The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Ammonium transporter AmtB like domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Ammonium transporter Rh type C

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 15 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ammonium transmembrane transporter activity GO:0008519
Enables the transfer of ammonium from one side of a membrane to the other. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals.
31 O77484 (/ISS) O77608 (/ISS) Q19KI0 (/ISS) Q20CR3 (/ISS) Q3BCQ5 (/ISS) Q3BCQ7 (/ISS) Q4VUI0 (/ISS) Q5NVA3 (/ISS) Q68FT6 (/ISS) Q7TNK7 (/ISS)
(21 more)
Ankyrin binding GO:0030506
Interacting selectively and non-covalently with ankyrin, a 200 kDa cytoskeletal protein that attaches other cytoskeletal proteins to integral membrane proteins.
10 Q19KI0 (/ISS) Q20CR3 (/ISS) Q3BCQ7 (/ISS) Q5NVA3 (/ISS) Q7TNN9 (/ISS) Q96E98 (/ISS) Q9GMG5 (/ISS) Q9UHH0 (/ISS) Q9UHH2 (/ISS) Q9UK70 (/ISS)
Ammonium transmembrane transporter activity GO:0008519
Enables the transfer of ammonium from one side of a membrane to the other. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals.
8 Q02094 (/IDA) Q3BCQ4 (/IDA) Q4VUI0 (/IDA) Q7TNN9 (/IDA) Q8BUX5 (/IDA) Q9H310 (/IDA) Q9QXP0 (/IDA) Q9UBD6 (/IDA)
Leak channel activity GO:0022840
Enables the transport of a solute across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.
4 Q3BCQ5 (/ISS) Q7TNK7 (/ISS) Q9GKN7 (/ISS) Q9QUT0 (/ISS)
Ammonium transmembrane transporter activity GO:0008519
Enables the transfer of ammonium from one side of a membrane to the other. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals.
3 Q8BUX5 (/ISO) Q9QUT0 (/ISO) Q9QXP0 (/ISO)
Ammonium transmembrane transporter activity GO:0008519
Enables the transfer of ammonium from one side of a membrane to the other. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals.
3 Q02094 (/TAS) Q9H310 (/TAS) Q9UBD6 (/TAS)
Ankyrin binding GO:0030506
Interacting selectively and non-covalently with ankyrin, a 200 kDa cytoskeletal protein that attaches other cytoskeletal proteins to integral membrane proteins.
3 Q8BUX5 (/ISO) Q9QUT0 (/ISO) Q9QXP0 (/ISO)
Ammonium transmembrane transporter activity GO:0008519
Enables the transfer of ammonium from one side of a membrane to the other. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals.
2 Q02094 (/IGI) Q9UBD6 (/IGI)
Ankyrin binding GO:0030506
Interacting selectively and non-covalently with ankyrin, a 200 kDa cytoskeletal protein that attaches other cytoskeletal proteins to integral membrane proteins.
2 Q02094 (/IPI) Q9H310 (/IPI)
Leak channel activity GO:0022840
Enables the transport of a solute across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.
1 Q02094 (/IDA)
Leak channel activity GO:0022840
Enables the transport of a solute across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.
1 Q9QUT0 (/ISO)
Ankyrin binding GO:0030506
Interacting selectively and non-covalently with ankyrin, a 200 kDa cytoskeletal protein that attaches other cytoskeletal proteins to integral membrane proteins.
1 Q9UBD6 (/IDA)
Carbon dioxide transmembrane transporter activity GO:0035379
Enables the transfer of carbon dioxide (CO2) from one side of a membrane to the other.
1 Q02094 (/TAS)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q9UBD6 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q9QXP0 (/ISO)

There are 29 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ammonium transport GO:0015696
The directed movement of ammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals.
35 O77484 (/ISS) O77608 (/ISS) Q19KI0 (/ISS) Q20CR3 (/ISS) Q2T9S6 (/ISS) Q3BCQ4 (/ISS) Q3BCQ7 (/ISS) Q4VUI0 (/ISS) Q5NVA3 (/ISS) Q68FT6 (/ISS)
(25 more)
Cellular ion homeostasis GO:0006873
Any process involved in the maintenance of an internal steady state of ions at the level of a cell.
16 O77484 (/ISS) O77608 (/ISS) Q19KI0 (/ISS) Q20CR3 (/ISS) Q3BCQ7 (/ISS) Q5NVA3 (/ISS) Q7TNK7 (/ISS) Q7TNN9 (/ISS) Q9GKN7 (/ISS) Q9GMG1 (/ISS)
(6 more)
Ammonium transport GO:0015696
The directed movement of ammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals.
8 Q02094 (/IDA) Q3BCQ4 (/IDA) Q4VUI0 (/IDA) Q7TNN9 (/IDA) Q8BUX5 (/IDA) Q9H310 (/IDA) Q9QXP0 (/IDA) Q9UBD6 (/IDA)
Ammonium transport GO:0015696
The directed movement of ammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals.
8 A5LHA8 (/IMP) A8E4T4 (/IMP) F1QZM1 (/IMP) Q5TYN0 (/IMP) Q7T067 (/IMP) Q7T070 (/IMP) Q8JI14 (/IMP) Q9QUT0 (/IMP)
Transepithelial ammonium transport GO:0070634
The directed movement of ammonium ions from one side of an epithelium to the other.
5 Q19KI0 (/ISS) Q20CR3 (/ISS) Q3BCQ7 (/ISS) Q5NVA3 (/ISS) Q7TNN9 (/ISS)
Monovalent inorganic cation transport GO:0015672
The directed movement of inorganic cations with a valency of one into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.
4 Q3BCQ5 (/ISS) Q7TNK7 (/ISS) Q9GKN7 (/ISS) Q9QUT0 (/ISS)
Ammonium transmembrane transport GO:0072488
The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+.
4 Q3BCQ5 (/ISS) Q7TNK7 (/ISS) Q9GKN7 (/ISS) Q9QUT0 (/ISS)
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3 A5LHA8 (/IMP) A8E4T4 (/IMP) F1QZM1 (/IMP)
Ammonium transport GO:0015696
The directed movement of ammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals.
3 Q8BUX5 (/ISO) Q9QUT0 (/ISO) Q9QXP0 (/ISO)
Cellular ion homeostasis GO:0006873
Any process involved in the maintenance of an internal steady state of ions at the level of a cell.
2 Q02094 (/IDA) Q9UBD6 (/IDA)
Cellular ion homeostasis GO:0006873
Any process involved in the maintenance of an internal steady state of ions at the level of a cell.
2 Q9QUT0 (/ISO) Q9QXP0 (/ISO)
Ammonium transport GO:0015696
The directed movement of ammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals.
2 Q02094 (/IGI) Q9UBD6 (/IGI)
Urea transport GO:0015840
The directed movement of urea into, out of or within the cell. Urea is the water-soluble compound H2N-CO-NH2.
2 Q5TYN0 (/IMP) Q7T067 (/IMP)
Transepithelial ammonium transport GO:0070634
The directed movement of ammonium ions from one side of an epithelium to the other.
2 Q9H310 (/IDA) Q9UBD6 (/IDA)
Transepithelial ammonium transport GO:0070634
The directed movement of ammonium ions from one side of an epithelium to the other.
2 Q8BUX5 (/ISO) Q9QXP0 (/ISO)
Ammonia homeostasis GO:0097272
Any biological process involved in the maintenance of an internal steady state of ammonia.
2 Q7T070 (/IMP) Q8JI14 (/IMP)
Regulation of pH GO:0006885
Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell.
1 Q9QXP0 (/IMP)
Carbon dioxide transport GO:0015670
The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q02094 (/IDA)
Carbon dioxide transport GO:0015670
The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q9QUT0 (/ISO)
Monovalent inorganic cation transport GO:0015672
The directed movement of inorganic cations with a valency of one into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.
1 Q02094 (/IDA)
Monovalent inorganic cation transport GO:0015672
The directed movement of inorganic cations with a valency of one into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.
1 Q9QUT0 (/ISO)
Bicarbonate transport GO:0015701
The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q02094 (/TAS)
Amine transport GO:0015837
The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q9UBD6 (/NAS)
Epithelial cell differentiation GO:0030855
The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium.
1 Q9UBD6 (/NAS)
Homeostatic process GO:0042592
Any biological process involved in the maintenance of an internal steady state.
1 Q9UBD6 (/NAS)
Erythrocyte development GO:0048821
The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure.
1 Q9QUT0 (/IMP)
Multicellular organismal iron ion homeostasis GO:0060586
Any process involved in the maintenance of the distribution of iron stores within tissues and organs of a multicellular organism.
1 Q9QUT0 (/IMP)
Ammonium transmembrane transport GO:0072488
The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+.
1 Q02094 (/IMP)
Ammonium transmembrane transport GO:0072488
The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+.
1 Q9QUT0 (/ISO)

There are 31 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
19 Q19KI0 (/ISS) Q20CR3 (/ISS) Q3BCQ7 (/ISS) Q4VUI0 (/ISS) Q5NVA3 (/ISS) Q68FT6 (/ISS) Q7TNN9 (/ISS) Q8WMW0 (/ISS) Q8WMW2 (/ISS) Q8WNQ5 (/ISS)
(9 more)
Spectrin-associated cytoskeleton GO:0014731
The part of the cytoskeleton composed of spectrin, protein 4.1 and ankyrin. Spectrin-associated cytoskeleton is associated with the plasma membrane.
14 Q4VUI0 (/ISS) Q68FT6 (/ISS) Q8BUX5 (/ISS) Q8WMW0 (/ISS) Q8WMW2 (/ISS) Q8WNQ5 (/ISS) Q8WNQ6 (/ISS) Q95JD4 (/ISS) Q95M74 (/ISS) Q95M74 (/ISS)
(4 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
10 O77484 (/ISS) Q3BCQ5 (/ISS) Q7TNK7 (/ISS) Q9GKN7 (/ISS) Q9GMG1 (/ISS) Q9GMG2 (/ISS) Q9GMG4 (/ISS) Q9GMG5 (/ISS) Q9GMG6 (/ISS) Q9QUT0 (/ISS)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
10 Q19KI0 (/ISS) Q20CR3 (/ISS) Q2T9S6 (/ISS) Q3BCQ4 (/ISS) Q3BCQ7 (/ISS) Q5NVA3 (/ISS) Q6WRY0 (/ISS) Q6XL41 (/ISS) Q7TNN9 (/ISS) Q95JD3 (/ISS)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
8 Q19KI0 (/ISS) Q20CR3 (/ISS) Q2T9S6 (/ISS) Q3BCQ4 (/ISS) Q3BCQ7 (/ISS) Q5NVA3 (/ISS) Q95JD3 (/ISS) Q9UBD6 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
6 Q02094 (/IDA) Q3BCQ4 (/IDA) Q4VUI0 (/IDA) Q9H310 (/IDA) Q9QXP0 (/IDA) Q9UBD6 (/IDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
6 Q19KI0 (/ISS) Q20CR3 (/ISS) Q3BCQ7 (/ISS) Q5NVA3 (/ISS) Q7TNN9 (/ISS) Q8BUX5 (/ISS)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
6 Q4VUI0 (/IDA) Q68FT6 (/IDA) Q7TNN9 (/IDA) Q8BUX5 (/IDA) Q9H310 (/IDA) Q9UBD6 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
4 Q3BCQ5 (/ISS) Q7TNK7 (/ISS) Q9GKN7 (/ISS) Q9QUT0 (/ISS)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
3 A8QJ79 (/IDA) B6D1P3 (/IDA) Q4VUZ1 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 Q8BUX5 (/ISO) Q9QUT0 (/ISO) Q9QXP0 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 Q02094 (/TAS) Q9H310 (/TAS) Q9UBD6 (/TAS)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
3 Q7TNN9 (/IDA) Q9QXP0 (/IDA) Q9UBD6 (/IDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 Q9H310 (/IDA) Q9UBD6 (/IDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 Q8BUX5 (/ISO) Q9QXP0 (/ISO)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 Q02094 (/IDA) Q8BUX5 (/IDA)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
2 Q8BUX5 (/ISO) Q9QXP0 (/ISO)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q02094 (/TAS)
Basal plasma membrane GO:0009925
The region of the plasma membrane located at the basal end of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
1 Q7TNN9 (/IDA)
Basal plasma membrane GO:0009925
The region of the plasma membrane located at the basal end of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
1 Q9QXP0 (/ISO)
Spectrin-associated cytoskeleton GO:0014731
The part of the cytoskeleton composed of spectrin, protein 4.1 and ankyrin. Spectrin-associated cytoskeleton is associated with the plasma membrane.
1 Q9H310 (/IMP)
Spectrin-associated cytoskeleton GO:0014731
The part of the cytoskeleton composed of spectrin, protein 4.1 and ankyrin. Spectrin-associated cytoskeleton is associated with the plasma membrane.
1 Q8BUX5 (/ISO)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q9QUT0 (/ISO)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q8JI14 (/ISS)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
1 Q9QXP0 (/ISO)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
1 Q7TNN9 (/IDA)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
1 Q9QXP0 (/ISO)
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
1 A8QJ81 (/IDA)
Anchored component of plasma membrane GO:0046658
The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
1 Q9H310 (/IMP)
Anchored component of plasma membrane GO:0046658
The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
1 Q8BUX5 (/ISO)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 Q9UBD6 (/HDA)
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