The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Villin headpiece domain
".
FunFam 2: Dematin isoform X2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 13 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
|
7 | Q08DM1 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q9WV69 (/ISS) |
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
7 | Q08DM1 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q9WV69 (/ISS) |
Spectrin binding GO:0030507
Interacting selectively and non-covalently with spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers.
|
7 | Q08DM1 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q9WV69 (/ISS) |
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
|
7 | Q08DM1 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q9WV69 (/ISS) |
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
|
5 | Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) |
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
5 | Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
5 | Q08495 (/IPI) Q08495 (/IPI) Q08495 (/IPI) Q08495 (/IPI) Q08495 (/IPI) |
Spectrin binding GO:0030507
Interacting selectively and non-covalently with spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers.
|
5 | Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) |
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
|
1 | Q9WV69 (/ISO) |
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
1 | Q9WV69 (/ISO) |
Spectrin binding GO:0030507
Interacting selectively and non-covalently with spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers.
|
1 | Q9WV69 (/ISO) |
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
|
1 | Q9WV69 (/IDA) |
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
|
1 | Q9WV69 (/ISO) |
There are 64 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Positive regulation of fibroblast migration GO:0010763
Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Negative regulation of peptidyl-threonine phosphorylation GO:0010801
Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Negative regulation of cell-substrate adhesion GO:0010812
Any process that decreases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Positive regulation of blood coagulation GO:0030194
Any process that activates or increases the frequency, rate or extent of blood coagulation.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Negative regulation of peptidyl-serine phosphorylation GO:0033137
Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-serine.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Calcium-mediated signaling using intracellular calcium source GO:0035584
A series of molecular signals in which a cell uses calcium ions released from an intracellular store to convert a signal into a response.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Calcium-mediated signaling using extracellular calcium source GO:0035585
A series of molecular signals in which a cell uses calcium ions imported from an extracellular source to convert a signal into a response.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Erythrocyte development GO:0048821
The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Negative regulation of peptidyl-tyrosine phosphorylation GO:0050732
Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Negative regulation of focal adhesion assembly GO:0051895
Any process that stops, prevents, or reduces the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Protein secretion by platelet GO:0070560
The regulated release of proteins by a platelet or group of platelets.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Positive regulation of wound healing GO:0090303
Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Negative regulation of protein targeting to membrane GO:0090315
Any process that decreases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Actin filament reorganization GO:0090527
A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of actin filaments.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Negative regulation of substrate adhesion-dependent cell spreading GO:1900025
Any process that stops, prevents or reduces the frequency, rate or extent of substrate adhesion-dependent cell spreading.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Positive regulation of substrate adhesion-dependent cell spreading GO:1900026
Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Positive regulation of platelet aggregation GO:1901731
Any process that activates or increases the frequency, rate or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Positive regulation of integrin-mediated signaling pathway GO:2001046
Any process that activates or increases the frequency, rate or extent of integrin-mediated signaling pathway.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
|
7 | Q08DM1 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q9WV69 (/ISS) |
Regulation of lamellipodium assembly GO:0010591
Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
|
7 | Q08DM1 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q9WV69 (/ISS) |
Regulation of actin cytoskeleton organization GO:0032956
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
|
7 | Q08DM1 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q9WV69 (/ISS) |
Actin filament bundle assembly GO:0051017
The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
|
7 | Q08DM1 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q9WV69 (/ISS) |
Regulation of filopodium assembly GO:0051489
Any process that modulates the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
|
7 | Q08DM1 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q9WV69 (/ISS) |
Cellular response to cAMP GO:0071320
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
|
7 | Q08DM1 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q9WV69 (/ISS) |
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
|
6 | Q08495 (/IMP) Q08495 (/IMP) Q08495 (/IMP) Q08495 (/IMP) Q08495 (/IMP) Q9WV69 (/IMP) |
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
|
6 | Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q9WV69 (/IDA) |
Cytoskeleton organization GO:0007010
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
|
5 | Q08495 (/TAS) Q08495 (/TAS) Q08495 (/TAS) Q08495 (/TAS) Q08495 (/TAS) |
Regulation of lamellipodium assembly GO:0010591
Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
|
5 | Q08495 (/IMP) Q08495 (/IMP) Q08495 (/IMP) Q08495 (/IMP) Q08495 (/IMP) |
Regulation of actin cytoskeleton organization GO:0032956
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
|
5 | Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) |
Actin filament bundle assembly GO:0051017
The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
|
5 | Q08495 (/TAS) Q08495 (/TAS) Q08495 (/TAS) Q08495 (/TAS) Q08495 (/TAS) |
Regulation of filopodium assembly GO:0051489
Any process that modulates the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
|
5 | Q08495 (/IMP) Q08495 (/IMP) Q08495 (/IMP) Q08495 (/IMP) Q08495 (/IMP) |
Transmembrane transport GO:0055085
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
|
5 | Q08495 (/TAS) Q08495 (/TAS) Q08495 (/TAS) Q08495 (/TAS) Q08495 (/TAS) |
Cellular response to cAMP GO:0071320
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
|
5 | Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) |
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
|
1 | Q9WV69 (/IDA) |
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
|
1 | Q9WV69 (/ISO) |
Regulation of lamellipodium assembly GO:0010591
Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
|
1 | Q9WV69 (/ISO) |
Positive regulation of fibroblast migration GO:0010763
Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.
|
1 | Q9WV69 (/IDA) |
Negative regulation of peptidyl-threonine phosphorylation GO:0010801
Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
|
1 | Q9WV69 (/IMP) |
Negative regulation of cell-substrate adhesion GO:0010812
Any process that decreases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.
|
1 | Q9WV69 (/IMP) |
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
|
1 | Q9WV69 (/IMP) |
Positive regulation of blood coagulation GO:0030194
Any process that activates or increases the frequency, rate or extent of blood coagulation.
|
1 | Q9WV69 (/IMP) |
Regulation of actin cytoskeleton organization GO:0032956
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
|
1 | Q9WV69 (/ISO) |
Negative regulation of peptidyl-serine phosphorylation GO:0033137
Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-serine.
|
1 | Q9WV69 (/IMP) |
Calcium-mediated signaling using intracellular calcium source GO:0035584
A series of molecular signals in which a cell uses calcium ions released from an intracellular store to convert a signal into a response.
|
1 | Q9WV69 (/IMP) |
Calcium-mediated signaling using extracellular calcium source GO:0035585
A series of molecular signals in which a cell uses calcium ions imported from an extracellular source to convert a signal into a response.
|
1 | Q9WV69 (/IMP) |
Erythrocyte development GO:0048821
The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure.
|
1 | Q9WV69 (/IMP) |
Negative regulation of peptidyl-tyrosine phosphorylation GO:0050732
Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
|
1 | Q9WV69 (/IMP) |
Actin filament bundle assembly GO:0051017
The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
|
1 | Q9WV69 (/ISO) |
Regulation of filopodium assembly GO:0051489
Any process that modulates the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
|
1 | Q9WV69 (/ISO) |
Negative regulation of focal adhesion assembly GO:0051895
Any process that stops, prevents, or reduces the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.
|
1 | Q9WV69 (/IMP) |
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
|
1 | Q9WV69 (/ISO) |
Protein secretion by platelet GO:0070560
The regulated release of proteins by a platelet or group of platelets.
|
1 | Q9WV69 (/IMP) |
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
1 | Q9WV69 (/IMP) |
Cellular response to cAMP GO:0071320
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
|
1 | Q9WV69 (/ISO) |
Positive regulation of wound healing GO:0090303
Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
|
1 | Q9WV69 (/IMP) |
Negative regulation of protein targeting to membrane GO:0090315
Any process that decreases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
|
1 | Q9WV69 (/IMP) |
Actin filament reorganization GO:0090527
A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of actin filaments.
|
1 | Q9WV69 (/IMP) |
Negative regulation of substrate adhesion-dependent cell spreading GO:1900025
Any process that stops, prevents or reduces the frequency, rate or extent of substrate adhesion-dependent cell spreading.
|
1 | Q9WV69 (/IMP) |
Positive regulation of substrate adhesion-dependent cell spreading GO:1900026
Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.
|
1 | Q9WV69 (/IMP) |
Positive regulation of platelet aggregation GO:1901731
Any process that activates or increases the frequency, rate or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
|
1 | Q9WV69 (/IMP) |
Positive regulation of integrin-mediated signaling pathway GO:2001046
Any process that activates or increases the frequency, rate or extent of integrin-mediated signaling pathway.
|
1 | Q9WV69 (/IMP) |
There are 27 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cell projection membrane GO:0031253
The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
11 |
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08495 (/ISS)
Q08DM1 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
Q5R4B6 (/ISS)
(1 more) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
7 | Q08DM1 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q9WV69 (/ISS) |
Actin filament GO:0005884
A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
|
7 | Q08DM1 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q9WV69 (/ISS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
7 | Q08DM1 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q9WV69 (/ISS) |
Spectrin-associated cytoskeleton GO:0014731
The part of the cytoskeleton composed of spectrin, protein 4.1 and ankyrin. Spectrin-associated cytoskeleton is associated with the plasma membrane.
|
7 | Q08DM1 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q9WV69 (/ISS) |
Platelet dense tubular network membrane GO:0031095
The lipid bilayer surrounding the platelet dense tubular network.
|
7 | Q08DM1 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q9WV69 (/ISS) |
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
|
7 | Q08DM1 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q5R4B6 (/ISS) Q9WV69 (/ISS) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
6 | Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q9WV69 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | Q08495 (/TAS) Q08495 (/TAS) Q08495 (/TAS) Q08495 (/TAS) Q08495 (/TAS) |
Actin filament GO:0005884
A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
|
5 | Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
5 | Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) |
Spectrin-associated cytoskeleton GO:0014731
The part of the cytoskeleton composed of spectrin, protein 4.1 and ankyrin. Spectrin-associated cytoskeleton is associated with the plasma membrane.
|
5 | Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) |
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
|
5 | Q08495 (/TAS) Q08495 (/TAS) Q08495 (/TAS) Q08495 (/TAS) Q08495 (/TAS) |
Platelet dense tubular network membrane GO:0031095
The lipid bilayer surrounding the platelet dense tubular network.
|
5 | Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) |
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
|
5 | Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) Q08495 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9WV69 (/ISO) |
Actin filament GO:0005884
A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
|
1 | Q9WV69 (/ISO) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9WV69 (/ISO) |
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
|
1 | Q9WV69 (/IDA) |
Spectrin-associated cytoskeleton GO:0014731
The part of the cytoskeleton composed of spectrin, protein 4.1 and ankyrin. Spectrin-associated cytoskeleton is associated with the plasma membrane.
|
1 | Q9WV69 (/ISO) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q9WV69 (/IDA) |
Cortical cytoskeleton GO:0030863
The portion of the cytoskeleton that lies just beneath the plasma membrane.
|
1 | Q9WV69 (/IDA) |
Platelet dense tubular network membrane GO:0031095
The lipid bilayer surrounding the platelet dense tubular network.
|
1 | Q9WV69 (/ISO) |
Cell projection membrane GO:0031253
The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection.
|
1 | Q9WV69 (/IDA) |
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
|
1 | Q9WV69 (/ISO) |
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q9WV69 (/IDA) |