The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"EF-hand
".
FunFam 221: Protein S100-A14 isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | Q9HCY8 (/NAS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q9HCY8 (/IPI) |
Chemokine receptor binding GO:0042379
Interacting selectively and non-covalently with any chemokine receptor.
|
1 | Q9HCY8 (/IMP) |
Chemokine receptor binding GO:0042379
Interacting selectively and non-covalently with any chemokine receptor.
|
1 | Q9D2Q8 (/ISO) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
1 | Q9HCY8 (/IEP) |
Toll-like receptor 4 signaling pathway GO:0034142
Any series of molecular signals generated as a consequence of binding to toll-like receptor 4.
|
1 | Q9HCY8 (/IDA) |
Toll-like receptor 4 signaling pathway GO:0034142
Any series of molecular signals generated as a consequence of binding to toll-like receptor 4.
|
1 | Q9D2Q8 (/ISO) |
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
|
1 | Q9HCY8 (/IEP) |
Calcium ion homeostasis GO:0055074
Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell.
|
1 | Q9HCY8 (/NAS) |
Positive regulation of granulocyte chemotaxis GO:0071624
Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.
|
1 | Q9HCY8 (/IDA) |
Positive regulation of granulocyte chemotaxis GO:0071624
Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.
|
1 | Q9D2Q8 (/ISO) |
Positive regulation of monocyte chemotaxis GO:0090026
Any process that increases the frequency, rate, or extent of monocyte chemotaxis.
|
1 | Q9HCY8 (/IDA) |
Positive regulation of monocyte chemotaxis GO:0090026
Any process that increases the frequency, rate, or extent of monocyte chemotaxis.
|
1 | Q9D2Q8 (/ISO) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9HCY8 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9D2Q8 (/ISO) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9HCY8 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9D2Q8 (/ISO) |
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
|
1 | Q9HCY8 (/IDA) |
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
|
1 | Q9D2Q8 (/ISO) |
Cell junction GO:0030054
A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
|
1 | Q9HCY8 (/IDA) |
Cell junction GO:0030054
A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
|
1 | Q9D2Q8 (/ISO) |
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q9HCY8 (/IDA) |
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q9D2Q8 (/ISO) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q9HCY8 (/HDA) |