CATH Superfamily 1.20.5.170
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 114: Tropomyosin
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Actin lateral binding GO:0003786
Interacting selectively and non-covalently with an actin filament along its length.
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1 | Q02088 (/IDA) |
Actin filament binding GO:0051015
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
|
1 | Q02088 (/IDA) |
There are 17 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Mitotic cytokinesis GO:0000281
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
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1 | Q02088 (/IMP) |
Negative regulation of actin filament depolymerization GO:0030835
Any process that stops, prevents, or reduces the frequency, rate or extent of actin depolymerization.
|
1 | Q02088 (/IDA) |
Negative regulation of actin filament polymerization GO:0030837
Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization.
|
1 | Q02088 (/IDA) |
Plasma membrane fusion involved in cytogamy GO:0032220
The joining of two or more lipid bilayer membranes that surround cells, that contributes to cytogamy.
|
1 | Q02088 (/IMP) |
Negative regulation of Arp2/3 complex-mediated actin nucleation GO:0034316
Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.
|
1 | Q02088 (/IDA) |
Actin cortical patch organization GO:0044396
A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane in cells, at sites of endocytosis.
|
1 | Q02088 (/IMP) |
Actin cortical patch localization GO:0051666
Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.
|
1 | Q02088 (/IMP) |
Positive regulation of actin filament annealing GO:0110056
Any process that activates or increases the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments.
|
1 | Q02088 (/IDA) |
Negative regulation of microfilament motor activity GO:0120080
Any process that stops, prevents or reduces the frequency, rate or extent of microfilament motor activity.
|
1 | Q02088 (/IDA) |
Positive regulation of microfilament motor activity GO:0120081
Any process that activates or increases the frequency, rate or extent of microfilament motor activity.
|
1 | Q02088 (/IDA) |
Mitotic actomyosin contractile ring contraction GO:1902404
Any actomyosin contractile ring contraction that is involved in mitotic cell cycle.
|
1 | Q02088 (/IMP) |
Mitotic actomyosin contractile ring assembly GO:1903475
Any actomyosin contractile ring assembly that is involved in mitotic cytokinesis.
|
1 | Q02088 (/IMP) |
Negative regulation of actin filament severing GO:1903919
Any process that stops, prevents or reduces the frequency, rate or extent of actin filament severing.
|
1 | Q02088 (/IDA) |
Negative regulation of actin filament binding GO:1904530
Any process that stops, prevents or reduces the frequency, rate or extent of actin filament binding.
|
1 | Q02088 (/IDA) |
Positive regulation of actin binding GO:1904618
Any process that activates or increases the frequency, rate or extent of actin binding.
|
1 | Q02088 (/IDA) |
Negative regulation of actin-dependent ATPase activity GO:1904622
Any process that stops, prevents or reduces the frequency, rate or extent of actin-dependent ATPase activity.
|
1 | Q02088 (/IDA) |
Positive regulation of actin-dependent ATPase activity GO:1904623
Any process that activates or increases the frequency, rate or extent of actin-dependent ATPase activity.
|
1 | Q02088 (/IDA) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q02088 (/HDA) |
Actomyosin contractile ring GO:0005826
A cytoskeletal structure composed of actin filaments and myosin that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the spindle, i.e. the cell division plane. In animal cells, the contractile ring is located at the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the contractile ring forms at the mother-bud neck before mitosis.
|
1 | Q02088 (/IDA) |
Actin filament GO:0005884
A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
|
1 | Q02088 (/IDA) |
Actin cortical patch GO:0030479
An endocytic patch that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae.
|
1 | Q02088 (/IDA) |
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
|
1 | Q02088 (/IDA) |
Mating projection tip GO:0043332
The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.
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1 | Q02088 (/IDA) |
Formin-nucleated actin cable GO:0070648
An actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. In fungal cells, myosin motors transport cargo along actin cables toward sites of polarized cell growth; actin cables may play a similar role in pollen tube growth.
|
1 | Q02088 (/IDA) |
Actin fusion focus GO:1990819
A focus at the mating projection tip where the cell wall is degraded during conjugation with cellular fusion. Actin filaments form an aster-like structure from this location.
|
1 | Q02088 (/IDA) |