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CATH Superfamily 1.10.260.40

lambda repressor-like DNA-binding domains

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
lambda repressor-like DNA-binding domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
2
HTH-type transcriptional repressor PurR
1925
3D
 2pugA01 - 93.1
1
POU domain protein
1911
3D
 2xsdC01 - 81.3
3
DNA-binding protein SATB
888
3D
 2o4aA00 - 71.0
4
Cut-like homeobox 1a
837
3D
 1wh8A01 - 76.5
5
One cut domain family member
812
3D
 1s7eA01 - 87.6
6
Transcriptional Regulator BldD
726
3D
 4ob4C00 - 33.7
7
POU domain protein
596
3D
 5wc9F01 - 80.4
8
Fructose repressor
Catabolite repressor/activator
550
3D
 1uxdA00 - 82.4
9
Hepatocyte nuclear factor 1-beta
542
3D
 1ic8B01 - 67.9
10
Cut-like homeobox 1a
489
3D
 1x2lA01 - 82.9
11
homeobox-containing protein 1 isoform X2
477 - - 83.5
12
HTH-type transcriptional regulator GntR
460
3D
 2lcvA00 - 86.8
13
POU domain protein
431
3D
 3d1nP00 - 52.0
14
Cytoskeleton protein RodZ
281 - - 39.8
15
Endothelial differentiation-related factor 1
263
3D
 1x57A00 - 97.8
16
HTH-type transcriptional regulator PuuR
257 - - 66.7
17
DNA-binding transcriptional regulator SfsB
227
3D
 1nerA00 - 54.8
18
Multiprotein bridging factor 1
224 - - 96.5
19
Maltose regulon transcriptional regulator MalI
192 - - 31.2
23
Cyanate hydratase
185
3D
 2ivqJ01 - 4.2
20
Trifunctional nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase/transcriptional regulator NadR
181 - - 49.6
21
Trehalose operon repressor
180 - - 58.3
22
POU domain protein
174 - - 73.7
24
Transcriptional regulator SinR
120
3D
 1b0nA00 - 40.2
25
Cro/Cl family transcriptional regulator
102 - - 64.4
26
Predicted DNA-binding transcriptional regulator
96 - - 9.3
28
Secretion protein EspR
96
3D
 3qyxD00 - 39.1
27
Homeobox protein cut-like
86 - - 75.4
29
XRE family transcriptional regulator
74 - - 40.4
30
Coactivator bridging factor 1
69 - - 74.1
31
DNA-binding transcriptional repressor EbgR
64 - - 0.0
32
Transcriptional regulator ClgR
55
3D
 3f52E00 - 89.6
34
LexA family transcriptional repressor
46
3D
 3bdnB01 - 11.9
33
AnsR family transcriptional regulator
44 - - 2.1
35
Antitoxin MqsA
41 - - 0.0
36
LacI family transcriptional regulator
38 - - 14.9
37
Type II toxin-antitoxin system HigA family antitoxin
37 - - 9.4
38
HTH-type transcriptional regulator hipB
37
3D
 5k98P00 - 10.0
82
S
31
3D
 4j1wC01 - 0.0
39
LacI family transcriptional regulator
29 - - 32.2
40
POU domain, class 6, transcription factor 2
29 - - 6.6
43
DNA-binding protein
26 - - 71.5
41
Asc operon transcriptional repressor
26 - - 14.0
42
LacI family transcriptional regulator
26 - - 20.1
44
Homeobox domain-containing protein
21 - - 29.1
45
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin, putative
20 - - 16.7
46
Cyanate hydratase
18 - - 54.4
47
One cut domain family member
18 - - 97.6
49
XRE family transcriptional regulator
17 - - 22.0
48
DNA-binding helix-turn-helix protein
17 - - 0.0
65
Antitoxin HigA
17
3D
 6chvH01 - 18.8
50
HTH-type transcriptional regulator
16 - - 13.9
51
Probable transcriptional regulator
15 - - 12.5
53
Transcriptional regulator
14 - - 0.0
54
POU domain protein
14 - - 43.5
52
HTH-type transcriptional regulator DicA
14 - - 5.0
56
Transcriptional regulator
13 - - 0.0
59
Transcriptional regulator
13
3D
 4o8bA00 - 1.2
55
XRE family transcriptional regulator
13 - - 3.2
57
XRE family transcriptional regulator
13 - - 0.0
58
Multiprotein-bridging factor 1
12 - - 6.6
60
LacI family DNA-binding transcriptional regulator
11 - - 17.6
61
DNA transposition protein
GpB
9 - - 0.0
62
Predicted transcriptional regulator
8 - - 14.5
63
HTH-type transcriptional regulator prtR
8 - - 0.0
64
Transcriptional repressor RstR
7 - - 0.0
68
Uncharacterized protein
5 - - 53.9
67
Shikimate kinase
5 - - 11.9
66
Homeobox protein cut-like
5 - - 36.6
70
Addiction module antidote protein, HigA family
4 - - 9.1
69
Transcriptional regulator
4 - - 0.0
71
One cut domain family member 2
4 - - 15.3
73
transcription factor protein
3 - - 7.0
72
Helix-turn-helix transcriptional regulator, XRE family
3 - - 0.0
86
Transcription factor protein
2 - - 1.9
85
Uncharacterized protein
2 - - 14.3
83
Transcriptional repressor LexA, putative
2 - - 1.6
79
Virulence-associated protein I
2 - - 0.0
76
Peptidase M23
2 - - 0.0
75
Response regulator receiver
2 - - 11.5
80
Transcriptional regulator of HTH-type, xre family
2 - - 0.0
78
Helix-turn-helix domain protein
2 - - 0.0
81
Helix-turn-helix XRE domain protein
2 - - 0.0
84
Phage repressor-like protein
2 - - 0.0
77
Replication factor C small subunit
2 - - 10.2
74
Homeobox protein cut-like
2 - - 0.0
98
Uncharacterized protein
1 - - 0.0
100
Uncharacterized protein
1 - - 0.0
89
Homeodomain-containing DNA- binding protein, putative
1 - - 0.0
92
HipB protein, putative
1 - - 0.0
97
Octamer-binding transcription factor 3
1 - - 0.0
91
Uncharacterized protein
1 - - 0.0
94
Transcriptional regulator, putative
1 - - 0.0
90
2-hydroxyethylphosphonate dioxygenase
1 - - 0.0
101
Repressor protein cI
1 - - 0.0
87
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
1 - - 0.0
99
Predicted transcriptional regulator, XRE family
1 - - 0.0
96
Uncharacterized protein
1 - - 0.0
95
MBF1 transcription factor
1 - - 0.0
93
Pou4f2
1 - - 0.0
88
Mu phage transposase OrfB TnpB_MuSo2
1 - - 0.0
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