CATH Superfamily 1.20.1250.10
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 2: Growth hormone
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 11 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Growth hormone receptor binding GO:0005131
Interacting selectively and non-covalently with the growth hormone receptor.
|
23 |
A4GX95 (/IMP)
A4GX95 (/IMP)
A4GX95 (/IMP)
A4GX95 (/IMP)
A4GX95 (/IMP)
A4LAP1 (/IMP)
B0FPG4 (/IMP)
B0FPG4 (/IMP)
B0FPG6 (/IMP)
B0FPG6 (/IMP)
(13 more) |
|
Cysteine-type endopeptidase activity involved in apoptotic process GO:0097153
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic process.
|
16 |
E5Q3H3 (/IDA)
H6ULW9 (/IDA)
H6ULX0 (/IDA)
H6ULX1 (/IDA)
H6ULX7 (/IDA)
H6UQ57 (/IDA)
H6UQ58 (/IDA)
H6UQ60 (/IDA)
H6UQ61 (/IDA)
H6UQ62 (/IDA)
(6 more) |
|
Cysteine-type endopeptidase activity involved in apoptotic process GO:0097153
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic process.
|
16 |
A0A087RIM6 (/ISS)
A0A093NDD2 (/ISS)
B8XY22 (/ISS)
G1N9C6 (/ISS)
G3LUM5 (/ISS)
G3LUM5 (/ISS)
P11228 (/ISS)
P11228 (/ISS)
P22077 (/ISS)
Q549W9 (/ISS)
(6 more) |
|
Growth hormone receptor binding GO:0005131
Interacting selectively and non-covalently with the growth hormone receptor.
|
6 | P01246 (/IDA) P01246 (/IDA) P01246 (/IDA) P01246 (/IDA) P01246 (/IDA) P01246 (/IDA) |
|
Growth hormone receptor binding GO:0005131
Interacting selectively and non-covalently with the growth hormone receptor.
|
2 | P06880 (/IPI) P06880 (/IPI) |
|
Growth hormone receptor binding GO:0005131
Interacting selectively and non-covalently with the growth hormone receptor.
|
2 | P06880 (/ISO) P06880 (/ISO) |
|
Hormone activity GO:0005179
The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.
|
2 | P01244 (/IDA) P01244 (/IDA) |
|
Hormone activity GO:0005179
The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.
|
2 | P06880 (/ISO) P06880 (/ISO) |
|
Glucose-6-phosphatase activity GO:0004346
Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate.
|
1 | A7UIY9 (/IMP) |
|
Growth hormone receptor binding GO:0005131
Interacting selectively and non-covalently with the growth hormone receptor.
|
1 | Q2PQK2 (/ISS) |
Showing 1 to 10 of 11 entries
There are 97 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Insulin secretion GO:0030073
The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects.
|
62 |
A0FJ27 (/ISS)
A1Z074 (/ISS)
A1Z074 (/ISS)
A1Z074 (/ISS)
A1Z074 (/ISS)
A1Z074 (/ISS)
A1Z074 (/ISS)
A4GX98 (/ISS)
A5YVX0 (/ISS)
A5YVX0 (/ISS)
(52 more) |
|
Magnesium ion homeostasis GO:0010960
Any process involved in the maintenance of an internal steady state of magnesium ions within an organism or cell.
|
40 |
A0FJ27 (/IMP)
A4GX92 (/IMP)
A4GX93 (/IMP)
A4GX94 (/IMP)
A7UIY9 (/IMP)
C8CP44 (/IMP)
G3CI04 (/IMP)
P67930 (/IMP)
P67930 (/IMP)
P67930 (/IMP)
(30 more) |
|
Positive regulation of superoxide anion generation GO:0032930
Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell.
|
40 |
A0FJ27 (/IMP)
A4GX92 (/IMP)
A4GX93 (/IMP)
A4GX94 (/IMP)
A7UIY9 (/IMP)
C8CP44 (/IMP)
G3CI04 (/IMP)
P67930 (/IMP)
P67930 (/IMP)
P67930 (/IMP)
(30 more) |
|
Hyperosmotic salinity response GO:0042538
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
|
40 |
A0FJ27 (/IMP)
A4GX92 (/IMP)
A4GX93 (/IMP)
A4GX94 (/IMP)
A7UIY9 (/IMP)
C8CP44 (/IMP)
G3CI04 (/IMP)
P67930 (/IMP)
P67930 (/IMP)
P67930 (/IMP)
(30 more) |
|
Calcium ion homeostasis GO:0055074
Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell.
|
40 |
A0FJ27 (/IMP)
A4GX92 (/IMP)
A4GX93 (/IMP)
A4GX94 (/IMP)
A7UIY9 (/IMP)
C8CP44 (/IMP)
G3CI04 (/IMP)
P67930 (/IMP)
P67930 (/IMP)
P67930 (/IMP)
(30 more) |
|
Sodium ion homeostasis GO:0055078
Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.
|
40 |
A0FJ27 (/IMP)
A4GX92 (/IMP)
A4GX93 (/IMP)
A4GX94 (/IMP)
A7UIY9 (/IMP)
C8CP44 (/IMP)
G3CI04 (/IMP)
P67930 (/IMP)
P67930 (/IMP)
P67930 (/IMP)
(30 more) |
|
Positive regulation of sodium:potassium-exchanging ATPase activity GO:1903408
Any process that activates or increases the frequency, rate or extent of sodium:potassium-exchanging ATPase activity.
|
40 |
A0FJ27 (/IMP)
A4GX92 (/IMP)
A4GX93 (/IMP)
A4GX94 (/IMP)
A7UIY9 (/IMP)
C8CP44 (/IMP)
G3CI04 (/IMP)
P67930 (/IMP)
P67930 (/IMP)
P67930 (/IMP)
(30 more) |
|
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
39 |
A4GX95 (/IDA)
A4GX95 (/IDA)
A4GX95 (/IDA)
A4GX95 (/IDA)
A4GX95 (/IDA)
A4LAP1 (/IDA)
B0FPG4 (/IDA)
B0FPG4 (/IDA)
B0FPG6 (/IDA)
B0FPG6 (/IDA)
(29 more) |
|
Response to food GO:0032094
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.
|
25 |
A4GX95 (/IDA)
A4GX95 (/IDA)
A4GX95 (/IDA)
A4GX95 (/IDA)
A4GX95 (/IDA)
A4LAP1 (/IDA)
B0FPG4 (/IDA)
B0FPG4 (/IDA)
B0FPG6 (/IDA)
B0FPG6 (/IDA)
(15 more) |
|
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
23 |
A4GX95 (/IDA)
A4GX95 (/IDA)
A4GX95 (/IDA)
A4GX95 (/IDA)
A4GX95 (/IDA)
A4LAP1 (/IDA)
B0FPG4 (/IDA)
B0FPG4 (/IDA)
B0FPG6 (/IDA)
B0FPG6 (/IDA)
(13 more) |
Showing 1 to 10 of 97 entries
There are 16 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
75 |
A0A087RIM6 (/ISS)
A0A093NDD2 (/ISS)
A0FJ27 (/ISS)
A1Z074 (/ISS)
A1Z074 (/ISS)
A1Z074 (/ISS)
A1Z074 (/ISS)
A1Z074 (/ISS)
A1Z074 (/ISS)
A4GX98 (/ISS)
(65 more) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
43 |
A4GX95 (/IDA)
A4GX95 (/IDA)
A4GX95 (/IDA)
A4GX95 (/IDA)
A4GX95 (/IDA)
A4LAP1 (/IDA)
B0FPG4 (/IDA)
B0FPG4 (/IDA)
B0FPG6 (/IDA)
B0FPG6 (/IDA)
(33 more) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
4 | P01244 (/TAS) P01244 (/TAS) P06880 (/TAS) P06880 (/TAS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | P01244 (/IDA) P01244 (/IDA) P06880 (/IDA) P06880 (/IDA) |
|
Secretory granule GO:0030141
A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
|
4 | P01244 (/IDA) P01244 (/IDA) P06880 (/IDA) P06880 (/IDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | P06880 (/ISO) P06880 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | P06880 (/ISO) P06880 (/ISO) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | P01244 (/IDA) P01244 (/IDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | P06880 (/ISO) P06880 (/ISO) |
|
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
|
2 | P06880 (/IDA) P06880 (/IDA) |
Showing 1 to 10 of 16 entries
