×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
DnaJ domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
779
3D
2guzO00 - 96.1
2
603
3D
2qwrB00 - 96.9
3
468 - - 72.7
4
Hsp40
391 - - 83.3
6
376
3D
2guzP00 - 98.9
5
Hsp40
372 - - 79.0
7
Hsp40
357 - - 87.1
8
342
3D
1fpoC01 - 79.5
9
305 - - 85.6
10
283 - - 40.8
11
277 - - 79.3
12
262 - - 78.4
13
260 - - 29.1
14
254 - - 95.4
15
217 - - 82.3
16
Hsp40
214 - - 89.9
17
209
3D
2n05A00 - 75.2
18
Hsp40
184 - - 72.6
19
184
3D
2ys8A00 - 85.3
20
178 - - 92.3
21
Hsp40
174
3D
2lgwA00 - 82.6
22
164 - - 72.2
23
155
3D
1iurA01 - 36.2
24
Hsp40
153 - - 50.1
25
148 - - 72.9
26
144 - - 72.9
27
Hsp40
144 - - 80.7
29
143
3D
3apqB01 - 71.8
28
142 - - 87.0
30
133 - - 73.2
31
131 - - 88.1
32
129 - - 76.3
34
128
3D
4j7zF00 - 94.2
33
127 - - 89.4
35
122 - - 88.8
36
118
3D
2qsaA00 - 87.5
37
113 - - 80.5
38
106 - - 82.8
39
Npl1
103 - - 93.0
40
100 - - 67.4
41
99 - - 94.4
42
86
3D
3bvoB01 - 85.9
43
85
3D
3ag7A00 - 83.3
44
Hsp40
83 - - 53.1
45
82 - - 76.8
46
82 - - 87.3
47
80 - - 74.4
48
79 - - 85.4
49
79
3D
2ctqA01 - 67.6
50
77 - - 75.9
51
77 - - 39.7
52
73 - - 88.8
53
69 - - 87.8
54
67
3D
2ctrA00 - 68.6
56
Hsp40
65
3D
2l6lA01 - 90.7
55
64 - - 90.2
57
61 - - 38.6
58
59 - - 79.6
59
57 - - 85.4
60
Hsp40
55
3D
2yuaA01 - 81.3
62
53 - - 70.6
63
53 - - 91.6
61
Hsp40
53 - - 30.1
64
52 - - 77.9
66
51 - - 77.1
65
51 - - 71.9
67
50 - - 74.5
68
43 - - 67.9
69
40 - - 83.6
70
40 - - 91.5
71
39 - - 70.4
72
38 - - 85.6
73
35 - - 93.2
74
30 - - 75.1
75
29 - - 76.7
77
28 - - 86.8
76
28 - - 88.3
82
27 - - 89.0
81
27 - - 86.2
79
27 - - 75.0
78
27 - - 72.7
80
NAD
P
27 - - 75.0
83
26 - - 70.3
84
25 - - 68.6
87
24 - - 89.6
88
24 - - 13.6
89
24 - - 63.2
86
24 - - 68.6
92
24
3D
4rwuA00 - 56.8
85
24 - - 61.6
90
23 - - 80.2
95
22 - - 83.8
109
22
3D
3uo3B01 - 70.1
91
22 - - 82.8
94
22 - - 65.8
93
22 - - 80.8
96
21 - - 80.7
99
20 - - 63.7
98
20 - - 83.1
100
20 - - 74.7
97
20 - - 74.8
101
19 - - 55.3
103
19 - - 67.3
106
19 - - 88.8
104
19 - - 54.9
105
19 - - 35.7
102
19 - - 15.9
110
AFU_orthologue AFUA_2G13210
18 - - 86.8
108
18 - - 2.0
107
18 - - 80.6
113
Hsp40
17 - - 90.6
119
17 - - 68.9
116
17 - - 82.8
111
17 - - 10.2
117
17 - - 5.4
112
17 - - 81.0
114
17 - - 74.6
115
17 - - 74.9
118
17 - - 7.7
122
16 - - 0.0
124
16 - - 71.0
125
16 - - 58.5
120
16 - - 48.2
121
16 - - 11.3
123
16 - - 6.3
127
15 - - 14.1
128
15 - - 7.0
161
15
3D
1gh6A01 - 81.1
126
15 - - 32.6
129
14 - - 89.2
130
Caj1
14 - - 80.3
134
13 - - 4.0
135
13 - - 72.9
138
13 - - 41.7
137
13 - - 72.4
132
13 - - 9.2
133
13 - - 1.3
136
13 - - 57.9
131
13 - - 2.6
142
12 - - 76.1
139
12 - - 67.9
141
12 - - 47.1
140
12 - - 88.9
143
12 - - 70.3
148
11 - - 2.6
145
11 - - 66.1
144
11 - - 77.2
151
11 - - 50.7
150
11 - - 7.7
147
11 - - 40.9
153
11 - - 49.1
152
11 - - 70.6
146
11 - - 42.5
149
11 - - 32.0
156
10 - - 13.4
160
10 - - 55.9
159
10 - - 73.3
158
10 - - 83.4
155
10 - - 38.6
154
10 - - 73.5
157
10 - - 0.0
163
9 - - 44.5
166
9 - - 40.4
164
9 - - 18.9
165
9 - - 9.5
162
9 - - 18.1
170
8 - - 63.1
171
8 - - 25.7
176
8 - - 46.2
173
8 - - 59.4
169
8 - - 35.2
172
8 - - 1.8
177
Hsp40
8 - - 60.3
168
8 - - 13.4
167
8 - - 39.7
175
8 - - 73.7
174
8 - - 6.7
179
Prokaryotic heat shock protein
7 - - 33.8
186
7 - - 14.4
189
7 - - 69.7
183
7 - - 6.3
190
7 - - 81.7
180
7 - - 57.6
181
7 - - 41.4
185
7 - - 10.0
184
7 - - 9.0
188
7 - - 74.1
187
7 - - 75.1
178
7 - - 9.1
182
7 - - 43.1
203
6 - - 64.9
201
6 - - 21.0
200
6 - - 1.7
196
Hsp40
6 - - 5.5
199
DnaJ family
6 - - 10.7
193
6 - - 50.2
191
6 - - 38.9
195
6 - - 79.2
194
6 - - 74.2
198
6 - - 0.0
202
6 - - 10.3
197
6 - - 4.5
204
6 - - 61.4
192
6 - - 28.7
209
5 - - 11.4
206
5 - - 72.1
210
5 - - 11.9
211
5 - - 13.6
219
5 - - 1.1
213
5 - - 6.0
222
5 - - 86.9
216
5 - - 18.6
218
5 - - 13.3
207
5 - - 75.9
214
5 - - 11.4
215
5 - - 8.2
223
5 - - 80.4
212
5 - - 15.1
205
5 - - 73.9
221
5 - - 71.3
220
Hsp40
5 - - 64.2
217
Hsp40
5 - - 36.7
208
5 - - 15.3
247
4 - - 31.0
224
4 - - 84.1
232
4 - - 39.7
225
4 - - 15.3
242
4 - - 12.7
237
4 - - 6.9
250
4 - - 64.2
251
4 - - 55.5
228
4 - - 36.7
245
4 - - 56.3
244
4 - - 67.6
238
4 - - 0.0
227
4 - - 58.7
234
4 - - 44.0
248
4 - - 50.8
235
4 - - 84.0
246
Prokaryotic heat shock protein
4 - - 17.8
230
4 - - 69.0
231
4 - - 60.7
249
4 - - 70.0
243
4 - - 11.6
239
4 - - 0.0
233
4 - - 45.3
240
4 - - 8.3
236
4 - - 80.0
241
4 - - 0.0
229
4 - - 66.9
226
4 - - 34.3
256
3 - - 27.0
260
3 - - 7.7
261
3 - - 12.1
281
3 - - 5.3
259
3 - - 8.0
253
3 - - 15.9
280
3 - - 51.2
269
3 - - 6.9
286
3 - - 41.7
263
3 - - 1.2
283
3 - - 36.5
266
3 - - 5.2
276
3 - - 1.0
273
3 - - 35.7
279
3 - - 2.8
271
3 - - 3.9
270
3 - - 10.0
282
3 - - 34.0
257
3 - - 36.1
275
3 - - 9.4
262
3 - - 9.5
274
3 - - 56.2
252
3 - - 49.8
287
3 - - 70.1
278
3 - - 2.4
267
3 - - 0.0
255
3 - - 31.4
277
3 - - 0.0
288
3 - - 56.4
254
3 - - 4.6
268
3 - - 12.8
264
3 - - 1.2
272
3 - - 5.0
258
3 - - 80.7
285
3 - - 42.5
265
3 - - 4.5
284
3 - - 37.3
385
2 - - 27.9
320
2 - - 12.6
364
2 - - 0.0
372
2 - - 0.0
358
2 - - 0.0
321
2 - - 8.0
384
2 - - 41.4
291
2 - - 13.5
308
Hsp40
2 - - 41.3
290
2 - - 44.5
317
2 - - 0.0
365
2 - - 9.5
304
2 - - 34.6
377
2 - - 31.9
329
2 - - 0.0
323
2 - - 0.0
296
2 - - 2.2
355
2 - - 0.0
326
AFU_orthologue AFUA_1G03520
2 - - 0.0
305
2 - - 38.1
293
2 - - 0.0
312
2 - - 0.0
299
Hsp40
2 - - 20.3
354
2 - - 0.0
368
2 - - 1.1
289
2 - - 40.9
333
2 - - 0.0
352
2 - - 16.7
378
2 - - 40.5
314
2 - - 1.1
339
2 - - 0.0
341
2 - - 12.0
315
2 - - 0.0
336
2 - - 0.0
302
2 - - 30.0
340
2 - - 3.1
367
2 - - 0.0
331
2 - - 0.0
375
2 - - 0.0
382
2 - - 46.2
330
2 - - 0.0
357
2 - - 6.6
346
2 - - 0.0
362
2 - - 13.3
374
2 - - 0.0
307
2 - - 39.5
343
2 - - 0.0
349
2 - - 0.0
318
2 - - 0.0
292
2 - - 1.4
313
2 - - 0.0
334
2 - - 0.0
348
AFU_orthologue AFUA_5G03040
2 - - 0.0
319
2 - - 1.3
370
2 - - 41.1
322
2 - - 0.0
371
2 - - 0.0
316
2 - - 0.0
335
2 - - 0.0
376
2 - - 0.0
311
2 - - 0.0
345
DnaJ family
2 - - 0.0
310
2 - - 22.8
297
2 - - 13.4
327
2 - - 0.0
379
2 - - 41.6
373
2 - - 0.0
344
2 - - 0.0
338
2 - - 0.0
363
2 - - 8.2
300
2 - - 33.3
342
2 - - 0.0
298
2 - - 15.8
369
2 - - 0.0
301
2 - - 28.9
351
2 - - 42.1
328
2 - - 0.0
366
2 - - 40.4
383
2 - - 46.7
337
2 - - 0.0
350
2 - - 44.5
324
2 - - 1.3
309
2 - - 43.1
361
2 - - 0.0
295
2 - - 0.0
356
2 - - 19.7
347
2 - - 3.9
303
2 - - 31.0
360
2 - - 4.6
332
2 - - 10.1
353
2 - - 0.0
306
Prokaryotic heat shock protein
2 - - 43.2
325
2 - - 0.0
380
2 - - 21.9
381
2 - - 42.9
294
2 - - 1.1
359
2 - - 0.0
395
1 - - 0.0
482
1 - - 0.0
457
Hsp40
1 - - 0.0
430
1 - - 0.0
446
1 - - 0.0
431
1 - - 0.0
475
1 - - 0.0
418
1 - - 0.0
449
1 - - 0.0
394
1 - - 0.0
462
1 - - 0.0
474
1 - - 0.0
443
1 - - 0.0
407
1 - - 0.0
398
1 - - 0.0
388
1 - - 0.0
439
1 - - 0.0
414
1 - - 0.0
433
1 - - 0.0
452
1 - - 0.0
478
1 - - 0.0
415
1 - - 0.0
436
1 - - 0.0
402
1 - - 0.0
440
1 - - 0.0
467
1 - - 0.0
441
1 - - 0.0
397
1 - - 0.0
423
1 - - 0.0
387
1 - - 0.0
455
1 - - 0.0
404
1 - - 0.0
429
1 - - 0.0
477
1 - - 0.0
454
1 - - 0.0
468
1 - - 0.0
426
1 - - 0.0
405
1 - - 0.0
412
1 - - 0.0
464
1 - - 0.0
472
1 - - 0.0
458
1 - - 0.0
421
1 - - 0.0
392
1 - - 0.0
485
1 - - 0.0
420
1 - - 0.0
417
1 - - 0.0
465
1 - - 0.0
484
1 - - 0.0
408
1 - - 0.0
456
1 - - 0.0
403
1 - - 0.0
447
1 - - 0.0
460
1 - - 0.0
424
1 - - 0.0
409
1 - - 0.0
461
1 - - 0.0
481
1 - - 0.0
459
1 - - 0.0
432
1 - - 0.0
453
1 - - 0.0
406
1 - - 0.0
425
1 - - 0.0
480
1 - - 0.0
469
1 - - 0.0
401
1 - - 0.0
463
1 - - 0.0
400
1 - - 0.0
442
1 - - 0.0
466
1 - - 0.0
483
1 - - 0.0
450
1 - - 0.0
437
1 - - 0.0
451
1 - - 0.0
428
1 - - 0.0
445
Hsp40
1 - - 0.0
410
1 - - 0.0
386
1 - - 0.0
396
1 - - 0.0
476
1 - - 0.0
411
1 - - 0.0
473
1 - - 0.0
399
1 - - 0.0
389
1 - - 0.0
438
1 - - 0.0
444
1 - - 0.0
393
1 - - 0.0
479
1 - - 0.0
427
1 - - 0.0
448
1 - - 0.0
419
1 - - 0.0
434
1 - - 0.0
413
1 - - 0.0
390
1 - - 0.0
422
1 - - 0.0
471
1 - - 0.0
416
1 - - 0.0
435
1 - - 0.0
391
1 - - 0.0
470
Prokaryotic heat shock protein
1 - - 0.0
CATH-Gene3D is a Global Biodata Core Resource Learn more...