CATH Superfamily 1.10.287.130

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
1	Two-component sensor histidine kinase	1043	3D	4zkiB01	-	98.5
2	Two-component osmosensing histidine kinase	618		-	-	95.6
3	Histidine kinase	529		-	-	91.6
4	Ethylene receptor 1	442	3D	4mtxD00	-	97.9
6	Osmolarity two-component histidine kinase EnvZ	425	3D	3zrwC00	-	71.4
5	Nitrogen regulation histidine kinase	417		-	-	63.6
8	Two-component sensor histidine kinase	320	3D	6azrC01	-	96.6
7	Sensor histidine kinase CpxA	316	3D	4biuE01	-	51.1
9	Two-component sensor histidine kinase	298		-	-	76.1
10	Two-component sensor histidine kinase	295		-	-	84.8
11	Sensor histidine kinase DcuS	292		-	-	93.8
12	Histidine kinase	266		-	-	54.0
13	Sensor histidine kinase PhoQ	245		-	-	78.6
14	Signal transduction histidine-protein kinase BaeS	195		-	-	70.8
15	Histidine kinase 4	178		-	-	74.2
16	Aerobic respiration control sensor protein	175		-	-	41.1
17	Two-component sensor histidine kinase	132		-	-	32.0
19	Sensor histidine kinase RcsC	124		-	-	35.1
18	Sensor histidine kinase RstB	124		-	-	28.4
20	Sensor histidine kinase DpiB	116		-	-	30.5
21	Sensor histidine kinase KdpD	110		-	-	80.3
22	Two-component sensor CbrA	101		-	-	37.2
23	Sensor histidine kinase/response regulator, putative	99		-	-	90.8
24	Sensor histidine kinase/response regulator	96		-	-	23.2
25	Histidine kinase 1-like protein	94		-	-	81.4
26	Two-component system sensor histidine kinase PmrB	89		-	-	54.7
27	Sensor histidine kinase KdpD	88		-	-	70.2
29	Phytochrome	88		-	-	71.5
28	Hybrid signal transduction histidine kinase	88		-	-	72.8
30	Putative histidine kinase 5	86		-	-	74.2
31	Two-component sensor histidine kinase	84		-	-	71.9
33	Sporulation initiation phosphotransferase	83		-	-	12.4
32	Sensor histidine kinase	83		-	-	61.3
34	Two-component system sensor histidine kinase/response regulator	82		-	-	97.6
35	Two-component sensor histidine kinase	79		-	-	95.1
36	Two-component sensor histidine kinase	78		-	-	78.3
37	Hybrid sensor histidine kinase/response regulator	72	3D	5idjA01	-	84.8
38	Sensory transduction histidine kinase	67		-	-	95.4
39	Sensor-like histidine kinase YfhK	61		-	-	90.8
40	PAS domain-containing sensor histidine kinase	60		-	-	84.2
43	Two-component sensor histidine kinase KdpD	59		-	-	23.6
44	LAO/AO transport system ATPase	59	3D	2p67A03	-	12.4
41	Two-component sensor histidine kinase	59		-	-	30.7
42	Sensor protein	59		-	-	1.0
45	Two-component system sensor histidine kinase/response regulator	57		-	-	89.9
46	Two-component sensor histidine kinase	56		-	-	54.2
47	Two-component sensor histidine kinase	56		-	-	61.5
49	C4-dicarboxylate transport sensor protein DctB	55		-	-	97.1
48	Sensor histidine kinase/response regulator	55		-	-	62.2
50	Related to histidine kinase	54		-	-	73.1
51	Two-component system sensor histidine kinase CreC	54		-	-	63.9
58	Histidine phosphotransferase ChpT	49	3D	4fppC01	-	60.9
52	PAS domain-containing sensor histidine kinase	49		-	-	39.3
53	Two-component sensor histidine kinase	46		-	-	33.5
55	Two-component sensor histidine kinase	46	3D	4gczB02	-	75.2
54	Sensor histidine kinase	45		-	-	33.8
56	Sensor histidine kinase	42		-	-	27.5
57	Type IV pilus sensor protein PilS	40		-	-	62.7
59	PAS domain-containing sensor histidine kinase	36		-	-	31.8
61	Histidine kinase	35		-	-	76.0
60	ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein	35		-	-	37.1
62	Hybrid sensor histidine kinase/response regulator	34		-	-	25.8
67	Methylmalonic aciduria type A homolog, mitochondrial	34	3D	2wwwD03	-	41.6
63	Hybrid sensor histidine kinase/response regulator	34		-	-	86.8
65	Histidine kinase	33		-	-	58.5
64	Sensor histidine kinase	33		-	-	16.7
66	PAS domain-containing sensor histidine kinase	31		-	-	77.2
68	PAS domain-containing sensor histidine kinase	30		-	-	89.9
70	Histidine kinase sensor protein	29		-	-	86.8
69	Probable histidine kinase 1	29		-	-	17.7
72	Hybrid sensor histidine kinase/response regulator	28		-	-	26.0
71	Sensor histidine kinase	28		-	-	5.0
73	Two-component sensor histidine kinase	26		-	-	79.8
74	Histidine kinase	26		-	-	64.1
75	Two-component sensor histidine kinase	24		-	-	31.0
77	Sensor histidine kinase SaeS	23		-	-	10.8
80	Sensor histidine kinase/response regulator EvgS	23		-	-	69.2
76	Two-component sensor histidine kinase	23		-	-	17.5
79	Unplaced genomic scaffold supercont1.240, whole genome shotgun sequence	23		-	-	73.7
78	Heme sensor histidine kinase HssS	23		-	-	1.9
81	Hybrid sensor histidine kinase/response regulator	20		-	-	91.2
84	Sensor histidine kinase	19		-	-	0.0
83	Putative two-component sensor histidine kinase	19		-	-	57.6
85	Signal transduction histidine-protein kinase atoS	19		-	-	1.6
87	Ethylene receptor 4	19		-	-	97.5
82	Sensor histidine kinase YvrG	19		-	-	72.3
86	Two-component system sensor histidine kinase/response regulator	19		-	-	45.1
88	Two-component sensor histidine kinase	18		-	-	40.8
89	Sensor histidine kinase	18		-	-	85.3
92	Response regulator receiver domain protein	17		-	-	44.4
103	Two-component sensor histidine kinase	17	3D	4q20B01	-	27.8
90	Histidine kinase sensor protein	17		-	-	16.0
91	Autoinducer 2 sensor kinase/phosphatase LuxQ	17		-	-	80.8
95	Two-component sensor histidine kinase	16		-	-	18.9
93	Two-component sensor histidine kinase	16		-	-	8.9
94	Two-component sensor histidine kinase	16		-	-	4.2
96	Two-component sensor histidine kinase	14		-	-	30.7
97	Sensor histidine kinase	14		-	-	18.0
99	Two-component sensor histidine kinase	14		-	-	11.9
101	Sensor histidine kinase	14		-	-	87.0
98	Histidine kinase	14		-	-	25.0
100	Sensor histidine kinase/response regulator	14		-	-	78.5
105	Putative sensory histidine kinase in two-component regulatory system	13		-	-	0.0
104	Sensor histidine kinase	13		-	-	0.0
107	Sensor histidine kinase YycG	13		-	-	79.4
102	Two-component sensor histidine kinase	13		-	-	27.9
106	Hybrid sensor histidine kinase/response regulator	13		-	-	7.4
108	Two-component sensor histidine kinase	12		-	-	19.1
109	Sensor histidine kinase	12		-	-	30.0
110	Two-component system sensor histidine kinase/response regulator	12		-	-	52.1
113	PAS/PAC sensor hybrid histidine kinase	11		-	-	76.1
111	Two-component sensor histidine kinase	11		-	-	20.1
112	Sensor histidine kinase	11		-	-	15.1
121	Histidine kinase sensor protein	10		-	-	81.3
115	Histidine kinase	10		-	-	14.8
120	RteA, two-component system histidine kinase, with response regulator receiver domain	10		-	-	71.2
114	Sensor histidine kinase RegB	10		-	-	29.5
118	Hybrid sensor histidine kinase/response regulator	10		-	-	23.1
119	Unplaced genomic scaffold supercont1.240, whole genome shotgun sequence	10		-	-	13.3
116	Sensor histidine kinase	10		-	-	0.0
117	Sensor histidine kinase	10		-	-	11.7
126	Related to SLN1-histidine kinase osmosensor that regulates a MAP kinase cascade	9		-	-	17.5
127	Two-component sensor histidine kinase	9		-	-	79.5
122	Sensor histidine kinase	9		-	-	23.9
124	Two-component system, OmpR family, sensor histidine kinase KdpD	9		-	-	47.7
123	Probable two-component sensor	9		-	-	0.0
128	Sensory box sensor histidine kinase	9		-	-	41.3
125	Signal transduction histidine kinase	9		-	-	39.9
133	Sensory box sensor histidine kinase	8		-	-	10.1
129	Two-component sensor, ParS	8		-	-	0.0
132	Sensory transduction histidine kinase	8		-	-	39.1
131	Sensor histidine kinase	8		-	-	24.3
130	Signal transduction histidine kinase	8		-	-	14.3
144	Two-component sensor histidine kinase	7		-	-	77.2
143	Two-component system sensor histidine kinase	7		-	-	12.5
134	Two-component sensor histidine kinase	7		-	-	0.0
138	Sensor histidine kinase	7		-	-	4.2
145	Sensory transduction histidine kinase	7		-	-	86.0
135	Sensor histidine kinase	7		-	-	1.1
137	Sensor histidine kinase YbdK	7		-	-	27.6
141	Sensor histidine kinase, KdpD	7		-	-	0.0
140	Sensor histidine kinase, PAS and GAF domain-containing	7		-	-	83.5
136	Histidine kinase	7		-	-	72.7
142	Sensor histidine kinase	7		-	-	0.0
139	Sensor histidine kinase	7		-	-	0.0
148	Two-component sensor EnvZ	6		-	-	0.0
159	Two-component sensor histidine kinase	6		-	-	52.0
151	Sensor histidine kinase KdpD	6		-	-	4.5
156	Probable two-component sensor	6		-	-	4.8
150	Two-component system sensor histidine kinase	6		-	-	0.0
157	Two-component system sensor protein	6		-	-	1.7
152	Sensor histidine kinase	6		-	-	17.1
155	Histidine kinase, putative	6		-	-	17.1
146	PAS domain S-box protein	6		-	-	0.0
147	Protein-histidine kinase, putative	6		-	-	8.2
154	Adaptive-response sensory kinase	6		-	-	81.4
158	Hybrid sensor histidine kinase/response regulator	6		-	-	70.3
149	Sensor histidine kinase	6		-	-	0.0
153	Sensor histidine kinase	6		-	-	11.0
167	Sensor histide kinase	5		-	-	0.0
162	Two component system histidine kinase	5		-	-	15.4
161	Histidine kinase A domain protein	5		-	-	7.7
179	GAF sensor signal transduction histidine kinase	5		-	-	53.1
166	Two-component sensor histidine kinase	5		-	-	3.1
160	Two-component system, OmpR family, sensor kinase	5		-	-	6.2
177	Hybrid sensor histidine kinase/response regulator	5		-	-	1.9
172	Two-component hybrid sensor and regulator	5		-	-	5.4
171	Integral membrane sensor signal transduction histidine kinase	5		-	-	18.5
176	Development and carotenogenesis control-1 protein	5		-	-	5.7
170	Volvoxopsin-5, sensory rhodopsin with histidine kinase domain	5		-	-	2.5
169	Sensor histidine kinase	5		-	-	12.6
164	Signal transduction histidine kinase	5		-	-	19.1
175	Sensory box histidine kinase SdeK	5		-	-	11.3
168	Sensor histidine kinase	5		-	-	0.0
163	Sensor histidine kinase	5		-	-	9.0
180	Two-component hybrid sensor and regulator	5		-	-	78.8
165	Two-component hybrid sensor and regulator	5		-	-	10.0
174	Sensory box histidine kinase	5		-	-	5.4
173	Sensor histidine kinase/response regulator LuxN	5		-	-	11.9
178	Sensory transduction histidine kinase	5		-	-	40.0
185	Bacteriophytochrome protein	4		-	-	15.6
184	Sensor histidine kinase	4		-	-	1.9
183	Histidine kinase	4		-	-	6.2
188	Sensor protein atoS	4		-	-	7.7
193	Sensory transduction histidine kinase	4		-	-	65.8
194	Sensor histidine kinase, PAS, PAS and PAS domain-containing	4		-	-	36.3
189	Sensory box sensor histidine kinase/response regulator VieS	4		-	-	1.8
181	HAMP domain-containing histidine kinase	4		-	-	0.0
192	Histidine kinase	4		-	-	50.8
186	Bacteriophytochrome	4		-	-	0.0
187	PAS domain-containing sensor histidine kinase	4		-	-	0.0
190	Sensor histidine kinase/response regulator	4		-	-	8.1
191	Histidine kinase	4		-	-	6.3
182	Histidine kinase sensor protein	4		-	-	3.3
205	Two-component sensor histidine kinase	3		-	-	0.0
195	Hybrid sensory kinase	3		-	-	10.6
213	Hybrid sensory kinase	3		-	-	7.9
214	Histidine kinase	3		-	-	54.5
208	Two-component hybrid sensor and regulator	3		-	-	3.1
198	Sensor histidine kinase	3		-	-	7.1
203	Hybrid sensor kinase RscS	3		-	-	7.5
204	Sensor histidine kinase	3		-	-	13.4
199	Two component signal transduction system histidine kinase	3		-	-	6.3
209	Integral membrane sensor signal transduction histidine kinase	3		-	-	11.9
210	Sensor histidine kinase	3		-	-	44.8
202	Integral membrane sensor signal transduction histidine kinase	3		-	-	6.8
211	Two-component sensor histidine kinase	3		-	-	0.0
197	Sensor protein	3		-	-	2.0
207	GAF sensor signal transduction histidine kinase	3		-	-	8.2
196	Histidine kinase	3		-	-	0.0
200	Probable two-component sensor histidine kinase VicK	3		-	-	9.9
206	HAMP domain protein	3		-	-	2.1
212	Two-component hybrid sensor and regulator	3		-	-	1.2
201	Phosphate regulon sensor protein PhoR SphS	3		-	-	3.1
243	Histidine kinase	2		-	-	0.0
226	Two component system histidine kinase	2		-	-	1.4
248	Hybrid sensory kinase	2		-	-	0.0
220	Sensor histidine kinase	2		-	-	0.0
221	Two-component system sensor histidine kinase	2		-	-	0.0
215	Sensory box histidine kinase	2		-	-	7.1
244	Uncharacterized protein	2		-	-	0.0
222	Hybrid signal transduction histidine kinase C	2		-	-	1.7
238	Circadian input kinase A	2		-	-	10.3
233	Histidine kinase	2		-	-	0.0
234	Sensor histidine kinase, Cache_1 and HAMP domain-containing	2		-	-	5.7
227	Two-component sensor kinase	2		-	-	2.1
250	Response receiver histidine kinase	2		-	-	0.0
229	Sensor histidine kinase	2		-	-	1.5
218	Ethylene response sensor 1	2		-	-	0.0
251	Hybrid sensory kinase	2		-	-	0.0
245	Sensory box sensor histidine kinase	2		-	-	4.5
252	ATP-binding region ATPase domain protein	2		-	-	47.7
235	Regulatory components of sensory transduction system	2		-	-	0.0
232	Globin-coupled histidine kinase	2		-	-	8.8
228	Sensory transduction histidine kinase	2		-	-	8.1
240	Histidine kinase	2		-	-	0.0
219	Sensory transduction histidine kinase	2		-	-	0.0
246	Uncharacterized protein	2		-	-	11.1
223	GAF domain-containing protein	2		-	-	0.0
224	Histidine kinase	2		-	-	4.9
241	Sensor histidine kinase	2		-	-	0.0
237	Phytochrome-like protein cph1	2		-	-	0.0
236	Sensor histidine kinase, PAS and GAF domain-containing	2		-	-	0.0
230	Sensor histidine kinase, HAMP domain-containing	2		-	-	9.4
242	Sensor histidine kinase, PAS domain-containing	2		-	-	0.0
247	Hybrid signal transduction histidine kinase H	2		-	-	8.9
231	ATP-binding region ATPase domain protein	2		-	-	0.0
249	Two-component hybrid sensor and regulator	2		-	-	1.4
216	Two-component system sensor protein	2		-	-	0.0
225	Two-component hybrid sensor and regulator	2		-	-	0.0
239	Two component signal transduction system histidine kinase with CHASE and PAS sensory domains	2		-	-	10.3
217	Sensor histidine kinase, NtrB-related protein	2		-	-	0.0
259	Histidine kinase	1		-	-	0.0
262	Histidine kinase sensor protein	1		-	-	0.0
267	Periplasmic substrate-binding histidine kinase	1		-	-	0.0
266	Putative two-component system sensor kinase/response regulator	1		-	-	0.0
260	Two-component sensor histidine kinase	1		-	-	0.0
261	Phosphate regulon sensor protein PhoR	1		-	-	0.0
256	Sensor histidine kinase	1		-	-	0.0
272	BfiS	1		-	-	0.0
269	Uncharacterized protein	1		-	-	0.0
270	Sensory histidine protein kinase	1		-	-	0.0
257	Histidine kinase	1		-	-	0.0
271	Sensor histidine kinase, PAS domain-containing	1		-	-	0.0
255	Two-component hybrid sensor and regulator	1		-	-	0.0
263	Sensor histidine kinase, copper metabolism, putative	1		-	-	0.0
268	Sensor histidine kinase/response regulator	1		-	-	0.0
264	Two component system histidine kinase	1		-	-	0.0
253	Two component signal transduction system histidine kinase	1		-	-	0.0
258	Sensor histidine kinase	1		-	-	0.0
254	Histidine kinase A domain protein	1		-	-	0.0
273	Two-component hybrid sensor and regulator	1		-	-	0.0
265	Histidine kinase	1		-	-	0.0