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Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Cyclin-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
2505 - - 97.7
4
494
3D
2pk2D02 - 93.6
2
478 - - 91.9
3
466 - - 97.3
5
433 - - 96.6
6
423 - - 99.5
8
414
3D
5iydM02 - 98.5
9
412
3D
6cytB01 - 81.3
7
411 - - 93.9
10
396 - - 97.4
11
393 - - 77.7
12
373 - - 90.8
13
362 - - 97.2
37
354
3D
4ii5D01 - 92.2
15
352
3D
5xs2B02 - 82.1
14
329 - - 81.8
17
308
3D
5xs2B01 - 82.3
16
290 - - 72.0
18
Predicted
288
3D
6ckxD02 - 82.2
19
276
3D
5iydM01 - 88.4
20
263 - - 77.7
21
Predicted
261
3D
6ckxD01 - 73.0
22
239 - - 84.1
23
235
3D
1d3uB02 - 95.4
24
229
3D
5l2wB01 - 91.8
25
227
3D
3o0gE00 - 69.0
27
212
3D
6gu4B01 - 86.5
26
209 - - 83.3
28
201 - - 78.5
29
195
3D
1kxuA02 - 96.6
30
182 - - 84.3
31
168 - - 91.7
33
168
3D
4ellB02 - 81.1
32
159 - - 95.4
35
150
3D
4yozA01 - 85.8
34
149 - - 88.9
39
131
3D
4ellB01 - 73.1
36
128 - - 75.5
38
119 - - 95.6
40
116 - - 97.8
41
112 - - 63.7
44
112
3D
1kxuA01 - 56.5
42
111 - - 98.3
43
111 - - 85.3
46
110
3D
5n9gF01 - 96.6
45
108 - - 87.8
47
104 - - 84.5
48
102 - - 70.9
49
100 - - 76.5
51
97 - - 70.1
50
97 - - 44.6
52
94 - - 78.1
53
92 - - 85.0
54
91
3D
3m03C00 - 98.0
59
83
3D
4yozA02 - 73.6
55
83 - - 81.9
56
81 - - 72.5
57
81 - - 95.6
60
80 - - 95.5
58
80 - - 75.7
62
79 - - 70.7
61
79 - - 64.0
63
73 - - 70.9
64
67 - - 91.1
65
65 - - 72.1
66
64 - - 79.6
67
62 - - 80.2
68
62 - - 68.5
69
60 - - 91.8
70
57 - - 94.4
71
55 - - 62.1
72
54 - - 80.4
74
53 - - 81.9
73
53 - - 73.8
75
51 - - 77.1
76
51
3D
1zp2A02 - 96.3
77
48 - - 75.2
78
47 - - 68.2
80
46 - - 87.4
79
46 - - 74.8
81
45 - - 84.3
82
43 - - 76.7
85
40
3D
2pmiD00 - 68.6
83
38 - - 76.8
84
37 - - 78.6
86
36 - - 70.0
87
35 - - 25.5
88
34 - - 74.2
89
33 - - 96.1
91
31 - - 75.7
90
31 - - 23.2
94
30 - - 44.5
92
30 - - 45.3
93
30 - - 97.4
96
29 - - 84.0
95
AFU_orthologue AFUA_5G07030
29 - - 93.3
97
28 - - 61.9
99
27 - - 13.3
98
27 - - 48.1
100
26 - - 76.5
101
25 - - 86.2
103
24 - - 91.1
102
24 - - 10.6
120
23
3D
3g33D02 - 73.9
104
23 - - 77.1
105
22 - - 57.3
108
21 - - 89.5
107
21 - - 63.9
106
21 - - 69.2
109
21 - - 74.0
110
21 - - 75.8
111
20 - - 84.7
114
19 - - 71.7
198
19
3D
6gu4B02 - 54.9
113
19 - - 0.0
112
19 - - 49.8
115
18 - - 72.5
116
18 - - 5.2
119
17 - - 5.4
121
17 - - 90.9
118
17 - - 42.1
117
17 - - 66.8
123
16 - - 76.8
127
16 - - 37.2
140
16
3D
5l2wB02 - 39.1
122
16 - - 92.2
125
16 - - 13.0
126
16 - - 72.5
124
16 - - 10.5
130
15 - - 16.6
128
15 - - 65.4
132
15 - - 24.9
131
15 - - 38.2
129
15 - - 25.8
137
14 - - 15.2
141
14 - - 94.3
133
14 - - 30.8
142
14 - - 96.1
138
14 - - 14.0
134
14 - - 79.8
135
14 - - 18.1
139
14 - - 17.9
136
14 - - 7.6
143
Yin
13 - - 13.0
148
13 - - 8.2
147
13 - - 16.2
145
13 - - 46.1
146
13 - - 39.8
150
13 - - 68.5
149
13 - - 13.4
144
13 - - 11.1
154
12 - - 76.0
152
12 - - 26.0
151
12 - - 16.6
153
12 - - 91.7
164
11 - - 45.5
166
11 - - 8.7
177
11
3D
4krdB00 - 1.9
159
11 - - 86.4
156
11 - - 34.6
165
11 - - 74.3
155
11 - - 32.8
162
11 - - 7.3
157
11 - - 70.1
160
11 - - 30.1
167
11 - - 73.8
158
11 - - 34.7
161
11 - - 39.0
168
11 - - 16.5
163
11 - - 10.7
173
10 - - 11.4
171
10 - - 24.1
178
10 - - 7.7
169
10 - - 38.9
170
10 - - 55.1
172
10 - - 25.8
175
10 - - 3.5
179
10 - - 64.4
176
10 - - 79.6
180
10 - - 94.5
181
10 - - 90.0
174
10 - - 11.6
184
9 - - 51.7
189
9 - - 9.4
186
9 - - 6.8
185
9 - - 28.4
182
9 - - 47.5
187
9 - - 11.4
188
9 - - 0.0
183
9 - - 84.0
199
8 - - 77.9
196
8 - - 1.3
195
8 - - 9.2
194
8 - - 12.5
191
8 - - 37.2
193
8 - - 1.3
192
8 - - 84.3
197
8 - - 6.6
190
8 - - 34.6
205
7 - - 14.0
213
7 - - 1.9
211
7 - - 7.5
218
7 - - 42.8
209
7 - - 2.4
206
7 - - 6.8
217
7 - - 7.3
210
7 - - 1.8
204
7 - - 2.3
212
7 - - 44.2
223
7 - - 80.4
203
7 - - 18.6
215
7 - - 0.0
208
7 - - 11.5
201
7 - - 81.5
216
7 - - 9.6
221
7 - - 91.8
219
7 - - 58.4
207
7 - - 2.8
220
7 - - 79.0
200
7 - - 68.9
214
7 - - 4.7
222
7 - - 85.3
202
7 - - 18.9
225
6 - - 75.5
245
6 - - 41.9
229
6 - - 76.6
250
6 - - 76.5
249
6 - - 75.8
246
6 - - 83.1
234
6 - - 8.5
226
6 - - 42.7
235
6 - - 12.9
236
6 - - 5.3
224
6 - - 32.6
244
6 - - 54.5
239
6 - - 3.8
237
6 - - 12.9
243
6 - - 4.6
230
6 - - 70.1
241
6 - - 3.5
228
6 - - 80.2
232
6 - - 5.9
248
6 - - 63.5
240
6 - - 4.5
247
6 - - 72.0
227
6 - - 85.4
233
6 - - 10.9
231
6 - - 96.6
242
6 - - 15.2
238
6 - - 12.6
252
5 - - 43.6
275
5 - - 0.0
262
5 - - 2.4
276
5 - - 0.0
267
5 - - 5.2
279
5 - - 95.5
260
5 - - 1.1
257
5 - - 38.4
261
5 - - 0.0
268
5 - - 2.1
258
5 - - 32.0
251
5 - - 30.5
253
5 - - 63.8
274
5 - - 3.9
263
5 - - 10.6
273
5 - - 14.5
264
5 - - 3.4
254
5 - - 55.4
271
5 - - 0.0
278
5 - - 45.3
256
5 - - 80.5
270
5 - - 4.8
259
5 - - 30.5
269
5 - - 77.5
277
5 - - 25.9
266
5 - - 9.7
272
5 - - 5.0
255
5 - - 78.7
265
5 - - 0.0
282
4 - - 42.3
305
4 - - 11.0
313
4 - - 4.4
291
4 - - 6.8
298
4 - - 29.7
280
4 - - 34.1
293
4 - - 3.4
306
4 - - 0.0
309
4 - - 7.6
311
4 - - 23.2
318
4 - - 82.8
287
4 - - 28.6
292
4 - - 8.0
310
4 - - 5.1
317
4 - - 51.4
288
4 - - 21.9
281
4 - - 42.1
283
4 - - 81.9
290
4 - - 37.9
312
4 - - 1.3
297
4 - - 74.3
304
4 - - 2.7
303
4 - - 6.4
296
4 - - 35.1
315
4 - - 69.1
299
4 - - 92.0
284
4 - - 65.9
319
4 - - 82.1
316
4 - - 43.6
295
4 - - 7.7
308
4 - - 0.0
301
4 - - 34.6
300
4 - - 87.2
286
4 - - 22.1
289
4 - - 33.3
320
4 - - 84.7
307
4 - - 9.3
294
4 - - 4.0
302
4 - - 69.4
285
4 - - 13.0
314
4 - - 12.3
362
3 - - 6.9
325
3 - - 34.5
345
3 - - 9.2
352
3 - - 0.0
360
3 - - 47.8
357
3 - - 14.7
346
3 - - 2.0
326
3 - - 27.8
334
3 - - 2.4
350
3 - - 7.9
367
3 - - 6.2
329
3 - - 0.0
349
3 - - 8.0
358
3 - - 3.1
335
3 - - 0.0
351
3 - - 0.0
361
3 - - 4.7
368
3 - - 55.9
339
3 - - 0.0
374
3 - - 76.4
363
3 - - 0.0
324
3 - - 65.0
336
3 - - 0.0
344
3 - - 0.0
353
3 - - 0.0
354
3 - - 11.2
330
3 - - 0.0
337
3 - - 10.0
323
3 - - 19.4
343
3 - - 2.4
373
3 - - 78.2
364
3 - - 1.1
371
3 - - 63.8
332
3 - - 0.0
328
CAK
3 - - 1.9
341
3 - - 2.7
348
CAK
3 - - 2.0
321
3 - - 29.5
366
3 - - 0.0
347
3 - - 0.0
369
3 - - 33.0
333
3 - - 6.8
327
3 - - 25.4
359
3 - - 7.9
340
3 - - 5.6
370
3 - - 37.6
356
3 - - 43.5
365
3 - - 0.0
355
3 - - 49.4
342
3 - - 6.8
331
3 - - 0.0
338
3 - - 2.6
322
3 - - 46.8
372
3 - - 47.6
391
2 - - 50.9
449
2 - - 6.9
398
2 - - 0.0
480
2 - - 33.6
429
2 - - 0.0
467
2 - - 5.3
450
2 - - 0.0
476
2 - - 40.7
434
2 - - 0.0
479
2 - - 0.0
426
2 - - 12.0
418
2 - - 0.0
446
2 - - 4.7
411
2 - - 10.4
375
2 - - 33.8
409
2 - - 0.0
406
2 - - 0.0
457
2 - - 42.1
460
2 - - 0.0
382
2 - - 37.1
452
2 - - 0.0
445
2 - - 0.0
482
2 - - 41.3
387
2 - - 39.4
425
2 - - 0.0
475
2 - - 29.2
413
2 - - 0.0
405
2 - - 0.0
379
2 - - 40.4
380
2 - - 31.0
376
2 - - 11.6
462
2 - - 0.0
393
2 - - 16.7
388
2 - - 53.4
483
2 - - 38.8
404
2 - - 0.0
381
2 - - 40.1
453
2 - - 40.9
444
2 - - 6.3
436
2 - - 0.0
424
2 - - 0.0
412
2 - - 3.0
392
2 - - 43.8
463
2 - - 1.3
474
2 - - 10.7
439
2 - - 0.0
468
2 - - 2.0
397
2 - - 0.0
461
2 - - 0.0
417
2 - - 2.9
410
2 - - 0.0
481
2 - - 38.5
435
2 - - 0.0
383
2 - - 42.7
451
2 - - 0.0
458
2 - - 13.2
390
2 - - 63.4
384
2 - - 40.8
401
2 - - 0.0
408
2 - - 5.5
448
2 - - 0.0
421
2 - - 0.0
428
2 - - 0.0
432
2 - - 0.9
441
2 - - 0.0
399
2 - - 0.0
416
2 - - 0.0
419
2 - - 10.9
396
2 - - 30.0
478
2 - - 0.0
471
2 - - 0.0
464
2 - - 0.0
473
2 - - 3.6
378
2 - - 33.1
443
2 - - 2.8
423
2 - - 1.7
437
2 - - 0.9
430
2 - - 5.2
395
2 - - 16.8
415
2 - - 0.0
454
2 - - 42.3
403
2 - - 0.0
484
2 - - 44.2
377
2 - - 36.7
394
2 - - 17.1
472
2 - - 0.0
422
2 - - 1.7
438
2 - - 0.0
414
2 - - 2.3
442
2 - - 0.8
455
2 - - 40.6
431
2 - - 0.0
485
2 - - 47.0
465
2 - - 0.4
389
2 - - 39.4
402
2 - - 9.0
386
2 - - 41.3
470
2 - - 0.0
456
2 - - 44.1
486
2 - - 15.3
407
2 - - 0.0
440
2 - - 0.0
459
2 - - 2.7
420
2 - - 0.0
385
2 - - 44.2
427
2 - - 2.0
433
2 - - 0.0
469
2 - - 0.0
447
2 - - 0.8
466
AFU_orthologue AFUA_2G07660
2 - - 1.1
477
2 - - 0.0
400
2 - - 1.1
628
1 - - 0.0
632
1 - - 0.0
493
1 - - 0.0
549
1 - - 0.0
593
1 - - 0.0
616
1 - - 0.0
641
1 - - 0.0
580
1 - - 0.0
648
1 - - 0.0
567
1 - - 0.0
576
1 - - 0.0
550
1 - - 0.0
621
1 - - 0.0
529
1 - - 0.0
671
p130
1 - - 0.0
526
1 - - 0.0
708
1 - - 0.0
534
1 - - 0.0
579
1 - - 0.0
518
1 - - 0.0
619
1 - - 0.0
546
1 - - 0.0
511
1 - - 0.0
678
1 - - 0.0
701
1 - - 0.0
608
1 - - 0.0
719
1 - - 0.0
509
1 - - 0.0
601
1 - - 0.0
487
1 - - 0.0
506
1 - - 0.0
587
1 - - 0.0
716
1 - - 0.0
557
1 - - 0.0
560
1 - - 0.0
695
1 - - 0.0
721
1 - - 0.0
552
1 - - 0.0
545
1 - - 0.0
723
1 - - 0.0
582
1 - - 0.0
525
1 - - 0.0
630
1 - - 0.0
654
1 - - 0.0
575
1 - - 0.0
603
1 - - 0.0
684
1 - - 0.0
615
1 - - 0.0
696
1 - - 0.0
513
1 - - 0.0
703
1 - - 0.0
673
1 - - 0.0
664
1 - - 0.0
505
1 - - 0.0
715
1 - - 0.0
498
1 - - 0.0
598
1 - - 0.0
623
1 - - 0.0
637
1 - - 0.0
562
1 - - 0.0
699
1 - - 0.0
491
1 - - 0.0
591
1 - - 0.0
643
1 - - 0.0
590
1 - - 0.0
490
1 - - 0.0
665
1 - - 0.0
722
1 - - 0.0
504
1 - - 0.0
583
1 - - 0.0
714
1 - - 0.0
553
1 - - 0.0
602
1 - - 0.0
544
1 - - 0.0
672
1 - - 0.0
524
1 - - 0.0
536
1 - - 0.0
702
1 - - 0.0
512
1 - - 0.0
655
1 - - 0.0
642
1 - - 0.0
563
1 - - 0.0
574
1 - - 0.0
539
1 - - 0.0
685
1 - - 0.0
631
1 - - 0.0
622
1 - - 0.0
638
1 - - 0.0
497
1 - - 0.0
597
1 - - 0.0
614
1 - - 0.0
568
1 - - 0.0
720
1 - - 0.0
647
1 - - 0.0
492
1 - - 0.0
592
1 - - 0.0
561
1 - - 0.0
627
1 - - 0.0
669
1 - - 0.0
633
1 - - 0.0
677
1 - - 0.0
666
1 - - 0.0
600
1 - - 0.0
517
1 - - 0.0
694
1 - - 0.0
707
1 - - 0.0
510
1 - - 0.0
700
1 - - 0.0
670
1 - - 0.0
656
1 - - 0.0
607
1 - - 0.0
686
1 - - 0.0
689
TFIIB
1 - - 0.0
581
1 - - 0.0
535
1 - - 0.0
659
1 - - 0.0
620
1 - - 0.0
551
1 - - 0.0
558
1 - - 0.0
640
1 - - 0.0
488
1 - - 0.0
588
1 - - 0.0
711
1 - - 0.0
501
1 - - 0.0
609
1 - - 0.0
508
1 - - 0.0
718
1 - - 0.0
595
1 - - 0.0
495
1 - - 0.0
687
1 - - 0.0
606
1 - - 0.0
660
1 - - 0.0
657
1 - - 0.0
548
1 - - 0.0
680
1 - - 0.0
629
1 - - 0.0
521
1 - - 0.0
650
p107
1 - - 0.0
676
1 - - 0.0
667
1 - - 0.0
532
1 - - 0.0
706
1 - - 0.0
528
1 - - 0.0
541
1 - - 0.0
516
1 - - 0.0
693
1 - - 0.0
649
1 - - 0.0
611
1 - - 0.0
646
1 - - 0.0
519
1 - - 0.0
578
1 - - 0.0
709
1 - - 0.0
679
1 - - 0.0
634
1 - - 0.0
626
1 - - 0.0
571
1 - - 0.0
618
1 - - 0.0
605
1 - - 0.0
564
1 - - 0.0
573
1 - - 0.0
613
1 - - 0.0
596
1 - - 0.0
496
1 - - 0.0
662
1 - - 0.0
543
1 - - 0.0
691
1 - - 0.0
499
1 - - 0.0
599
1 - - 0.0
698
1 - - 0.0
537
1 - - 0.0
523
1 - - 0.0
625
1 - - 0.0
530
1 - - 0.0
645
1 - - 0.0
652
1 - - 0.0
682
1 - - 0.0
705
1 - - 0.0
515
1 - - 0.0
713
1 - - 0.0
554
1 - - 0.0
584
1 - - 0.0
503
1 - - 0.0
675
1 - - 0.0
636
1 - - 0.0
624
1 - - 0.0
612
1 - - 0.0
644
1 - - 0.0
572
1 - - 0.0
538
1 - - 0.0
704
1 - - 0.0
522
1 - - 0.0
514
1 - - 0.0
697
1 - - 0.0
542
1 - - 0.0
555
1 - - 0.0
531
1 - - 0.0
585
1 - - 0.0
639
1 - - 0.0
674
1 - - 0.0
663
1 - - 0.0
683
1 - - 0.0
604
1 - - 0.0
565
1 - - 0.0
653
1 - - 0.0
690
1 - - 0.0
502
1 - - 0.0
712
1 - - 0.0
556
1 - - 0.0
570
1 - - 0.0
717
1 - - 0.0
586
1 - - 0.0
507
1 - - 0.0
610
1 - - 0.0
658
1 - - 0.0
688
1 - - 0.0
540
1 - - 0.0
635
1 - - 0.0
489
1 - - 0.0
681
1 - - 0.0
589
1 - - 0.0
651
1 - - 0.0
520
1 - - 0.0
559
1 - - 0.0
692
1 - - 0.0
533
1 - - 0.0
569
1 - - 0.0
527
1 - - 0.0
661
1 - - 0.0
668
1 - - 0.0
547
1 - - 0.0
594
1 - - 0.0
617
1 - - 0.0
494
1 - - 0.0
566
1 - - 0.0
577
1 - - 0.0
710
1 - - 0.0
500
1 - - 0.0
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