The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Rho GTPase activation protein
".
FunFam 116: EG:86E4.5 protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
|
2 | O46094 (/ISS) Q95R90 (/ISS) |
|
Phosphatidylinositol bisphosphate phosphatase activity GO:0034593
Catalysis of the reaction: phosphatidylinositol bisphosphate + H2O = phosphatidylinositol phosphate + phosphate.
|
2 | O46094 (/IMP) Q95R90 (/IMP) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitotic cytokinesis GO:0000281
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
|
2 | O46094 (/IMP) Q95R90 (/IMP) |
|
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
|
2 | O46094 (/IMP) Q95R90 (/IMP) |
|
Actomyosin contractile ring localization GO:0032187
The process in which a contractile ring is assembled and/or maintained in a specific location, in the context of cytokinesis that takes place as part of a cell cycle.
|
2 | O46094 (/IMP) Q95R90 (/IMP) |
|
Regulation of GTPase activity GO:0043087
Any process that modulates the rate of GTP hydrolysis by a GTPase.
|
2 | O46094 (/ISS) Q95R90 (/ISS) |
|
Phosphatidylinositol dephosphorylation GO:0046856
The process of removing one or more phosphate groups from a phosphatidylinositol.
|
2 | O46094 (/IMP) Q95R90 (/IMP) |
|
Regulation of cytokinesis, actomyosin contractile ring assembly GO:2000431
Any process that modulates the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly.
|
2 | O46094 (/IMP) Q95R90 (/IMP) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | O46094 (/IDA) Q95R90 (/IDA) |
|
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
|
2 | O46094 (/IDA) Q95R90 (/IDA) |
|
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
|
2 | O46094 (/IDA) Q95R90 (/IDA) |
|
Recycling endosome GO:0055037
An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane.
|
2 | O46094 (/IDA) Q95R90 (/IDA) |
