The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Rho GTPase activation protein
".
FunFam 50: GTPase-activating protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 1 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
|
9 | O74335 (/IDA) P17121 (/IDA) P17121 (/IDA) P17121 (/IDA) P17121 (/IDA) Q12128 (/IDA) Q12128 (/IDA) Q12128 (/IDA) Q12128 (/IDA) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of Rho protein signal transduction GO:0035024
Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction.
|
8 | P17121 (/IGI) P17121 (/IGI) P17121 (/IGI) P17121 (/IGI) Q12128 (/IGI) Q12128 (/IGI) Q12128 (/IGI) Q12128 (/IGI) |
|
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
|
8 | P17121 (/IDA) P17121 (/IDA) P17121 (/IDA) P17121 (/IDA) Q12128 (/IDA) Q12128 (/IDA) Q12128 (/IDA) Q12128 (/IDA) |
|
Regulation of fungal-type cell wall organization GO:0060237
Any process that modulates the rate, frequency or extent of the formation, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
|
5 | A0A1D8PQG5 (/IMP) P17121 (/IMP) P17121 (/IMP) P17121 (/IMP) P17121 (/IMP) |
|
Regulation of actin cytoskeleton organization GO:0032956
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
|
4 | P17121 (/IGI) P17121 (/IGI) P17121 (/IGI) P17121 (/IGI) |
|
Regulation of fungal-type cell wall organization GO:0060237
Any process that modulates the rate, frequency or extent of the formation, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
|
4 | P17121 (/IGI) P17121 (/IGI) P17121 (/IGI) P17121 (/IGI) |
|
Negative regulation of protein kinase C signaling GO:0090038
Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
|
4 | P17121 (/IGI) P17121 (/IGI) P17121 (/IGI) P17121 (/IGI) |
|
Negative regulation of protein kinase C signaling GO:0090038
Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
|
4 | P17121 (/IMP) P17121 (/IMP) P17121 (/IMP) P17121 (/IMP) |
|
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
|
1 | O74335 (/IMP) |
|
Regulation of cell wall (1->3)-beta-D-glucan biosynthetic process GO:0090334
Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.
|
1 | O74335 (/IMP) |
|
Positive regulation of phenotypic switching GO:1900241
Any process that activates or increases the frequency, rate or extent of phenotypic switching.
|
1 | A0A1D8PQG5 (/IMP) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
|
4 | P17121 (/IDA) P17121 (/IDA) P17121 (/IDA) P17121 (/IDA) |
|
Medial cortex GO:0031097
A medial cortical band overlaying the nucleus which acts as a landmark for contractile ring positioning and plays a role in cell cycle regulation.
|
1 | O74335 (/IDA) |
|
Cell tip GO:0051286
The region at the end of the longest axis of a cylindrical or elongated cell.
|
1 | O74335 (/IDA) |
