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CATH Superfamily 1.10.8.700

Bacteriophage clamp loader A subunit, A domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Bacteriophage clamp loader A subunit, A domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Bacteriophage clamp loader A subunit, A domain

Structural domains comprising this superfamily share the structure of the A' domain of subunit A of the pentameric bacteriophage DNA clamp loader, involved in the loading of sliding clamps onto chromosomal DNA. These clamps are involved in processivity of DNA replication.

Pentameric clamp loader complexes belonging to the AAA+ family of ATPases. The A subunit is comprised of two domains termed A and A', both are involved in bridging the gap in the clamp between the A and E subunits, with the A domain (a vestigial AAA+ module) on the lower part of the clamp and the A' domain at the top. Thus, they enable the interaction with the ATPase site of the E subunit. PMID:22194570.

GO Diversity

Unique GO annotations
1 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
176 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 4
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 3
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 1
Function
Unique EC:
Unique GO: 1
Taxonomy
Unique Species: 176
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