The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Glycerol uptake facilitator protein.
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Probable aquaporin PIP1-2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
21 P30302 (/IPI) P93004 (/IPI) P93004 (/IPI) P93004 (/IPI) Q08733 (/IPI) Q08733 (/IPI) Q39196 (/IPI) Q39196 (/IPI) Q41870 (/IPI) Q84RL7 (/IPI)
(11 more)
Water channel activity GO:0015250
Transport systems of this type enable facilitated diffusion of water (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
16 Q84RL7 (/TAS) Q84RL7 (/TAS) Q84RL7 (/TAS) Q9ATM4 (/TAS) Q9ATM4 (/TAS) Q9ATM4 (/TAS) Q9ATM5 (/TAS) Q9ATM5 (/TAS) Q9ATM6 (/TAS) Q9ATM6 (/TAS)
(6 more)
Water channel activity GO:0015250
Transport systems of this type enable facilitated diffusion of water (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
12 P30302 (/IDA) P43286 (/IDA) P43286 (/IDA) P43287 (/IDA) P61837 (/IDA) P61837 (/IDA) P61837 (/IDA) P93004 (/IDA) P93004 (/IDA) P93004 (/IDA)
(2 more)
Water channel activity GO:0015250
Transport systems of this type enable facilitated diffusion of water (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
11 Q39196 (/ISS) Q39196 (/ISS) Q8LAA6 (/ISS) Q8LAA6 (/ISS) Q9FF53 (/ISS) Q9FF53 (/ISS) Q9SV31 (/ISS) Q9ZV07 (/ISS) Q9ZV07 (/ISS) Q9ZVX8 (/ISS)
(1 more)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
6 P43286 (/IDA) P43286 (/IDA) P43287 (/IDA) P93004 (/IDA) P93004 (/IDA) P93004 (/IDA)
Water transmembrane transporter activity GO:0005372
Enables the transfer of water (H2O) from one side of a membrane to the other.
5 A0T2N6 (/IDA) A0T2N6 (/IDA) A0T2N6 (/IDA) A0T2N7 (/IDA) A0T2N8 (/IDA)
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
2 P43286 (/IPI) P43286 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q41372 (/IPI)

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Water transport GO:0006833
The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
13 A0T2N6 (/IDA) A0T2N6 (/IDA) A0T2N6 (/IDA) A0T2N7 (/IDA) A0T2N8 (/IDA) P43286 (/IDA) P43286 (/IDA) P43287 (/IDA) P61837 (/IDA) P61837 (/IDA)
(3 more)
Response to water deprivation GO:0009414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
11 P30302 (/IEP) P43286 (/IEP) P43286 (/IEP) P43287 (/IEP) P61837 (/IEP) P61837 (/IEP) P61837 (/IEP) Q08733 (/IEP) Q08733 (/IEP) Q39196 (/IEP)
(1 more)
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
10 P43286 (/IDA) P43286 (/IDA) P43287 (/IDA) P93004 (/IDA) P93004 (/IDA) P93004 (/IDA) Q9FF53 (/IDA) Q9FF53 (/IDA) Q9ZVX8 (/IDA) Q9ZVX8 (/IDA)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
8 Q41870 (/TAS) Q84RL7 (/TAS) Q84RL7 (/TAS) Q84RL7 (/TAS) Q9ATN0 (/TAS) Q9XF58 (/TAS) Q9XF58 (/TAS) Q9XF59 (/TAS)
Protein heterotetramerization GO:0051290
The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.
8 Q41870 (/TAS) Q84RL7 (/TAS) Q84RL7 (/TAS) Q84RL7 (/TAS) Q9ATN0 (/TAS) Q9XF58 (/TAS) Q9XF58 (/TAS) Q9XF59 (/TAS)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
5 A0T2N6 (/IEP) A0T2N6 (/IEP) A0T2N6 (/IEP) A0T2N7 (/IEP) A0T2N8 (/IEP)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
5 A0T2N6 (/IEP) A0T2N6 (/IEP) A0T2N6 (/IEP) A0T2N7 (/IEP) A0T2N8 (/IEP)
Root development GO:0048364
The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.
5 A0T2N6 (/IEP) A0T2N6 (/IEP) A0T2N6 (/IEP) A0T2N7 (/IEP) A0T2N8 (/IEP)
Hydrogen peroxide transmembrane transport GO:0080170
The process in which hydrogen peroxide is transported across a membrane.
4 P43286 (/IDA) P43286 (/IDA) Q9FF53 (/IDA) Q9FF53 (/IDA)
Water transport GO:0006833
The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3 Q39196 (/IMP) Q39196 (/IMP) Q9SV31 (/IMP)
Plant ovule development GO:0048481
The process whose specific outcome is the progression of the ovule over time, from its formation to the mature structure. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed.
3 Q06Z30 (/TAS) Q06Z30 (/TAS) Q06Z30 (/TAS)
Seed trichome elongation GO:0090378
The process in which a seed trichome irreversibly increases in size in one
3 B1NHU0 (/IEP) B1NHU0 (/IEP) B1NHU0 (/IEP)
Response to nematode GO:0009624
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a nematode.
2 Q9ZV07 (/IEP) Q9ZV07 (/IEP)
Root hair elongation GO:0048767
The process in which the root hair grows longer.
2 Q9FF53 (/IMP) Q9FF53 (/IMP)

There are 16 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
28 P30302 (/IDA) P43286 (/IDA) P43286 (/IDA) P43287 (/IDA) P61837 (/IDA) P61837 (/IDA) P61837 (/IDA) P93004 (/IDA) P93004 (/IDA) P93004 (/IDA)
(18 more)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
24 Q41870 (/TAS) Q84RL7 (/TAS) Q84RL7 (/TAS) Q84RL7 (/TAS) Q9AQU5 (/TAS) Q9AQU5 (/TAS) Q9AQU5 (/TAS) Q9AR14 (/TAS) Q9AR14 (/TAS) Q9AR14 (/TAS)
(14 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
16 P43286 (/IDA) P43286 (/IDA) P61837 (/IDA) P61837 (/IDA) P61837 (/IDA) P93004 (/IDA) P93004 (/IDA) P93004 (/IDA) Q08733 (/IDA) Q08733 (/IDA)
(6 more)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
13 P43286 (/IDA) P43286 (/IDA) P43287 (/IDA) P61837 (/IDA) P61837 (/IDA) P61837 (/IDA) P93004 (/IDA) P93004 (/IDA) P93004 (/IDA) Q8LAA6 (/IDA)
(3 more)
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
8 P43286 (/IDA) P43286 (/IDA) P61837 (/IDA) P61837 (/IDA) P61837 (/IDA) P93004 (/IDA) P93004 (/IDA) P93004 (/IDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
7 Q41870 (/TAS) Q84RL7 (/TAS) Q84RL7 (/TAS) Q84RL7 (/TAS) Q9ATN0 (/TAS) Q9XF58 (/TAS) Q9XF58 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
6 Q41870 (/IDA) Q9AQU5 (/IDA) Q9AQU5 (/IDA) Q9AQU5 (/IDA) Q9ATN0 (/IDA) Q9XF59 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5 A0T2N6 (/NAS) A0T2N6 (/NAS) A0T2N6 (/NAS) A0T2N7 (/NAS) A0T2N8 (/NAS)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
5 P43286 (/IDA) P43286 (/IDA) P43287 (/IDA) Q08733 (/IDA) Q08733 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 P93004 (/IDA) P93004 (/IDA) P93004 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 P61837 (/IDA) P61837 (/IDA) P61837 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 P93004 (/TAS) P93004 (/TAS) P93004 (/TAS)
Chloroplast envelope GO:0009941
The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
3 P61837 (/IDA) P61837 (/IDA) P61837 (/IDA)
Anchored component of plasma membrane GO:0046658
The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
3 P93004 (/IDA) P93004 (/IDA) P93004 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 Q9XF59 (/IDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q9XF59 (/IPI)
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