CATH Superfamily 1.20.5.170

FunFam 105: AP-1-like transcription factor YAP4

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

GO Term	Annotations	Evidence
Sequence-specific DNA binding GO:0043565 Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.	3	P40917 (/HDA) Q03935 (/HDA) Q03935 (/HDA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	2	Q03935 (/IDA) Q03935 (/IDA)
RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity GO:0001010 The function of binding to a specific DNA sequence and recruiting another transcription factor to the DNA in order to modulate transcription. The recruited factor may bind DNA directly, or may be colocalized via protein-protein interactions.	2	Q03935 (/IPI) Q03935 (/IPI)
DNA-binding transcription factor activity GO:0003700 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.	1	Q5AHD5 (/ISO)
Sequence-specific DNA binding GO:0043565 Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.	1	P40917 (/IDA)
Repressing transcription factor binding GO:0070491 Interacting selectively and non-covalently with a transcription repressor, any protein whose activity is required to prevent or downregulate transcription.	1	P40917 (/IDA)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

GO Term	Annotations	Evidence
Negative regulation of transcription by RNA polymerase II GO:0000122 Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.	2	Q03935 (/IMP) Q03935 (/IMP)
Negative regulation of transcription by RNA polymerase II GO:0000122 Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.	2	Q03935 (/IPI) Q03935 (/IPI)
Positive regulation of transcription by RNA polymerase II GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	2	Q03935 (/IMP) Q03935 (/IMP)
Regulation of transcription, DNA-templated GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.	1	Q5AHD5 (/ISO)
Regulation of transcription by RNA polymerase II GO:0006357 Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.	1	P40917 (/ISA)
Hyperosmotic response GO:0006972 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.	1	P40917 (/IGI)
Response to drug GO:0042493 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.	1	P40917 (/IMP)
Hyperosmotic salinity response GO:0042538 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	1	P40917 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

GO Term	Annotations	Evidence
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	3	P40917 (/IDA) Q03935 (/IDA) Q03935 (/IDA)
Cytoplasm GO:0005737 All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	1	P40917 (/IDA)

Functional Families

There are 6 GO terms relating to "molecular function"

There are 8 GO terms relating to "biological process"

There are 2 GO terms relating to "cellular component"