The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Glycerol uptake facilitator protein.
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 13: Aquaporin NIP2-1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Silicate transmembrane transporter activity GO:0015115
Enables the transfer of silicates from one side of a membrane to the other. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si
6 Q6Z2T3 (/IDA) Q6Z2T3 (/IDA) Q6Z2T3 (/IDA) Q6Z2T3 (/IDA) Q6Z2T3 (/IDA) Q6Z2T3 (/IDA)
Active borate transmembrane transporter activity GO:0046715
Enables the transport of borate across a membrane against the concentration gradient.
5 Q8LAI1 (/IDA) Q8LAI1 (/IDA) Q9SAI4 (/IDA) Q9SV84 (/IDA) Q9SV84 (/IDA)
Arsenite transmembrane transporter activity GO:0015105
Enables the transfer of arsenite from one side of a membrane to the other.
2 Q9SV84 (/IDA) Q9SV84 (/IDA)
Water channel activity GO:0015250
Transport systems of this type enable facilitated diffusion of water (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2 Q9SV84 (/IDA) Q9SV84 (/IDA)
Glycerol transmembrane transporter activity GO:0015168
Enables the transfer of glycerol from one side of a membrane to the other. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
1 Q9SAI4 (/IDA)
Urea transmembrane transporter activity GO:0015204
Enables the transfer of urea from one side of a membrane to the other. Urea is the water soluble compound H2N-CO-NH2.
1 Q9SAI4 (/IDA)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Silicic acid import across plasma membrane GO:0015708
The directed movement of silicates from outside of a cell, across the plasma membrane and into the cytosol. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si
6 Q6Z2T3 (/IMP) Q6Z2T3 (/IMP) Q6Z2T3 (/IMP) Q6Z2T3 (/IMP) Q6Z2T3 (/IMP) Q6Z2T3 (/IMP)
Urea transport GO:0015840
The directed movement of urea into, out of or within the cell. Urea is the water-soluble compound H2N-CO-NH2.
3 Q19KC1 (/IDA) Q19KC1 (/IDA) Q19KC1 (/IDA)
Cellular response to boron-containing substance levels GO:0080029
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of boron-containing substances.
3 Q9SAI4 (/IEP) Q9SV84 (/IEP) Q9SV84 (/IEP)
Response to boron-containing substance GO:0010036
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a boron-containing substance stimulus.
2 Q9SV84 (/IEP) Q9SV84 (/IEP)
Response to boron-containing substance GO:0010036
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a boron-containing substance stimulus.
2 Q9SV84 (/IMP) Q9SV84 (/IMP)
Arsenite transport GO:0015700
The directed movement of arsenite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q9SV84 (/IDA) Q9SV84 (/IDA)
Borate transmembrane transport GO:0035445
The process in which borate is transported across a membrane. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals.
2 Q8LAI1 (/IDA) Q8LAI1 (/IDA)
Response to arsenic-containing substance GO:0046685
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.
2 Q9SV84 (/IMP) Q9SV84 (/IMP)
Borate transport GO:0046713
The directed movement of borate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals.
2 Q9SV84 (/IDA) Q9SV84 (/IDA)
Borate transport GO:0046713
The directed movement of borate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals.
1 Q9SAI4 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
6 Q6Z2T3 (/IDA) Q6Z2T3 (/IDA) Q6Z2T3 (/IDA) Q6Z2T3 (/IDA) Q6Z2T3 (/IDA) Q6Z2T3 (/IDA)
Casparian strip GO:0048226
Region of plant cell wall specialised to act as a seal to prevent back leakage of secreted material (analogous to tight junction between epithelial cells). Found particularly where root parenchymal cells secrete solutes into xylem vessels. The barrier is composed of suberin; a fatty substance, containing long chain fatty acids and fatty esters, also found in the cell walls of cork cells (phellem) in higher plants.
6 Q6Z2T3 (/IDA) Q6Z2T3 (/IDA) Q6Z2T3 (/IDA) Q6Z2T3 (/IDA) Q6Z2T3 (/IDA) Q6Z2T3 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 Q9SAI4 (/IDA) Q9SV84 (/IDA) Q9SV84 (/IDA)
Lateral plasma membrane GO:0016328
The portion of the plasma membrane at the lateral side of the cell. In epithelial cells, lateral plasma membranes are on the sides of cells which lie at the interface of adjacent cells.
2 Q9SV84 (/IDA) Q9SV84 (/IDA)
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