The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Axin interactor, dorsalization-associated protein, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Axin interactor, dorsalization-associated protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
22 Q8C4Q6 (/IPI) Q96BJ3 (/IPI) Q96BJ3 (/IPI) Q96BJ3 (/IPI) Q96BJ3 (/IPI) Q96BJ3 (/IPI) Q96BJ3 (/IPI) Q96BJ3 (/IPI) Q96BJ3 (/IPI) Q96BJ3 (/IPI)
(12 more)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
1 Q8C4Q6 (/IPI)
Phosphatidylinositol binding GO:0035091
Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
1 Q6PBN2 (/IDA)

There are 20 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Dorsal/ventral pattern formation GO:0009953
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
46 Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS)
(36 more)
Regulation of protein homodimerization activity GO:0043496
Any process that modulates the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.
46 Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS)
(36 more)
Negative regulation of JNK cascade GO:0046329
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade.
45 Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS) Q5RAV3 (/ISS)
(35 more)
Negative regulation of JUN kinase activity GO:0043508
Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity.
23 Q6PBN2 (/IDA) Q8C4Q6 (/IDA) Q96BJ3 (/IDA) Q96BJ3 (/IDA) Q96BJ3 (/IDA) Q96BJ3 (/IDA) Q96BJ3 (/IDA) Q96BJ3 (/IDA) Q96BJ3 (/IDA) Q96BJ3 (/IDA)
(13 more)
Negative regulation of JNK cascade GO:0046329
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade.
2 Q6PBN2 (/IMP) Q8C4Q6 (/IMP)
Dorsal/ventral pattern formation GO:0009953
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
1 Q6PBN2 (/IDA)
Dorsal/ventral pattern formation GO:0009953
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
1 Q6PBN2 (/IMP)
Dorsal/ventral pattern formation GO:0009953
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
1 Q8C4Q6 (/ISO)
Regulation of protein homodimerization activity GO:0043496
Any process that modulates the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.
1 Q8C4Q6 (/IMP)
Negative regulation of JUN kinase activity GO:0043508
Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity.
1 Q8C4Q6 (/IMP)
Negative regulation of JUN kinase activity GO:0043508
Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity.
1 Q8C4Q6 (/ISO)
Negative regulation of JNK cascade GO:0046329
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade.
1 Q6PBN2 (/IDA)
Negative regulation of JNK cascade GO:0046329
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade.
1 Q8C4Q6 (/IPI)
Negative regulation of JNK cascade GO:0046329
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade.
1 Q8C4Q6 (/ISO)
Determination of ventral identity GO:0048264
The regionalization process that results in the determination of the identity of part of an organism or organ where those parts are of the type that occur in the ventral region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
1 Q6PBN2 (/IDA)
Determination of ventral identity GO:0048264
The regionalization process that results in the determination of the identity of part of an organism or organ where those parts are of the type that occur in the ventral region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
1 Q6PBN2 (/IMP)
Determination of ventral identity GO:0048264
The regionalization process that results in the determination of the identity of part of an organism or organ where those parts are of the type that occur in the ventral region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
1 Q8C4Q6 (/ISO)
Negative regulation of determination of dorsal identity GO:2000016
Any process that stops, prevents, or reduces the frequency, rate or extent of determination of dorsal identity.
1 Q6PBN2 (/IDA)
Negative regulation of determination of dorsal identity GO:2000016
Any process that stops, prevents, or reduces the frequency, rate or extent of determination of dorsal identity.
1 Q6PBN2 (/IMP)
Negative regulation of determination of dorsal identity GO:2000016
Any process that stops, prevents, or reduces the frequency, rate or extent of determination of dorsal identity.
1 Q8C4Q6 (/ISO)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q8C4Q6 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q6PBN2 (/IDA)
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