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CATH Superfamily 1.20.120.830

Serine-rich domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Serine-rich domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Serine-rich domain

According to literature DOI:10.1074/jbc.M501258200), p130cas (Crk-associated substrate) is a docking protein that is involved in assembly of focal adhesions and concomitant cellular signalling. The serine-rich region, a stable four-helix bundle motif, is positioned between Crk and Src-binding sites and is associated with protein-protein interactions PFAM:PF08824.

GO Diversity

Unique GO annotations
54 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
334 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 2
Domain clusters (>95% seq id): 2
Domain clusters (>35% seq id): 2
Unique PDBs: 2
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 5
Function
Unique EC:
Unique GO: 54
Taxonomy
Unique Species: 334
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