CATH Superfamily 1.20.5.20
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 1: apolipoprotein A-I
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 43 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
8 | P02647 (/IPI) P02647 (/IPI) P02647 (/IPI) P02647 (/IPI) P02647 (/IPI) P04639 (/IPI) P08250 (/IPI) Q00623 (/IPI) |
|
Amyloid-beta binding GO:0001540
Interacting selectively and non-covalently with amyloid-beta peptide/protein and/or its precursor.
|
7 | P02647 (/IPI) P02647 (/IPI) P02647 (/IPI) P02647 (/IPI) P02647 (/IPI) P04639 (/IPI) P09809 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
6 | P02647 (/IPI) P02647 (/IPI) P02647 (/IPI) P02647 (/IPI) P02647 (/IPI) Q00623 (/IPI) |
|
Amyloid-beta binding GO:0001540
Interacting selectively and non-covalently with amyloid-beta peptide/protein and/or its precursor.
|
5 | P02647 (/IDA) P02647 (/IDA) P02647 (/IDA) P02647 (/IDA) P02647 (/IDA) |
|
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
5 | P02647 (/IPI) P02647 (/IPI) P02647 (/IPI) P02647 (/IPI) P02647 (/IPI) |
|
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
|
5 | P02647 (/IDA) P02647 (/IDA) P02647 (/IDA) P02647 (/IDA) P02647 (/IDA) |
|
Cholesterol binding GO:0015485
Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
|
5 | P02647 (/IDA) P02647 (/IDA) P02647 (/IDA) P02647 (/IDA) P02647 (/IDA) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
5 | P02647 (/IPI) P02647 (/IPI) P02647 (/IPI) P02647 (/IPI) P02647 (/IPI) |
|
Heat shock protein binding GO:0031072
Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.
|
5 | P02647 (/IPI) P02647 (/IPI) P02647 (/IPI) P02647 (/IPI) P02647 (/IPI) |
|
Apolipoprotein receptor binding GO:0034190
Interacting selectively and non-covalently with an apolipoprotein receptor.
|
5 | P02647 (/IPI) P02647 (/IPI) P02647 (/IPI) P02647 (/IPI) P02647 (/IPI) |
Showing 1 to 10 of 43 entries
There are 128 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of cholesterol efflux GO:0010875
Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
|
65 |
D2HC77 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
G3QY98 (/ISS)
G3QY98 (/ISS)
(55 more) |
|
Positive regulation of phagocytosis GO:0050766
Any process that activates or increases the frequency, rate or extent of phagocytosis.
|
65 |
D2HC77 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
G3QY98 (/ISS)
G3QY98 (/ISS)
(55 more) |
|
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
|
65 |
D2HC77 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
G3QY98 (/ISS)
G3QY98 (/ISS)
(55 more) |
|
Positive regulation of phospholipid efflux GO:1902995
Any process that activates or increases the frequency, rate or extent of phospholipid efflux.
|
65 |
D2HC77 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
F7FQM7 (/ISS)
G3QY98 (/ISS)
G3QY98 (/ISS)
(55 more) |
|
Protein oxidation GO:0018158
The modification of a protein amino acid by oxidation.
|
27 |
G3QY98 (/ISS)
G3QY98 (/ISS)
G3QY98 (/ISS)
G3QY98 (/ISS)
G3QY98 (/ISS)
P02648 (/ISS)
P09809 (/ISS)
P15497 (/ISS)
P15497 (/ISS)
P18648 (/ISS)
(17 more) |
|
Peptidyl-methionine modification GO:0018206
The modification of peptidyl-methionine.
|
27 |
G3QY98 (/ISS)
G3QY98 (/ISS)
G3QY98 (/ISS)
G3QY98 (/ISS)
G3QY98 (/ISS)
P02648 (/ISS)
P09809 (/ISS)
P15497 (/ISS)
P15497 (/ISS)
P18648 (/ISS)
(17 more) |
|
Cholesterol transport GO:0030301
The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
7 | P02647 (/IDA) P02647 (/IDA) P02647 (/IDA) P02647 (/IDA) P02647 (/IDA) P04639 (/IDA) Q00623 (/IDA) |
|
Cholesterol metabolic process GO:0008203
The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.
|
6 | P02647 (/IMP) P02647 (/IMP) P02647 (/IMP) P02647 (/IMP) P02647 (/IMP) Q00623 (/IMP) |
|
Cholesterol efflux GO:0033344
The directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
|
6 | P02647 (/IDA) P02647 (/IDA) P02647 (/IDA) P02647 (/IDA) P02647 (/IDA) Q00623 (/IDA) |
|
Cholesterol efflux GO:0033344
The directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
|
6 | P02647 (/IMP) P02647 (/IMP) P02647 (/IMP) P02647 (/IMP) P02647 (/IMP) Q00623 (/IMP) |
Showing 1 to 10 of 128 entries
There are 43 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
9 | P02647 (/IDA) P02647 (/IDA) P02647 (/IDA) P02647 (/IDA) P02647 (/IDA) P04639 (/IDA) P08250 (/IDA) P18648 (/IDA) Q00623 (/IDA) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
6 | P02647 (/TAS) P02647 (/TAS) P02647 (/TAS) P02647 (/TAS) P02647 (/TAS) Q00623 (/TAS) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
6 | P02647 (/HDA) P02647 (/HDA) P02647 (/HDA) P02647 (/HDA) P02647 (/HDA) P18648 (/HDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
6 | O42364 (/ISS) P02647 (/ISS) P02647 (/ISS) P02647 (/ISS) P02647 (/ISS) P02647 (/ISS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
6 | P02647 (/TAS) P02647 (/TAS) P02647 (/TAS) P02647 (/TAS) P02647 (/TAS) Q00623 (/TAS) |
|
High-density lipoprotein particle GO:0034364
A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process.
|
6 | P02647 (/IDA) P02647 (/IDA) P02647 (/IDA) P02647 (/IDA) P02647 (/IDA) P04639 (/IDA) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
5 | P02647 (/HDA) P02647 (/HDA) P02647 (/HDA) P02647 (/HDA) P02647 (/HDA) |
|
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
|
5 | P02647 (/TAS) P02647 (/TAS) P02647 (/TAS) P02647 (/TAS) P02647 (/TAS) |
|
Endoplasmic reticulum lumen GO:0005788
The volume enclosed by the membranes of the endoplasmic reticulum.
|
5 | P02647 (/TAS) P02647 (/TAS) P02647 (/TAS) P02647 (/TAS) P02647 (/TAS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
5 | P02647 (/TAS) P02647 (/TAS) P02647 (/TAS) P02647 (/TAS) P02647 (/TAS) |
Showing 1 to 10 of 43 entries
