The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
dopa decarboxylase, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 1: Histidine decarboxylase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 32 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Aromatic-L-amino-acid decarboxylase activity GO:0004058
Catalysis of the reaction: L-amino acid + H+ = R-H + CO2.
8 A8MQJ1 (/IDA) O88533 (/IDA) O88533 (/IDA) P05031 (/IDA) P05031 (/IDA) P14173 (/IDA) P20711 (/IDA) P20711 (/IDA)
L-dopa decarboxylase activity GO:0036468
Catalysis of the reaction: L-dopa + H+ = CO2 + dopamine.
5 P18486 (/IDA) P18486 (/IDA) P20711 (/IDA) P20711 (/IDA) Q16S21 (/IDA)
Histidine decarboxylase activity GO:0004398
Catalysis of the reaction: L-histidine = histamine + CO2.
4 A0A068Q816 (/IDA) F1NXM1 (/IDA) P16453 (/IDA) P19113 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 P14173 (/IPI) P19113 (/IPI) P20711 (/IPI) P20711 (/IPI)
Histidine decarboxylase activity GO:0004398
Catalysis of the reaction: L-histidine = histamine + CO2.
3 P23738 (/IMP) Q05733 (/IMP) Q05733 (/IMP)
Histidine decarboxylase activity GO:0004398
Catalysis of the reaction: L-histidine = histamine + CO2.
3 Q05733 (/ISS) Q05733 (/ISS) Q5EA83 (/ISS)
Tyrosine decarboxylase activity GO:0004837
Catalysis of the reaction: L-tyrosine = tyramine + CO2.
3 A8MQJ1 (/IDA) Q94EE9 (/IDA) Q94EE9 (/IDA)
Tyrosine decarboxylase activity GO:0004837
Catalysis of the reaction: L-tyrosine = tyramine + CO2.
3 A1Z6N2 (/ISS) A1Z6N4 (/ISS) Q8MZ32 (/ISS)
Amino acid binding GO:0016597
Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents.
3 O88533 (/ISO) O88533 (/ISO) P23738 (/ISO)
Pyridoxal phosphate binding GO:0030170
Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
3 O88533 (/ISO) O88533 (/ISO) P23738 (/ISO)
Showing 1 to 10 of 32 entries

There are 70 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
5 A8MQJ1 (/IEP) P05031 (/IEP) P05031 (/IEP) Q8RY79 (/IEP) Q8RY79 (/IEP)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
4 A7KBS5 (/IMP) F8W271 (/IMP) F8W5Y8 (/IMP) Q7SZR0 (/IMP)
Thermotaxis GO:0043052
The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature.
4 P05031 (/IMP) P05031 (/IMP) Q05733 (/IMP) Q05733 (/IMP)
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
3 A7KBS5 (/IMP) F8W271 (/IMP) F8W5Y8 (/IMP)
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
3 A7KBS5 (/IMP) F8W271 (/IMP) F8W5Y8 (/IMP)
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
3 A7KBS5 (/IMP) F8W271 (/IMP) F8W5Y8 (/IMP)
Oviposition GO:0018991
The deposition of eggs (either fertilized or not) upon a surface or into a medium such as water.
3 A1Z6N4 (/IMP) H2KYG4 (/IMP) O45137 (/IMP)
Cuticle development GO:0042335
The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss.
3 P18486 (/IDA) P18486 (/IDA) Q16S21 (/IDA)
Catecholamine biosynthetic process GO:0042423
The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.
3 P14173 (/TAS) P20711 (/TAS) P20711 (/TAS)
Catecholamine catabolic process GO:0042424
The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.
3 P18486 (/IDA) P18486 (/IDA) Q16S21 (/IDA)
Showing 1 to 10 of 70 entries

There are 15 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 A8MQJ1 (/IDA) O88533 (/IDA) O88533 (/IDA) P14173 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 P19113 (/TAS) P20711 (/TAS) P20711 (/TAS)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
3 P14173 (/IDA) P16453 (/IDA) Q95ZS2 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
3 O88533 (/ISO) O88533 (/ISO) P23738 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 O88533 (/ISO) O88533 (/ISO)
Synaptic vesicle GO:0008021
A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
2 O88533 (/ISO) O88533 (/ISO)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
2 P14173 (/IDA) Q95ZS2 (/IDA)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
2 O88533 (/ISO) O88533 (/ISO)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 P20711 (/HDA) P20711 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 O45137 (/ISS)
Showing 1 to 10 of 15 entries
CATH-Gene3D is a Global Biodata Core Resource Learn more...