
|
7 | A8CYQ7 (/IMP) A8CYR1 (/IMP) I3ISU1 (/IMP) Q1LWX7 (/IMP) Q7ZVG9 (/IMP) Q7ZVG9 (/IMP) Q8AWX9 (/IMP) |
|
Regulation of apoptotic process GO:0042981
Any process that modulates the occurrence or rate of cell death by apoptotic process.
|
7 | A8CYQ7 (/IMP) A8CYR1 (/IMP) I3ISU1 (/IMP) Q1LWX7 (/IMP) Q7ZVG9 (/IMP) Q7ZVG9 (/IMP) Q8AWX9 (/IMP) |
|
Positive regulation of transcription elongation from RNA polymerase II promoter GO:0032968
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
|
6 | F1R5H6 (/ISS) P13709 (/ISS) Q08D75 (/ISS) Q08D75 (/ISS) Q6DFF2 (/ISS) Q9ESU6 (/ISS) |
|
Histone displacement GO:0001207
The removal of histones, including histone dimers, from nucleosomes within chromatin.
|
5 | D4A7T3 (/ISS) F1QW93 (/ISS) F7DRV9 (/ISS) Q4R8Y1 (/ISS) Q58F21 (/ISS) |
|
Nucleosome assembly GO:0006334
The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.
|
5 | Q32S26 (/ISS) Q5TJG6 (/ISS) Q6MGA9 (/ISS) Q7JJ13 (/ISS) Q7JJ13 (/ISS) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
5 | P25440 (/IDA) P25440 (/IDA) P25440 (/IDA) Q15059 (/IDA) Q15059 (/IDA) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
5 | Q32S26 (/ISS) Q5TJG6 (/ISS) Q6MGA9 (/ISS) Q7JJ13 (/ISS) Q7JJ13 (/ISS) |
|
Male meiotic nuclear division GO:0007140
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.
|
5 | D4A7T3 (/ISS) F1QW93 (/ISS) F7DRV9 (/ISS) Q4R8Y1 (/ISS) Q58F21 (/ISS) |
|
Male meiosis I GO:0007141
A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline.
|
5 | D4A7T3 (/ISS) F1QW93 (/ISS) F7DRV9 (/ISS) Q4R8Y1 (/ISS) Q58F21 (/ISS) |
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
5 | D4A7T3 (/ISS) F1QW93 (/ISS) F7DRV9 (/ISS) Q4R8Y1 (/ISS) Q58F21 (/ISS) |
|
Positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
|
5 | F1R5H6 (/ISS) Q08D75 (/ISS) Q08D75 (/ISS) Q6DFF2 (/ISS) Q9ESU6 (/ISS) |
|
Regulation of RNA splicing GO:0043484
Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
|
5 | D4A7T3 (/ISS) F1QW93 (/ISS) F7DRV9 (/ISS) Q4R8Y1 (/ISS) Q58F21 (/ISS) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
5 | F1R5H6 (/ISS) Q08D75 (/ISS) Q08D75 (/ISS) Q6DFF2 (/ISS) Q9ESU6 (/ISS) |
|
Regulation of inflammatory response GO:0050727
Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.
|
5 | F1R5H6 (/ISS) Q08D75 (/ISS) Q08D75 (/ISS) Q6DFF2 (/ISS) Q9ESU6 (/ISS) |
|
Positive regulation of transcription involved in meiotic cell cycle GO:0051039
Any process that activates or increases the frequency, rate or extent of transcription as part of a meiotic cell cycle.
|
5 | D4A7T3 (/ISS) F1QW93 (/ISS) F7DRV9 (/ISS) Q4R8Y1 (/ISS) Q58F21 (/ISS) |
|
Regulation of phosphorylation of RNA polymerase II C-terminal domain GO:1901407
Any process that modulates the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain.
|
5 | F1R5H6 (/ISS) Q08D75 (/ISS) Q08D75 (/ISS) Q6DFF2 (/ISS) Q9ESU6 (/ISS) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
4 | Q7JJ13 (/ISO) Q7JJ13 (/ISO) Q8K2F0 (/ISO) Q8K2F0 (/ISO) |
|
Nucleosome assembly GO:0006334
The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.
|
3 | P25440 (/IMP) P25440 (/IMP) P25440 (/IMP) |
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
3 | P25440 (/TAS) P25440 (/TAS) P25440 (/TAS) |
|
Regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0000083
Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle.
|
2 | O60885 (/IMP) O60885 (/IMP) |
|
Nucleosome assembly GO:0006334
The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.
|
2 | Q7JJ13 (/ISO) Q7JJ13 (/ISO) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
2 | D4A7T3 (/IDA) Q91Y44 (/IDA) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
2 | Q4R8Y1 (/ISS) Q58F21 (/ISS) |
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
2 | Q91Y44 (/IMP) Q9VCG6 (/IMP) |
|
Positive regulation of G2/M transition of mitotic cell cycle GO:0010971
Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
|
2 | O60885 (/IMP) O60885 (/IMP) |
|
Positive regulation of transcription elongation from RNA polymerase II promoter GO:0032968
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
|
2 | O60885 (/IDA) O60885 (/IDA) |
|
Positive regulation of transcription elongation from RNA polymerase II promoter GO:0032968
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
|
2 | O60885 (/IMP) O60885 (/IMP) |
|
Positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
|
2 | O60885 (/IDA) O60885 (/IDA) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | P13709 (/IMP) Q95Y80 (/IMP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | O60885 (/IMP) O60885 (/IMP) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | O60885 (/IDA) O60885 (/IDA) |
|
Regulation of inflammatory response GO:0050727
Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.
|
2 | O60885 (/IDA) O60885 (/IDA) |
|
Regulation of phosphorylation of RNA polymerase II C-terminal domain GO:1901407
Any process that modulates the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain.
|
2 | O60885 (/IDA) O60885 (/IDA) |
|
Positive regulation of histone H3-K36 trimethylation GO:2001255
Any process that activates or increases the frequency, rate or extent of histone H3-K36 trimethylation.
|
2 | O60885 (/IMP) O60885 (/IMP) |
|
Regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0000083
Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle.
|
1 | Q9ESU6 (/ISO) |
|
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
|
1 | Q9VCG6 (/IC) |
|
Histone displacement GO:0001207
The removal of histones, including histone dimers, from nucleosomes within chromatin.
|
1 | Q91Y44 (/IMP) |
|
Cell fate specification GO:0001708
The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
|
1 | Q95Y80 (/IGI) |
|
Inner cell mass cell proliferation GO:0001833
The proliferation of cells in the inner cell mass.
|
1 | Q9ESU6 (/IMP) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
1 | Q91Y44 (/ISO) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q58F21 (/IMP) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q91Y44 (/ISO) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | Q95Y80 (/IMP) |
|
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
1 | Q9ESU6 (/IPI) |
|
Chromosome segregation GO:0007059
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
|
1 | Q9ESU6 (/IMP) |
|
Male meiotic nuclear division GO:0007140
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.
|
1 | Q91Y44 (/IMP) |
|
Male meiosis I GO:0007141
A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline.
|
1 | Q91Y44 (/IMP) |
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
1 | D4A7T3 (/IEP) |
|
Terminal region determination GO:0007362
Specification of the terminal regions (the two non-segmented ends) of the embryo by the gap genes; exemplified in insects by the actions of huckebein and tailless gene products.
|
1 | P13709 (/IMP) |
|
Negative regulation of cell fate specification GO:0009996
Any process that restricts, stops or prevents a cell from adopting a specific cell fate.
|
1 | Q95Y80 (/IMP) |
|
Positive regulation of G2/M transition of mitotic cell cycle GO:0010971
Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
|
1 | Q9ESU6 (/ISO) |
|
Neuroblast fate specification GO:0014018
The process in which a cell becomes capable of differentiating autonomously into a neuroblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
|
1 | Q95Y80 (/IMP) |
|
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
|
1 | Q95Y80 (/IGI) |
|
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
|
1 | Q95Y80 (/IMP) |
|
Positive regulation of transcription elongation from RNA polymerase II promoter GO:0032968
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
|
1 | Q9ESU6 (/ISO) |
|
Regulation of vulval development GO:0040028
Any process that modulates the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
|
1 | Q95Y80 (/IMP) |
|
Positive regulation of DNA binding GO:0043388
Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
|
1 | Q9ESU6 (/IDA) |
|
Regulation of RNA splicing GO:0043484
Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
|
1 | Q91Y44 (/IMP) |
|
Histone H4-K12 acetylation GO:0043983
The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 12 of the histone.
|
1 | Q9ESU6 (/IMP) |
|
Histone H3-K14 acetylation GO:0044154
The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 14 of the histone.
|
1 | Q9ESU6 (/IMP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q95Y80 (/IGI) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q9ESU6 (/ISS) |
|
Muscle cell cellular homeostasis GO:0046716
The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.
|
1 | Q95Y80 (/IGI) |
|
Muscle cell cellular homeostasis GO:0046716
The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.
|
1 | Q95Y80 (/IMP) |
|
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
|
1 | Q9ESU6 (/IDA) |
|
Spermatid differentiation GO:0048515
The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
|
1 | Q9VCG6 (/IMP) |
|
Dendrite morphogenesis GO:0048813
The process in which the anatomical structures of a dendrite are generated and organized.
|
1 | P13709 (/IMP) |
|
Positive regulation of transcription involved in meiotic cell cycle GO:0051039
Any process that activates or increases the frequency, rate or extent of transcription as part of a meiotic cell cycle.
|
1 | Q91Y44 (/IMP) |
|
Protein localization to chromatin GO:0071168
Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin.
|
1 | Q95Y80 (/IMP) |
|
Multicellular organismal locomotion GO:0071965
Locomotion in a multicellular organism, i.e. self-propelled movement of a multicellular organism from one location to another.
|
1 | Q95Y80 (/IGI) |
|
Multicellular organismal locomotion GO:0071965
Locomotion in a multicellular organism, i.e. self-propelled movement of a multicellular organism from one location to another.
|
1 | Q95Y80 (/IMP) |
|
Positive regulation of histone H3-K36 trimethylation GO:2001255
Any process that activates or increases the frequency, rate or extent of histone H3-K36 trimethylation.
|
1 | Q9ESU6 (/ISS) |
There are 21 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
13 |
A0A024RCR5 (/IDA)
A0A024RCR5 (/IDA)
A0A024RCR5 (/IDA)
H0Y6K2 (/IDA)
H0Y799 (/IDA)
O60885 (/IDA)
O60885 (/IDA)
P25440 (/IDA)
P25440 (/IDA)
P25440 (/IDA)
(3 more) |
|
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
11 |
A0A024RCR5 (/IDA)
A0A024RCR5 (/IDA)
A0A024RCR5 (/IDA)
H0Y6K2 (/IDA)
H0Y799 (/IDA)
P25440 (/IDA)
P25440 (/IDA)
P25440 (/IDA)
U3KQA6 (/IDA)
U3KQA6 (/IDA)
(1 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
10 | D4A7T3 (/IDA) F1R5H6 (/IDA) O60885 (/IDA) O60885 (/IDA) P13709 (/IDA) Q7JJ13 (/IDA) Q7JJ13 (/IDA) Q91Y44 (/IDA) Q95Y80 (/IDA) Q9ESU6 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
8 | D4A7T3 (/ISS) F1QW93 (/ISS) F7DRV9 (/ISS) Q08D75 (/ISS) Q08D75 (/ISS) Q4R8Y1 (/ISS) Q58F21 (/ISS) Q6DFF2 (/ISS) |
|
Condensed nuclear chromosome GO:0000794
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome.
|
3 | O60885 (/IDA) O60885 (/IDA) Q9ESU6 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
3 | P25440 (/TAS) P25440 (/TAS) P25440 (/TAS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | Q7JJ13 (/ISO) Q7JJ13 (/ISO) |
|
Chromosome GO:0005694
A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
|
2 | Q95Y80 (/IDA) Q9VCG6 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q7JJ13 (/IDA) Q7JJ13 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | O60885 (/IDA) O60885 (/IDA) |
|
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
2 | Q7JJ13 (/ISO) Q7JJ13 (/ISO) |
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
1 | Q9ESU6 (/IDA) |
|
Condensed chromosome GO:0000793
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.
|
1 | F1R5H6 (/IDA) |
|
Condensed nuclear chromosome GO:0000794
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome.
|
1 | Q9ESU6 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P13709 (/HDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q91Y44 (/ISO) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | Q9VCG6 (/IDA) |
|
Cyclin/CDK positive transcription elongation factor complex GO:0008024
A transcription elongation factor complex that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme. Contains a cyclin and a cyclin-dependent protein kinase catalytic subunit.
|
1 | Q9ESU6 (/IDA) |
|
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
|
1 | Q9VCG6 (/IDA) |
|
Metaphase plate GO:0070090
The intracellular plane, located halfway between the poles of the spindle, where chromosomes align during metaphase of mitotic or meiotic nuclear division.
|
1 | Q95Y80 (/IDA) |
|
Precatalytic spliceosome GO:0071011
A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs.
|
1 | Q9VCG6 (/HDA) |
