The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 227: Karst, isoform C

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
6 A8JNJ6 (/IDA) M9PBL6 (/IDA) Q7KV69 (/IDA) Q7KV70 (/IDA) Q99140 (/IDA) Q9VZQ3 (/IDA)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
6 A8JNJ6 (/ISS) M9PBL6 (/ISS) Q7KV69 (/ISS) Q7KV70 (/ISS) Q99140 (/ISS) Q9VZQ3 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
6 A8JNJ6 (/IPI) M9PBL6 (/IPI) Q7KV69 (/IPI) Q7KV70 (/IPI) Q99140 (/IPI) Q9VZQ3 (/IPI)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
6 A8JNJ6 (/IDA) M9PBL6 (/IDA) Q7KV69 (/IDA) Q7KV70 (/IDA) Q99140 (/IDA) Q9VZQ3 (/IDA)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
6 A8JNJ6 (/IMP) M9PBL6 (/IMP) Q7KV69 (/IMP) Q7KV70 (/IMP) Q99140 (/IMP) Q9VZQ3 (/IMP)
Plasma membrane organization GO:0007009
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane.
6 A8JNJ6 (/TAS) M9PBL6 (/TAS) Q7KV69 (/TAS) Q7KV70 (/TAS) Q99140 (/TAS) Q9VZQ3 (/TAS)
Regulation of multivesicular body size involved in endosome transport GO:0010797
Any process that modulates the volume of a multivesicular body as part of the directed movement of substances from endosomes to lysosomes or vacuoles.
6 A8JNJ6 (/IMP) M9PBL6 (/IMP) Q7KV69 (/IMP) Q7KV70 (/IMP) Q99140 (/IMP) Q9VZQ3 (/IMP)
Ovarian follicle cell development GO:0030707
The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster.
6 A8JNJ6 (/TAS) M9PBL6 (/TAS) Q7KV69 (/TAS) Q7KV70 (/TAS) Q99140 (/TAS) Q9VZQ3 (/TAS)
Endosome transport via multivesicular body sorting pathway GO:0032509
The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment.
6 A8JNJ6 (/IMP) M9PBL6 (/IMP) Q7KV69 (/IMP) Q7KV70 (/IMP) Q99140 (/IMP) Q9VZQ3 (/IMP)
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
6 A8JNJ6 (/IMP) M9PBL6 (/IMP) Q7KV69 (/IMP) Q7KV70 (/IMP) Q99140 (/IMP) Q9VZQ3 (/IMP)
Zonula adherens assembly GO:0045186
Assembly of the zonula adherens, a cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.
6 A8JNJ6 (/TAS) M9PBL6 (/TAS) Q7KV69 (/TAS) Q7KV70 (/TAS) Q99140 (/TAS) Q9VZQ3 (/TAS)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
6 A8JNJ6 (/HDA) M9PBL6 (/HDA) Q7KV69 (/HDA) Q7KV70 (/HDA) Q99140 (/HDA) Q9VZQ3 (/HDA)
Adherens junction GO:0005912
A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.
6 A8JNJ6 (/IDA) M9PBL6 (/IDA) Q7KV69 (/IDA) Q7KV70 (/IDA) Q99140 (/IDA) Q9VZQ3 (/IDA)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
6 A8JNJ6 (/IDA) M9PBL6 (/IDA) Q7KV69 (/IDA) Q7KV70 (/IDA) Q99140 (/IDA) Q9VZQ3 (/IDA)
Apicolateral plasma membrane GO:0016327
The apical end of the lateral plasma membrane of epithelial cells.
6 A8JNJ6 (/TAS) M9PBL6 (/TAS) Q7KV69 (/TAS) Q7KV70 (/TAS) Q99140 (/TAS) Q9VZQ3 (/TAS)
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