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CATH Superfamily 1.20.80.10

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Talin 2Krev interaction trapped protein 1acyl-CoA-binding domain-containing protein 6 isoform X1Enoyl-CoA delta isomerase 2, mitochondrialErythrocyte membrane protein band 4.1radixin isoform X1Tyrosine-protein phosphatase non-receptor type 4Protein-tyrosine kinase 2-beta isoform 1FERM, RhoGEF and pleckstrin domain-containing protein 1FERM domain-containing protein 5 isoform X1FERM domain containing 4AFERM and PDZ domain containing 4Acyl-CoA-binding domain-containing protein 5Tyrosine-protein phosphatase non-receptor type 13Myosin VIIAUnconventional myosin-VIIaTyrosine-protein phosphatase non-receptor typeFERM domain-containing protein 6 isoform X2Golgi resident protein GCP60Kinesin-like calmodulin binding proteinE3 ubiquitin-protein ligase MYLIPUnconventional myosin-Xpleckstrin homology domain-containing family H member 2FERM domain containing 8acyl-CoA-binding domain-containing protein 4 isoform X1pleckstrin homology domain-containing family H member 3 isoform X2Uncharacterized protein, isoform BFocal adhesion kinase, isoform DUncharacterized protein, isoform APez, isoform AFERM domain (Protein4.1-ezrin-radixin-moesin) familyFERM domain-containing proteinRIC1 proteinBlast:E3 ubiquitin-protein ligase MYLIP-AInactive tyrosine-protein kinase kin-32FERM domain (Protein4.1-ezrin-radixin-moesin) familyE3 ubiquitin-protein ligase MYLIP-AMyosin 28B1, isoform BMyosin 28B1, isoform BAcyl-CoA-binding domain-containing protein 2TaLiNdiazepam-binding inhibitor-like 5Protein expandedMotor AXon guidanceKinesin-like calmodulin binding proteinProtein CBG13772Tyrosine-protein phosphataseAcyl-CoA binding domain containing 3Predicted proteinAutophagy-related protein 37Acyl CoA binding protein family (AFU_orthologue AFUA_2G11060)Acyl-CoA-binding domain 3Putative acyl-CoA binding proteinAcyl-CoA-binding domain-containing protein 4FERM, ARHGEF and pleckstrin domain-containing protein 1band 4.1-like protein 4 isoform X1Band 4.1-like protein 5Uncharacterized proteinAcyl-CoA binding protein, putativeAcyl CoA binding protein, putativeAcyl-CoA binding protein, putativeUncharacterized proteinPredicted proteinUncharacterized proteinGolgi resident protein GCP60Golgi resident protein GCP60Fermitin 2Enoyl-CoA delta isomerase 3, peroxisomalUncharacterized proteinE3 ubiquitin-protein ligase MYLIPUncharacterized proteinUncharacterized proteinFERM domain-containing 4BaPredicted proteinUncharacterized proteinUncharacterized proteinMyosin-I heavy chainPredicted proteinUncharacterized proteinProtein tyrosine kinase 2 betaUncharacterized proteinPredicted proteinMyosin-G heavy chain
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FunFam 23: FERM domain containing 8

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 1 Q9BZ67 (/IPI)
Showing 1 to 1 of 1 entries

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Positive regulation of tumor necrosis factor secretion GO:1904469
Any process that activates or increases the frequency, rate or extent of tumor necrosis factor secretion.
 5 Q0IJ35 (/ISS) Q3UFK8 (/ISS) Q5U2R3 (/ISS) Q7ZWP1 (/ISS) Q7ZWP1 (/ISS)
Anterior/posterior pattern specification GO:0009952
The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
 1 E7F221 (/IGI)
Negative regulation of Wnt signaling pathway GO:0030178
Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway.
 1 E7F221 (/IGI)
Regulation of canonical Wnt signaling pathway GO:0060828
Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
 1 E7F221 (/IGI)
Positive regulation of tumor necrosis factor secretion GO:1904469
Any process that activates or increases the frequency, rate or extent of tumor necrosis factor secretion.
 1 Q9BZ67 (/IDA)
Positive regulation of tumor necrosis factor secretion GO:1904469
Any process that activates or increases the frequency, rate or extent of tumor necrosis factor secretion.
 1 Q9BZ67 (/IMP)
Positive regulation of tumor necrosis factor secretion GO:1904469
Any process that activates or increases the frequency, rate or extent of tumor necrosis factor secretion.
 1 Q3UFK8 (/ISO)
Showing 1 to 7 of 7 entries

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 5 Q0IJ35 (/ISS) Q3UFK8 (/ISS) Q5U2R3 (/ISS) Q7ZWP1 (/ISS) Q7ZWP1 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 5 Q0IJ35 (/ISS) Q3UFK8 (/ISS) Q5U2R3 (/ISS) Q7ZWP1 (/ISS) Q7ZWP1 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 1 Q9BZ67 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 1 Q3UFK8 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 1 Q9BZ67 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 1 Q3UFK8 (/ISO)
Showing 1 to 6 of 6 entries
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