The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.

The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation.

The movement of a leukocyte within or between different tissues and organs of the body.

A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.

An Fc-gamma receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.

The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin.

Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.

Any process that modulates the surface configuration of a cell.

The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.

Any viral process that modulates the frequency, rate, or extent of the antiviral response of the host cell or organism.

Any series of molecular signals generated as a consequence of binding to a C-type lectin receptor capable of cellular activation.

The process of introducing a phosphate group on to a protein.

The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.

The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.

The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.

Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor (VEGFR) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.

A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).

A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.

The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.

An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst.

The process of introducing a phosphate group on to a protein.

The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.

Behavior associated with the intake of food.

Any process that decreases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.

The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.

Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.

A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.

Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.

The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.

Any process that modulates the frequency, rate or extent of glutamate receptor signaling pathway.

Any process that activates or increases the frequency, rate or extent of neuron death.

Any process that stops, prevents or reduces the frequency, rate or extent of dendritic spine maintenance.

Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced cell death.

Any process that activates or increases the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity.

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamate(1-) stimulus.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus.

Any process that activates or increases the frequency, rate or extent of protein localization to membrane.

Any process that modulates the frequency, rate or extent of calcium ion import across plasma membrane.

Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity.

The process of introducing a phosphate group on to a protein.

Any process that activates or increases the frequency, rate or extent of epithelial cell migration.

The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).

Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.

Any process that activates or increases the frequency, rate or extent of lamellipodium morphogenesis.

Any process that activates or increases the rate or extent of cell proliferation.

The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.

The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

Any process involved in the maintenance of an internal steady state of zinc ions at the level of a cell.

Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process.

Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.

The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.

Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material.

Any process that activates or increases the frequency, rate or extent of T cell activation.

Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway.

Any process involved in the maintenance of an internal steady state of zinc ions at the level of a cell.

Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process.

A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.

Any process that stops, prevents or reduces the rate or extent of cell proliferation.

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.

The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.

The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.

The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.

Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion.

The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.

Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.

Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.

Any process that modulates the extent to which blood vessels can be pervaded by fluid.

A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.

Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.

Any process that activates or increases the frequency, rate or extent of T cell activation.

The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment.

Any process that modulates the frequency, rate or extent of lymphocyte activation.

Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion.

Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway.

The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.

Any process that modulates the frequency, rate, or extent of production of a cytokine.

Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.

A series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.

Tolerance induction directed at self antigens.

The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.

A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response.

A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response.

A series of molecular signals generated as a consequence of the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of inhibiting an immune effector process contributing to an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.

Any process that activates or increases the rate or extent of cell proliferation.

Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.

A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.

Any process that modulates the frequency, rate, or extent of mast cell activation.

Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 2 signaling pathway.

Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.

Any process that modulates the frequency, rate, or extent of mast cell degranulation.

Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.

Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase activity.

The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products.

Any process that modulates the frequency, rate or extent of erythrocyte differentiation.

The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).

A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell.

Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.

Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.

Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.

Any process that stops, prevents or reduces the rate or extent of mast cell proliferation.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.

Any process that modulates the frequency, rate or extent of podosome assembly.

Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.

The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.

Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.

Any process that activates or increases the frequency, rate or extent of actin cytoskeleton reorganization.

Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process.

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst.

Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.

Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.

Tolerance induction directed at self antigens.

The process of introducing a phosphate group on to a protein.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.

A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.

The aggregation, arrangement and bonding together of a set of components to form a complex capable of relaying a signal within a cell.

A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription.

A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.

A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).

Any process that modulates the surface configuration of a cell.

Any process that modulates the frequency, rate or extent of epithelial cell migration.

Any process that decreases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.

Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).

The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.

The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.

Any process that modulates the frequency, rate or extent of attachment of a cell to another cell.

Any process that activates or increases the frequency, rate or extent of cell migration.

Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase.

Any process that stops, prevents, or reduces the frequency, rate or extent of protein homooligomerization.

Any process that activates or increases the frequency, rate, or extent of integrin activation.

Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin.

A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.

Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a molecule.

The process in which a bacterium enters a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.

A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.

A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptors on the surface of a cell, where the signal is transmitted by ERBB2. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB2 receptors are themselves unable to bind to ligands, but act as a signal-amplifying tyrosine kinase within a heterodimeric pair.

Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.

Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.

The aggregation, arrangement and bonding together of a set of components to form a stress fiber. A stress fiber is a contractile actin filament bundle that consists of short actin filaments with alternating polarity.

Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.

Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.

Any process that modulates the frequency, rate or extent of bone tissue loss (resorption).

Any process that modulates the frequency, rate or extent of protein kinase activity.

Any process that activates or increases the frequency, rate or extent of Ras protein signal transduction.

The movement of a macrophage in response to an external stimulus.

Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.

Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material.

Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.

Any series of molecular signals generated as a consequence of a progesterone binding to its receptor.

Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction.

Any process that activates or increases the frequency, rate or extent of the movement of a cellular component.

Any process that stops, prevents, or reduces the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.

Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.

Any process that stops, prevents, or reduces the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.

Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.

The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.

Any process that activates or increases the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.

Any process that activates or increases the rate or extent of mast cell proliferation.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.

Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity.

An angiotensin receptor signaling pathway which contributes to a circulatory system process carried out by the heart.

Any process that modulates the frequency, rate, or extent of monocyte chemotaxis.

Any process that activates or increases the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process.

Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced cell death.

Any process that activates or increases the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamate(1-) stimulus.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus.

Any process that modulates the frequency, rate or extent of early endosome to late endosome transport.

Any process that stops, prevents or reduces the frequency, rate or extent of anoikis.

Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity.

Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway.

Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.

Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway.

Any process that modulates the frequency, rate or extent of caveolin-mediated endocytosis.

The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.

Any process that modulates the frequency, rate, or extent of production of a cytokine.

Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.

Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.

A series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.

Tolerance induction directed at self antigens.

The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response.

The regulated release of histamine by a mast cell or group of mast cells.

The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to activation or perpetuation of an innate immune response.

Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation.