The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Blc2-like
".
FunFam 17: MCL1, BCL2 family apoptosis regulator
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 1 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
6 | A2BF68 (/IPI) Q1L8X3 (/IPI) Q568V1 (/IPI) Q568W5 (/IPI) Q8UWD6 (/IPI) Q9I9N3 (/IPI) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of mitotic nuclear division GO:0007088
Any process that modulates the frequency, rate or extent of mitosis.
|
6 | A2BF68 (/IGI) Q1L8X3 (/IGI) Q568V1 (/IGI) Q568W5 (/IGI) Q8UWD6 (/IGI) Q9I9N3 (/IGI) |
|
Regulation of apoptotic process GO:0042981
Any process that modulates the occurrence or rate of cell death by apoptotic process.
|
6 | A2BF68 (/IGI) Q1L8X3 (/IGI) Q568V1 (/IGI) Q568W5 (/IGI) Q8UWD6 (/IGI) Q9I9N3 (/IGI) |
|
Chordate embryonic development GO:0043009
The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
|
6 | A2BF68 (/IGI) Q1L8X3 (/IGI) Q568V1 (/IGI) Q568W5 (/IGI) Q8UWD6 (/IGI) Q9I9N3 (/IGI) |
|
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
6 | A2BF68 (/IGI) Q1L8X3 (/IGI) Q568V1 (/IGI) Q568W5 (/IGI) Q8UWD6 (/IGI) Q9I9N3 (/IGI) |
|
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154
Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.
|
6 | A2BF68 (/IDA) Q1L8X3 (/IDA) Q568V1 (/IDA) Q568W5 (/IDA) Q8UWD6 (/IDA) Q9I9N3 (/IDA) |
|
Negative regulation of mitotic nuclear division GO:0045839
Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.
|
6 | A2BF68 (/IGI) Q1L8X3 (/IGI) Q568V1 (/IGI) Q568W5 (/IGI) Q8UWD6 (/IGI) Q9I9N3 (/IGI) |
|
Tissue homeostasis GO:0001894
A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function.
|
3 | Q1L8X3 (/IMP) Q568V1 (/IMP) Q9I9N3 (/IMP) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
