The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Retinoid X Receptor
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 14: Oxysterols receptor LXR-alpha isoform 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 42 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
13 F1D8P7 (/IPI) F1D8P7 (/IPI) F1D8P7 (/IPI) F1D8P7 (/IPI) P55055 (/IPI) Q13133 (/IPI) Q13133 (/IPI) Q13133 (/IPI) Q13133 (/IPI) Q60644 (/IPI)
(3 more)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
5 P55055 (/ISA) Q13133 (/ISA) Q13133 (/ISA) Q13133 (/ISA) Q13133 (/ISA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
5 P55055 (/ISM) Q13133 (/ISM) Q13133 (/ISM) Q13133 (/ISM) Q13133 (/ISM)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
5 P55055 (/NAS) Q13133 (/NAS) Q13133 (/NAS) Q13133 (/NAS) Q13133 (/NAS)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
5 P55055 (/TAS) Q13133 (/TAS) Q13133 (/TAS) Q13133 (/TAS) Q13133 (/TAS)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
5 A0A0R4IVP0 (/IDA) Q56A56 (/IDA) Q60644 (/IDA) Q9Z0Y9 (/IDA) Q9Z0Y9 (/IDA)
Nuclear receptor activity GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
5 A0A0R4IVP0 (/IDA) Q56A56 (/IDA) Q60644 (/IDA) Q9Z0Y9 (/IDA) Q9Z0Y9 (/IDA)
Nuclear receptor activity GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
5 P55055 (/TAS) Q13133 (/TAS) Q13133 (/TAS) Q13133 (/TAS) Q13133 (/TAS)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
4 P55055 (/IDA) Q62755 (/IDA) Q9Z0Y9 (/IDA) Q9Z0Y9 (/IDA)
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
4 Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA)
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
4 Q5E9B6 (/ISS) Q62685 (/ISS) Q9Z0Y9 (/ISS) Q9Z0Y9 (/ISS)
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
4 Q13133 (/TAS) Q13133 (/TAS) Q13133 (/TAS) Q13133 (/TAS)
Cholesterol binding GO:0015485
Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
4 Q13133 (/TAS) Q13133 (/TAS) Q13133 (/TAS) Q13133 (/TAS)
Sterol response element binding GO:0032810
Interacting selectively and non-covalently with the sterol response element (SRE), a nonpalindromic sequence found in the promoters of genes involved in lipid metabolism.
4 Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
4 Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
3 P55055 (/IDA) Q9Z0Y9 (/IDA) Q9Z0Y9 (/IDA)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
3 Q60644 (/IDA) Q9Z0Y9 (/IDA) Q9Z0Y9 (/IDA)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
3 Q62685 (/IDA) Q8JHU1 (/IDA) Q8JHU1 (/IDA)
Retinoid X receptor binding GO:0046965
Interacting selectively and non-covalently with a retinoid X receptor.
3 Q60644 (/ISO) Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
2 Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Sterol response element binding GO:0032810
Interacting selectively and non-covalently with the sterol response element (SRE), a nonpalindromic sequence found in the promoters of genes involved in lipid metabolism.
2 Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Enhancer binding GO:0035326
Interacting selectively and non-covalently with an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
2 Q8JHU1 (/IDA) Q8JHU1 (/IDA)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
2 Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
2 Q4TU03 (/ISS) Q5E9B6 (/ISS)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
2 Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Retinoid X receptor binding GO:0046965
Interacting selectively and non-covalently with a retinoid X receptor.
2 Q60644 (/IDA) Q62755 (/IDA)
Retinoid X receptor binding GO:0046965
Interacting selectively and non-covalently with a retinoid X receptor.
2 Q62685 (/IPI) Q62755 (/IPI)
Retinoid X receptor binding GO:0046965
Interacting selectively and non-covalently with a retinoid X receptor.
2 Q4TU03 (/ISS) Q5E9B6 (/ISS)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
2 Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
1 Q62755 (/IMP)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
1 Q60644 (/ISO)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 Q62755 (/IDA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 Q60644 (/ISO)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 Q62755 (/IMP)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 Q60644 (/ISO)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
1 Q60644 (/IGI)
Steroid hormone receptor activity GO:0003707
Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.
1 Q62685 (/TAS)
Apolipoprotein A-I receptor binding GO:0034191
Interacting selectively and non-covalently with an apolipoprotein A-I receptor.
1 P55055 (/IPI)
Apolipoprotein A-I receptor binding GO:0034191
Interacting selectively and non-covalently with an apolipoprotein A-I receptor.
1 Q60644 (/ISO)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
1 Q62685 (/IDA)
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
1 P55055 (/IPI)
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
1 Q60644 (/ISO)

There are 98 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
11 P55055 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q60644 (/IDA) Q62755 (/IDA) Q8JHU1 (/IDA) Q8JHU1 (/IDA) Q9Z0Y9 (/IDA)
(1 more)
Cholesterol homeostasis GO:0042632
Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.
9 P55055 (/ISS) Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS) Q5BIS6 (/ISS) Q5E9B6 (/ISS) Q62685 (/ISS) Q62755 (/ISS)
Negative regulation of cold-induced thermogenesis GO:0120163
Any process that stops, prevents, or reduces the rate of cold-induced thermogenesis.
8 P55055 (/ISS) Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS) Q5I035 (/ISS) Q62685 (/ISS) Q62755 (/ISS)
Positive regulation of cholesterol efflux GO:0010875
Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
7 Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q60644 (/IDA) Q9Z0Y9 (/IDA) Q9Z0Y9 (/IDA)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
6 Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP) Q9Z0Y9 (/IMP) Q9Z0Y9 (/IMP)
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
6 Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q9Z0Y9 (/IDA) Q9Z0Y9 (/IDA)
Transcription initiation from RNA polymerase II promoter GO:0006367
Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
5 P55055 (/TAS) Q13133 (/TAS) Q13133 (/TAS) Q13133 (/TAS) Q13133 (/TAS)
Negative regulation of macrophage derived foam cell differentiation GO:0010745
Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
5 P55055 (/IC) Q13133 (/IC) Q13133 (/IC) Q13133 (/IC) Q13133 (/IC)
Positive regulation of triglyceride biosynthetic process GO:0010867
Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.
5 P55055 (/IMP) Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP)
Positive regulation of cholesterol efflux GO:0010875
Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
5 P55055 (/IMP) Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP)
Negative regulation of cholesterol storage GO:0010887
Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
5 P55055 (/IMP) Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP)
Positive regulation of cellular protein metabolic process GO:0032270
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
5 P55055 (/IMP) Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP)
Negative regulation of lipid transport GO:0032369
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
5 P55055 (/IMP) Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP)
Positive regulation of cholesterol transport GO:0032376
Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
5 P55055 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA)
Cholesterol homeostasis GO:0042632
Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.
5 Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q60644 (/IDA)
Positive regulation of fatty acid biosynthetic process GO:0045723
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
5 P55055 (/IMP) Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
5 P55055 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
5 P55055 (/IMP) Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP)
Negative regulation of pinocytosis GO:0048550
Any process that stops, prevents, or reduces the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.
5 P55055 (/IMP) Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP)
Positive regulation of lipoprotein lipase activity GO:0051006
Any process that activates or increases the activity of the enzyme lipoprotein lipase.
5 P55055 (/IMP) Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP)
Negative regulation of interferon-gamma-mediated signaling pathway GO:0060336
Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor.
5 P55055 (/NAS) Q13133 (/NAS) Q13133 (/NAS) Q13133 (/NAS) Q13133 (/NAS)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
4 Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS)
Positive regulation of receptor biosynthetic process GO:0010870
Any process that increases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
4 Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA)
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
4 Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA)
Positive regulation of toll-like receptor 4 signaling pathway GO:0034145
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
4 Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA)
Regulation of circadian rhythm GO:0042752
Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.
4 Q13133 (/TAS) Q13133 (/TAS) Q13133 (/TAS) Q13133 (/TAS)
Negative regulation of macrophage activation GO:0043031
Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation.
4 Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS)
Apoptotic cell clearance GO:0043277
The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte.
4 Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP) Q13133 (/IMP)
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
4 Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS)
Lipid homeostasis GO:0055088
Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.
4 Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS)
Sterol homeostasis GO:0055092
Any process involved in the maintenance of an internal steady state of sterol within an organism or cell.
4 Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS)
Triglyceride homeostasis GO:0070328
Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell.
4 Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS)
Negative regulation of pancreatic juice secretion GO:0090188
Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.
4 Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS)
Negative regulation of secretion of lysosomal enzymes GO:0090341
Any process that decreases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.
4 Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS)
Regulation of nuclear receptor transcription coactivator activity GO:2000325
Any process that modulates the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity.
4 Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA)
Regulation of nuclear receptor transcription coactivator activity GO:2000325
Any process that modulates the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity.
4 Q5E9B6 (/ISS) Q62685 (/ISS) Q9Z0Y9 (/ISS) Q9Z0Y9 (/ISS)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
3 Q60644 (/IDA) Q9Z0Y9 (/IDA) Q9Z0Y9 (/IDA)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
3 A0A060VSG9 (/IMP) A0A060WYW4 (/IMP) B8Y3M1 (/IMP)
Positive regulation of triglyceride biosynthetic process GO:0010867
Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.
3 Q60644 (/ISO) Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Positive regulation of cholesterol efflux GO:0010875
Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
3 Q60644 (/ISO) Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Negative regulation of cholesterol storage GO:0010887
Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
3 Q60644 (/ISO) Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Lipid catabolic process GO:0016042
The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
3 A0A060VSG9 (/IMP) A0A060WYW4 (/IMP) B8Y3M1 (/IMP)
Positive regulation of cellular protein metabolic process GO:0032270
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
3 Q60644 (/ISO) Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Negative regulation of lipid transport GO:0032369
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3 Q60644 (/ISO) Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Positive regulation of cholesterol transport GO:0032376
Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3 Q60644 (/ISO) Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Cholesterol homeostasis GO:0042632
Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.
3 Q60644 (/IMP) Q9Z0Y9 (/IMP) Q9Z0Y9 (/IMP)
Cellular lipid metabolic process GO:0044255
The chemical reactions and pathways involving lipids, as carried out by individual cells.
3 Q60644 (/IDA) Q9Z0Y9 (/IDA) Q9Z0Y9 (/IDA)
Positive regulation of fatty acid biosynthetic process GO:0045723
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
3 Q60644 (/ISO) Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Negative regulation of proteolysis GO:0045861
Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
3 Q60644 (/IMP) Q9Z0Y9 (/IMP) Q9Z0Y9 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
3 Q60644 (/ISO) Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
3 Q5BIS6 (/ISS) Q5E9B6 (/ISS) Q62685 (/ISS)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
3 Q60644 (/ISO) Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Negative regulation of pinocytosis GO:0048550
Any process that stops, prevents, or reduces the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.
3 Q60644 (/ISO) Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Positive regulation of lipoprotein lipase activity GO:0051006
Any process that activates or increases the activity of the enzyme lipoprotein lipase.
3 Q60644 (/ISO) Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Lipid homeostasis GO:0055088
Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.
3 Q60644 (/IMP) Q9Z0Y9 (/IMP) Q9Z0Y9 (/IMP)
Negative regulation of cold-induced thermogenesis GO:0120163
Any process that stops, prevents, or reduces the rate of cold-induced thermogenesis.
3 Q60644 (/IGI) Q9Z0Y9 (/IGI) Q9Z0Y9 (/IGI)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 Q9Z0Y9 (/IDA) Q9Z0Y9 (/IDA)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 A0A0R4IVP0 (/IDA) Q56A56 (/IDA)
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
2 Q9Z0Y9 (/TAS) Q9Z0Y9 (/TAS)
Positive regulation of receptor biosynthetic process GO:0010870
Any process that increases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
2 Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Positive regulation of cholesterol efflux GO:0010875
Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
2 Q5E9B6 (/ISS) Q62685 (/ISS)
Negative regulation of cholesterol storage GO:0010887
Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
2 Q9Z0Y9 (/IGI) Q9Z0Y9 (/IGI)
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
2 Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Positive regulation of toll-like receptor 4 signaling pathway GO:0034145
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
2 Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Cholesterol homeostasis GO:0042632
Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.
2 Q9Z0Y9 (/IGI) Q9Z0Y9 (/IGI)
Cholesterol homeostasis GO:0042632
Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.
2 Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Camera-type eye development GO:0043010
The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.
2 A0A0R4IVP0 (/IMP) Q56A56 (/IMP)
Negative regulation of macrophage activation GO:0043031
Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation.
2 Q9Z0Y9 (/IDA) Q9Z0Y9 (/IDA)
Apoptotic cell clearance GO:0043277
The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte.
2 Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 Q9Z0Y9 (/IMP) Q9Z0Y9 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 Q5E9B6 (/ISS) Q62685 (/ISS)
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
2 Q9Z0Y9 (/IDA) Q9Z0Y9 (/IDA)
Lipid homeostasis GO:0055088
Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.
2 Q9Z0Y9 (/IGI) Q9Z0Y9 (/IGI)
Sterol homeostasis GO:0055092
Any process involved in the maintenance of an internal steady state of sterol within an organism or cell.
2 Q9Z0Y9 (/IMP) Q9Z0Y9 (/IMP)
Triglyceride homeostasis GO:0070328
Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell.
2 Q9Z0Y9 (/IGI) Q9Z0Y9 (/IGI)
Triglyceride homeostasis GO:0070328
Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell.
2 Q9Z0Y9 (/IMP) Q9Z0Y9 (/IMP)
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
2 Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Negative regulation of pancreatic juice secretion GO:0090188
Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.
2 Q9Z0Y9 (/IMP) Q9Z0Y9 (/IMP)
Negative regulation of secretion of lysosomal enzymes GO:0090341
Any process that decreases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.
2 Q9Z0Y9 (/IMP) Q9Z0Y9 (/IMP)
Regulation of intestinal lipid absorption GO:1904729
Any process that modulates the frequency, rate or extent of intestinal lipid absorption.
2 A0A0R4IVP0 (/IMP) Q56A56 (/IMP)
Regulation of nuclear receptor transcription coactivator activity GO:2000325
Any process that modulates the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity.
2 Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
1 Q60644 (/IMP)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
1 Q60644 (/IGI)
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
1 Q62685 (/IEP)
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
1 Q62685 (/IEP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q62755 (/IDA)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q60644 (/ISO)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q62755 (/IDA)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q60644 (/ISO)
Positive regulation of cholesterol efflux GO:0010875
Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
1 Q60644 (/IGI)
Positive regulation of lipid storage GO:0010884
Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
1 Q60644 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 P55055 (/IDA)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 Q60644 (/ISO)
Retinoic acid receptor signaling pathway GO:0048384
The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands.
1 Q62755 (/IDA)
Retinoic acid receptor signaling pathway GO:0048384
The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands.
1 Q60644 (/ISO)
Positive regulation of high-density lipoprotein particle assembly GO:0090108
Any process that increases the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.
1 Q60644 (/IDA)
Positive regulation of pancreatic juice secretion GO:0090187
Any process that increases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.
1 Q60644 (/IMP)
Positive regulation of secretion of lysosomal enzymes GO:0090340
Any process that increases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.
1 Q60644 (/IMP)

There are 15 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
9 P55055 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q60644 (/IDA) Q62685 (/IDA) Q9Z0Y9 (/IDA) Q9Z0Y9 (/IDA)
RNA polymerase II transcription factor complex GO:0090575
A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II.
6 Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q9Z0Y9 (/IDA) Q9Z0Y9 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
5 P55055 (/TAS) Q13133 (/TAS) Q13133 (/TAS) Q13133 (/TAS) Q13133 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS) Q13133 (/ISS) Q5E9B6 (/ISS)
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
4 Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 Q13133 (/TAS) Q13133 (/TAS) Q13133 (/TAS) Q13133 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 P55055 (/IDA) Q62685 (/IDA) Q9Z0Y9 (/IDA) Q9Z0Y9 (/IDA)
Receptor complex GO:0043235
Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
4 Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA) Q13133 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q60644 (/ISO) Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q60644 (/ISO) Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
2 Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q9Z0Y9 (/IMP) Q9Z0Y9 (/IMP)
Receptor complex GO:0043235
Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
2 Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
RNA polymerase II transcription factor complex GO:0090575
A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II.
2 Q9Z0Y9 (/ISO) Q9Z0Y9 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q5E9B6 (/ISS)
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