CATH Superfamily 1.20.5.170
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 12: Putative transcription factor AP-1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 72 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
17 |
F1NCN0 (/IPI)
P05412 (/IPI)
P05412 (/IPI)
P05627 (/IPI)
P05627 (/IPI)
P09450 (/IPI)
P09450 (/IPI)
P09450 (/IPI)
P15066 (/IPI)
P15066 (/IPI)
(7 more) |
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
10 | P05627 (/IDA) P05627 (/IDA) P09450 (/IDA) P09450 (/IDA) P09450 (/IDA) P15066 (/IDA) P15066 (/IDA) P24898 (/IDA) P24898 (/IDA) P24898 (/IDA) |
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
9 | O77627 (/ISS) P05627 (/ISS) P05627 (/ISS) P12981 (/ISS) P17325 (/ISS) P18870 (/ISS) P54864 (/ISS) P54864 (/ISS) P56432 (/ISS) |
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
8 | P05412 (/IMP) P05412 (/IMP) P09450 (/IMP) P09450 (/IMP) P09450 (/IMP) P15066 (/IMP) P15066 (/IMP) P17325 (/IMP) |
Double-stranded DNA binding GO:0003690
Interacting selectively and non-covalently with double-stranded DNA.
|
7 | P05627 (/ISO) P05627 (/ISO) P09450 (/ISO) P09450 (/ISO) P09450 (/ISO) P15066 (/ISO) P15066 (/ISO) |
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
7 | P05627 (/ISO) P05627 (/ISO) P09450 (/ISO) P09450 (/ISO) P09450 (/ISO) P15066 (/ISO) P15066 (/ISO) |
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
7 | P05627 (/ISO) P05627 (/ISO) P09450 (/ISO) P09450 (/ISO) P09450 (/ISO) P15066 (/ISO) P15066 (/ISO) |
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
6 | P05412 (/ISA) P05412 (/ISA) P17275 (/ISA) P17275 (/ISA) P17275 (/ISA) P17535 (/ISA) |
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
6 | P05412 (/ISM) P05412 (/ISM) P17275 (/ISM) P17275 (/ISM) P17275 (/ISM) P17535 (/ISM) |
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
6 | P05412 (/NAS) P05412 (/NAS) P17275 (/NAS) P17275 (/NAS) P17275 (/NAS) P17535 (/NAS) |
Showing 1 to 10 of 72 entries
There are 157 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
11 |
P05412 (/IDA)
P05412 (/IDA)
P05627 (/IDA)
P05627 (/IDA)
P15066 (/IDA)
P15066 (/IDA)
P17275 (/IDA)
P17275 (/IDA)
P17275 (/IDA)
P17535 (/IDA)
(1 more) |
Ras protein signal transduction GO:0007265
A series of molecular signals within the cell that are mediated by a member of the Ras superfamily of proteins switching to a GTP-bound active state.
|
9 | O77627 (/ISS) P05627 (/ISS) P05627 (/ISS) P12981 (/ISS) P17325 (/ISS) P18870 (/ISS) P54864 (/ISS) P54864 (/ISS) P56432 (/ISS) |
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
|
7 | P05627 (/ISO) P05627 (/ISO) P09450 (/ISO) P09450 (/ISO) P09450 (/ISO) P15066 (/ISO) P15066 (/ISO) |
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
7 | P05627 (/ISO) P05627 (/ISO) P09450 (/ISO) P09450 (/ISO) P09450 (/ISO) P15066 (/ISO) P15066 (/ISO) |
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
7 | P05627 (/IDA) P05627 (/IDA) P09450 (/IDA) P09450 (/IDA) P09450 (/IDA) P15066 (/IDA) P15066 (/IDA) |
Lymph vessel development GO:0001945
The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure.
|
5 | A0A0R4IAV4 (/IGI) A8E7N0 (/IGI) C5IG46 (/IGI) Q7T367 (/IGI) Q7T3E3 (/IGI) |
Lymph vessel development GO:0001945
The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure.
|
5 | A0A0R4IAV4 (/IMP) A8E7N0 (/IMP) C5IG46 (/IMP) Q7T367 (/IMP) Q7T3E3 (/IMP) |
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
|
5 | P17325 (/IMP) P24898 (/IMP) P24898 (/IMP) P24898 (/IMP) P52909 (/IMP) |
Response to mechanical stimulus GO:0009612
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
|
5 | P17325 (/IEP) P24898 (/IEP) P24898 (/IEP) P24898 (/IEP) P52909 (/IEP) |
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
|
5 | P17325 (/IEP) P24898 (/IEP) P24898 (/IEP) P24898 (/IEP) P52909 (/IEP) |
Showing 1 to 10 of 157 entries
There are 23 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
14 |
P05412 (/IDA)
P05412 (/IDA)
P05627 (/IDA)
P05627 (/IDA)
P17325 (/IDA)
P17535 (/IDA)
P18289 (/IDA)
P18870 (/IDA)
P24898 (/IDA)
P24898 (/IDA)
(4 more) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
9 | P05412 (/TAS) P05412 (/TAS) P05627 (/TAS) P05627 (/TAS) P17275 (/TAS) P17275 (/TAS) P17275 (/TAS) P17535 (/TAS) P18289 (/TAS) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
8 | P05412 (/IDA) P05412 (/IDA) P17275 (/IDA) P17275 (/IDA) P17275 (/IDA) Q5U079 (/IDA) Q5U079 (/IDA) Q5U079 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
7 | P05627 (/ISO) P05627 (/ISO) P09450 (/ISO) P09450 (/ISO) P09450 (/ISO) P15066 (/ISO) P15066 (/ISO) |
Transcription factor AP-1 complex GO:0035976
A heterodimeric transcription factor complex composed of proteins from the c-Fos, c-Jun, activating transcription factor (ATF) or JDP families. The subunits contain a basic leucine zipper (bZIP) domain that is essential for dimerization and DNA binding. Jun-Fos heterodimers bind preferentially to a heptamer consensus sequence (TPA responsive element (TRE)), whereas Jun-ATF dimers bind the cyclic AMP responsive element (CRE) to regulate transcription of target genes.
|
7 | P05627 (/ISO) P05627 (/ISO) P09450 (/ISO) P09450 (/ISO) P09450 (/ISO) P15066 (/ISO) P15066 (/ISO) |
Transcription factor AP-1 complex GO:0035976
A heterodimeric transcription factor complex composed of proteins from the c-Fos, c-Jun, activating transcription factor (ATF) or JDP families. The subunits contain a basic leucine zipper (bZIP) domain that is essential for dimerization and DNA binding. Jun-Fos heterodimers bind preferentially to a heptamer consensus sequence (TPA responsive element (TRE)), whereas Jun-ATF dimers bind the cyclic AMP responsive element (CRE) to regulate transcription of target genes.
|
6 | P05412 (/IDA) P05412 (/IDA) P17275 (/IDA) P17275 (/IDA) P17275 (/IDA) P17535 (/IDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
5 | P05627 (/ISO) P05627 (/ISO) P09450 (/ISO) P09450 (/ISO) P09450 (/ISO) |
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
|
4 | P17275 (/TAS) P17275 (/TAS) P17275 (/TAS) P17535 (/TAS) |
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
|
3 | P05627 (/IPI) P05627 (/IPI) P18289 (/IPI) |
Nuclear chromosome GO:0000228
A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact.
|
2 | P05412 (/TAS) P05412 (/TAS) |
Showing 1 to 10 of 23 entries