The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 122: Oncoprotein MEQ

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 Q6USD0 (/IPI) Q6USD0 (/IPI) Q77Q71 (/IPI) Q77Q71 (/IPI) Q80IW5 (/IPI) Q9DGW5 (/IPI) Q9DGW5 (/IPI)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
5 Q6USD0 (/IDA) Q6USD0 (/IDA) Q80IW5 (/IDA) Q9DGW5 (/IDA) Q9DGW5 (/IDA)
P53 binding GO:0002039
Interacting selectively and non-covalently with one of the p53 family of proteins.
2 Q77Q71 (/IPI) Q77Q71 (/IPI)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
2 Q9DGW5 (/IDA) Q9DGW5 (/IDA)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
2 Q9DGW5 (/TAS) Q9DGW5 (/TAS)
Hsp70 protein binding GO:0030544
Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size.
2 Q9DGW5 (/IPI) Q9DGW5 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 Q9DGW5 (/TAS) Q9DGW5 (/TAS)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 Q77Q71 (/IDA) Q77Q71 (/IDA)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
2 Q9DGW5 (/TAS) Q9DGW5 (/TAS)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
1 Q80IW5 (/IPI)

There are 19 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Modulation by virus of host transcription GO:0019056
Any process in which a virus modulates the frequency, rate or extent of its host's transcription.
5 Q6USD0 (/IDA) Q6USD0 (/IDA) Q80IW5 (/IDA) Q9DGW5 (/IDA) Q9DGW5 (/IDA)
Positive regulation of DNA-templated transcription, initiation GO:2000144
Any process that activates or increases the frequency, rate or extent of DNA-templated transcription initiation.
5 Q6USD0 (/IDA) Q6USD0 (/IDA) Q80IW5 (/IDA) Q9DGW5 (/IDA) Q9DGW5 (/IDA)
Positive regulation by symbiont of host protein levels GO:1990219
Any process in which an organism activates, maintains or increases the frequency, rate or extent of protein levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
4 Q77Q71 (/IDA) Q77Q71 (/IDA) Q9DGW5 (/IDA) Q9DGW5 (/IDA)
Modulation of transcription in other organism involved in symbiotic interaction GO:0052312
Any process in which an organism modulates the frequency, rate or extent of transcription in a second organism, where the two organisms are in a symbiotic interaction.
3 Q80IW5 (/TAS) Q9DGW5 (/TAS) Q9DGW5 (/TAS)
Suppression by virus of host apoptotic process GO:0019050
Any viral process that inhibits apoptosis of infected host cells, facilitating prolonged cell survival during viral replication.
2 Q9DGW5 (/TAS) Q9DGW5 (/TAS)
Immortalization of host cell by virus GO:0019088
A virus-induced cellular transformation arising in immortalized cells, or cells capable of indefinite replication, due to their ability to produce their own telomerase.
2 Q9DGW5 (/TAS) Q9DGW5 (/TAS)
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
2 Q77Q71 (/IMP) Q77Q71 (/IMP)
Negative regulation of viral transcription GO:0032897
Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription.
2 Q9DGW5 (/IMP) Q9DGW5 (/IMP)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
2 Q77Q71 (/IMP) Q77Q71 (/IMP)
Negative regulation by host of viral transcription GO:0043922
Any process in which a host organism stops, prevents, or reduces the frequency, rate or extent of viral transcription.
2 Q9DGW5 (/IDA) Q9DGW5 (/IDA)
Positive regulation of viral genome replication GO:0045070
Any process that activates or increases the frequency, rate or extent of viral genome replication.
2 Q77Q71 (/IDA) Q77Q71 (/IDA)
Positive regulation of viral genome replication GO:0045070
Any process that activates or increases the frequency, rate or extent of viral genome replication.
2 Q77Q71 (/IMP) Q77Q71 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 Q77Q71 (/IMP) Q77Q71 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
2 Q69306 (/IDA) Q69306 (/IDA)
Regulation by virus of viral protein levels in host cell GO:0046719
Any virus-mediated process that modulates the levels of viral proteins in a cell.
2 Q9DGW5 (/TAS) Q9DGW5 (/TAS)
Induction by symbiont of nodulation, tumor or growth in host GO:0051819
The process in which a symbiont causes the formation of a mass of cells in a host organism.
2 Q9DGW5 (/IDA) Q9DGW5 (/IDA)
Regulation of transformation of host cell by virus GO:1904187
Any process that modulates the frequency, rate or extent of transformation of host cell by virus.
2 Q77Q71 (/IMP) Q77Q71 (/IMP)
Positive regulation by symbiont of host transcription GO:1990216
Any process in which an organism activates, maintains or increases the frequency, rate or extent of transcription in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2 Q77Q71 (/IDA) Q77Q71 (/IDA)
Negative regulation of DNA-binding transcription factor activity GO:0043433
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
1 Q80IW5 (/IDA)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Host cell nucleus GO:0042025
A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
4 Q77Q71 (/IDA) Q77Q71 (/IDA) Q9DGW5 (/IDA) Q9DGW5 (/IDA)
Host cell nucleus GO:0042025
A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2 Q9DGW5 (/IMP) Q9DGW5 (/IMP)
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