The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Vesicle transport through interaction with t-SNARE...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
17 O88384 (/IPI) P58200 (/IPI) Q04338 (/IPI) Q04338 (/IPI) Q04338 (/IPI) Q04338 (/IPI) Q04338 (/IPI) Q04338 (/IPI) Q04338 (/IPI) Q04338 (/IPI)
(7 more)
SNAP receptor activity GO:0005484
Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion.
8 Q04338 (/IDA) Q04338 (/IDA) Q04338 (/IDA) Q04338 (/IDA) Q04338 (/IDA) Q04338 (/IDA) Q04338 (/IDA) Q04338 (/IDA)
SNARE binding GO:0000149
Interacting selectively and non-covalently with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.
3 Q9UEU0 (/IDA) Q9UEU0 (/IDA) Q9UEU0 (/IDA)
Chloride channel inhibitor activity GO:0019869
Stops, prevents, or reduces the activity of a chloride channel.
3 Q9UEU0 (/IDA) Q9UEU0 (/IDA) Q9UEU0 (/IDA)
Soluble NSF attachment protein activity GO:0005483
Interacting selectively and non-covalently with both N-ethylmaleimide-sensitive fusion protein (NSF) and a cis-SNARE complex (i.e. a SNARE complex in which all proteins are associated with the same membrane) and increasing the ATPase activity of NSF, thereby allowing ATP hydrolysis by NSF to disassemble the cis-SNARE complex.
2 Q9SEL5 (/TAS) Q9SEL5 (/TAS)
SNARE binding GO:0000149
Interacting selectively and non-covalently with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.
1 O88384 (/ISO)
SNAP receptor activity GO:0005484
Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion.
1 B7Z0M0 (/ISM)
SNAP receptor activity GO:0005484
Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion.
1 P78768 (/ISO)
SNAP receptor activity GO:0005484
Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion.
1 Q9W0N6 (/ISS)
Chloride channel inhibitor activity GO:0019869
Stops, prevents, or reduces the activity of a chloride channel.
1 O88384 (/ISO)
Showing 1 to 10 of 10 entries

There are 27 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Vesicle fusion GO:0006906
Fusion of the membrane of a transport vesicle with its target membrane.
9 Q04338 (/IDA) Q04338 (/IDA) Q04338 (/IDA) Q04338 (/IDA) Q04338 (/IDA) Q04338 (/IDA) Q04338 (/IDA) Q04338 (/IDA) Q54CK6 (/IDA)
Intra-Golgi vesicle-mediated transport GO:0006891
The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network).
8 Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP)
Golgi to vacuole transport GO:0006896
The directed movement of substances from the Golgi to the vacuole.
8 Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP)
Macroautophagy GO:0016236
The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.
8 Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP)
Vacuole fusion, non-autophagic GO:0042144
The fusion of two vacuole membranes to form a single vacuole.
8 Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP) Q04338 (/IMP)
Platelet degranulation GO:0002576
The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
3 Q9UEU0 (/TAS) Q9UEU0 (/TAS) Q9UEU0 (/TAS)
Protein targeting to vacuole GO:0006623
The process of directing proteins towards the vacuole, usually using signals contained within the protein.
3 Q9SEL5 (/IMP) Q9SEL5 (/IMP) Q9SEL6 (/IMP)
Vesicle docking involved in exocytosis GO:0006904
The initial attachment of a vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, that contributes to exocytosis.
3 Q9UEU0 (/TAS) Q9UEU0 (/TAS) Q9UEU0 (/TAS)
Vesicle-mediated transport GO:0016192
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
3 Q9UEU0 (/TAS) Q9UEU0 (/TAS) Q9UEU0 (/TAS)
Membrane fusion GO:0061025
The membrane organization process that joins two lipid bilayers to form a single membrane.
3 Q9UEU0 (/TAS) Q9UEU0 (/TAS) Q9UEU0 (/TAS)
Showing 1 to 10 of 27 entries

There are 59 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
9 Q2UJN0 (/IDA) Q2UJN0 (/IDA) Q2UJN0 (/IDA) Q2UJN0 (/IDA) Q2UJN0 (/IDA) Q2UJN0 (/IDA) Q2UJN0 (/IDA) Q2UJN0 (/IDA) Q9SEL6 (/IDA)
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
8 Q04338 (/HDA) Q04338 (/HDA) Q04338 (/HDA) Q04338 (/HDA) Q04338 (/HDA) Q04338 (/HDA) Q04338 (/HDA) Q04338 (/HDA)
Integral component of Golgi membrane GO:0030173
The component of the Golgi membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
8 Q04338 (/IDA) Q04338 (/IDA) Q04338 (/IDA) Q04338 (/IDA) Q04338 (/IDA) Q04338 (/IDA) Q04338 (/IDA) Q04338 (/IDA)
Cell septum GO:0030428
A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.
8 Q2UJN0 (/IDA) Q2UJN0 (/IDA) Q2UJN0 (/IDA) Q2UJN0 (/IDA) Q2UJN0 (/IDA) Q2UJN0 (/IDA) Q2UJN0 (/IDA) Q2UJN0 (/IDA)
SNARE complex GO:0031201
A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25.
8 Q04338 (/IPI) Q04338 (/IPI) Q04338 (/IPI) Q04338 (/IPI) Q04338 (/IPI) Q04338 (/IPI) Q04338 (/IPI) Q04338 (/IPI)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
6 O88384 (/IDA) Q9SEL5 (/IDA) Q9SEL5 (/IDA) Q9UEU0 (/IDA) Q9UEU0 (/IDA) Q9UEU0 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
4 O88384 (/IDA) Q9UEU0 (/IDA) Q9UEU0 (/IDA) Q9UEU0 (/IDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
3 Q9UEU0 (/TAS) Q9UEU0 (/TAS) Q9UEU0 (/TAS)
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
3 Q9UEU0 (/IDA) Q9UEU0 (/IDA) Q9UEU0 (/IDA)
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
3 O88384 (/ISS) P58200 (/ISS) Q2KIU0 (/ISS)
Showing 1 to 10 of 59 entries
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