The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Coactivator CBP, KIX domain
".
FunFam 1: E1A binding protein p300
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 108 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Histone acetyltransferase activity GO:0004402
Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
|
12 |
A0A0R4IPF3 (/IDA)
A0A0R4IUG1 (/IDA)
B2RWS6 (/IDA)
M9MS40 (/IDA)
M9PH39 (/IDA)
O01368 (/IDA)
P34545 (/IDA)
P45481 (/IDA)
Q09472 (/IDA)
Q6JHU9 (/IDA)
(2 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
11 |
B2RWS6 (/IPI)
E1B8D6 (/IPI)
F1RK46 (/IPI)
M9MS40 (/IPI)
M9PH39 (/IPI)
O01368 (/IPI)
P45481 (/IPI)
Q09472 (/IPI)
Q6JHU9 (/IPI)
Q92793 (/IPI)
(1 more) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
10 | A0A0G2QC09 (/IPI) B2RWS6 (/IPI) M9MS40 (/IPI) M9PH39 (/IPI) O01368 (/IPI) P34545 (/IPI) P45481 (/IPI) Q09472 (/IPI) Q92793 (/IPI) Q9W321 (/IPI) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
8 | M9MS40 (/IDA) M9PH39 (/IDA) O01368 (/IDA) P45481 (/IDA) Q09472 (/IDA) Q8BJ14 (/IDA) Q92793 (/IDA) Q9W321 (/IDA) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
5 | A0A0G2QC09 (/IGI) M9MS40 (/IGI) M9PH39 (/IGI) O01368 (/IGI) Q9W321 (/IGI) |
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
4 | B2RWS6 (/IDA) P45481 (/IDA) Q09472 (/IDA) Q92793 (/IDA) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
4 | P45481 (/TAS) Q09472 (/TAS) Q6JHU9 (/TAS) Q92793 (/TAS) |
|
Acetyltransferase activity GO:0016407
Catalysis of the transfer of an acetyl group to an acceptor molecule.
|
4 | B2RWS6 (/IDA) P45481 (/IDA) Q09472 (/IDA) Q92793 (/IDA) |
|
Histone acetyltransferase activity (H3-K18 specific) GO:0043993
Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 18) = CoA + histone H3 N6-acetyl-L-lysine (position 18).
|
4 | M9MS40 (/IDA) M9PH39 (/IDA) O01368 (/IDA) Q9W321 (/IDA) |
|
Histone acetyltransferase activity (H3-K27 specific) GO:0044017
Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 27) = CoA + histone H3 N6-acetyl-L-lysine (position 27).
|
4 | M9MS40 (/IDA) M9PH39 (/IDA) O01368 (/IDA) Q9W321 (/IDA) |
Showing 1 to 10 of 108 entries
There are 230 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Histone acetylation GO:0016573
The modification of a histone by the addition of an acetyl group.
|
9 | B2RWS6 (/IDA) M9MS40 (/IDA) M9PH39 (/IDA) O01368 (/IDA) P34545 (/IDA) Q09472 (/IDA) Q6JHU9 (/IDA) Q92793 (/IDA) Q9W321 (/IDA) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
7 | B2RWS6 (/IGI) M9MS40 (/IGI) M9PH39 (/IGI) O01368 (/IGI) P34545 (/IGI) P45481 (/IGI) Q9W321 (/IGI) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
6 | M9MS40 (/IMP) M9PH39 (/IMP) O01368 (/IMP) Q09472 (/IMP) Q6JHU9 (/IMP) Q9W321 (/IMP) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
5 | B2RWS6 (/IDA) P45481 (/IDA) Q09472 (/IDA) Q6JHU9 (/IDA) Q92793 (/IDA) |
|
DNA replication checkpoint GO:0000076
A cell cycle checkpoint that prevents the initiation of nuclear division until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.
|
4 | M9MS40 (/IMP) M9PH39 (/IMP) O01368 (/IMP) Q9W321 (/IMP) |
|
Compound eye morphogenesis GO:0001745
The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
|
4 | M9MS40 (/IMP) M9PH39 (/IMP) O01368 (/IMP) Q9W321 (/IMP) |
|
Heart looping GO:0001947
The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.
|
4 | A0A0R4IPF3 (/IGI) A0A0R4IUG1 (/IGI) F1R259 (/IGI) X1WG57 (/IGI) |
|
Regulation of mitotic nuclear division GO:0007088
Any process that modulates the frequency, rate or extent of mitosis.
|
4 | M9MS40 (/IGI) M9PH39 (/IGI) O01368 (/IGI) Q9W321 (/IGI) |
|
Regulation of mitotic nuclear division GO:0007088
Any process that modulates the frequency, rate or extent of mitosis.
|
4 | M9MS40 (/IMP) M9PH39 (/IMP) O01368 (/IMP) Q9W321 (/IMP) |
|
Neurotransmitter secretion GO:0007269
The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission.
|
4 | M9MS40 (/IMP) M9PH39 (/IMP) O01368 (/IMP) Q9W321 (/IMP) |
Showing 1 to 10 of 230 entries
There are 34 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
13 |
A0A0R4INM9 (/IDA)
A0A0R4IPF2 (/IDA)
A0A2R8Q4T2 (/IDA)
E1B8D6 (/IDA)
M9MS40 (/IDA)
M9PH39 (/IDA)
O01368 (/IDA)
P34545 (/IDA)
P45481 (/IDA)
Q09472 (/IDA)
(3 more) |
|
Histone acetyltransferase complex GO:0000123
A protein complex that possesses histone acetyltransferase activity.
|
6 | B2RWS6 (/IDA) M9MS40 (/IDA) M9PH39 (/IDA) O01368 (/IDA) P45481 (/IDA) Q9W321 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
6 | A0A0G2QC09 (/TAS) B2RWS6 (/TAS) P45481 (/TAS) Q09472 (/TAS) Q6JHU9 (/TAS) Q92793 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
5 | A0A0R4INM9 (/IDA) A0A0R4IPF2 (/IDA) A0A2R8Q4T2 (/IDA) P34545 (/IDA) Q92793 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
4 | M9MS40 (/HDA) M9PH39 (/HDA) O01368 (/HDA) Q9W321 (/HDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
4 | I3L466 (/IDA) I3L466 (/IDA) Q09472 (/IDA) Q92793 (/IDA) |
|
Polytene chromosome GO:0005700
A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible.
|
4 | M9MS40 (/IDA) M9PH39 (/IDA) O01368 (/IDA) Q9W321 (/IDA) |
|
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
|
4 | I3L466 (/IDA) I3L466 (/IDA) Q6JHU9 (/IDA) Q92793 (/IDA) |
|
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
4 | M9MS40 (/IPI) M9PH39 (/IPI) O01368 (/IPI) Q9W321 (/IPI) |
|
Histone methyltransferase complex GO:0035097
A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins.
|
4 | M9MS40 (/IDA) M9PH39 (/IDA) O01368 (/IDA) Q9W321 (/IDA) |
Showing 1 to 10 of 34 entries
