The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Histone, subunit A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Histone H2A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 14 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
57 O23628 (/IPI) O23628 (/IPI) O23628 (/IPI) O23628 (/IPI) P0C0S5 (/IPI) P0C0S5 (/IPI) P0C0S5 (/IPI) P0C0S5 (/IPI) P0C0S5 (/IPI) P0C0S5 (/IPI)
(47 more)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
47 P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA)
(37 more)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
47 P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO)
(37 more)
RNA polymerase II core promoter sequence-specific DNA binding GO:0000979
Interacting selectively and non-covalently with a DNA sequence that is part of the core promoter of a RNA polymerase II-transcribed gene.
47 P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA)
(37 more)
RNA polymerase II core promoter sequence-specific DNA binding GO:0000979
Interacting selectively and non-covalently with a DNA sequence that is part of the core promoter of a RNA polymerase II-transcribed gene.
47 P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO)
(37 more)
RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980
Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
47 P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA)
(37 more)
RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980
Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
47 P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO)
(37 more)
Chromatin DNA binding GO:0031490
Interacting selectively and non-covalently with DNA that is assembled into chromatin.
47 P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA)
(37 more)
Chromatin DNA binding GO:0031490
Interacting selectively and non-covalently with DNA that is assembled into chromatin.
47 P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO)
(37 more)
Nucleosomal DNA binding GO:0031492
Interacting selectively and non-covalently with the DNA portion of a nucleosome.
47 P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA)
(37 more)
Nucleosomal DNA binding GO:0031492
Interacting selectively and non-covalently with the DNA portion of a nucleosome.
47 P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO)
(37 more)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
14 O97320 (/IDA) O97320 (/IDA) O97320 (/IDA) O97320 (/IDA) O97320 (/IDA) O97320 (/IDA) O97320 (/IDA) O97320 (/IDA) O97320 (/IDA) O97320 (/IDA)
(4 more)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
5 P08985 (/IDA) P08985 (/IDA) P08985 (/IDA) P08985 (/IDA) P08985 (/IDA)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 P48003 (/ISM)

There are 27 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
47 P0C0S7 (/IDA) P0C0S7 (/IDA) P0C0S7 (/IDA) P0C0S7 (/IDA) P0C0S7 (/IDA) P0C0S7 (/IDA) P0C0S7 (/IDA) P0C0S7 (/IDA) P0C0S7 (/IDA) P0C0S7 (/IDA)
(37 more)
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
47 P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO)
(37 more)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
47 P0C0S5 (/IMP) P0C0S5 (/IMP) P0C0S5 (/IMP) P0C0S5 (/IMP) P0C0S5 (/IMP) P0C0S5 (/IMP) P0C0S5 (/IMP) P0C0S5 (/IMP) P0C0S5 (/IMP) P0C0S5 (/IMP)
(37 more)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
47 P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO)
(37 more)
Cellular response to estradiol stimulus GO:0071392
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
47 P0C0S5 (/IMP) P0C0S5 (/IMP) P0C0S5 (/IMP) P0C0S5 (/IMP) P0C0S5 (/IMP) P0C0S5 (/IMP) P0C0S5 (/IMP) P0C0S5 (/IMP) P0C0S5 (/IMP) P0C0S5 (/IMP)
(37 more)
Cellular response to estradiol stimulus GO:0071392
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
47 P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO)
(37 more)
Chromatin assembly or disassembly GO:0006333
The formation or destruction of chromatin structures.
14 O97320 (/ISS) O97320 (/ISS) O97320 (/ISS) O97320 (/ISS) O97320 (/ISS) O97320 (/ISS) O97320 (/ISS) O97320 (/ISS) O97320 (/ISS) O97320 (/ISS)
(4 more)
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
12 O23628 (/IGI) O23628 (/IGI) O23628 (/IGI) O23628 (/IGI) Q9C944 (/IGI) Q9C944 (/IGI) Q9C944 (/IGI) Q9C944 (/IGI) Q9C944 (/IGI) Q9SII0 (/IGI)
(2 more)
Regulation of DNA methylation GO:0044030
Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.
12 O23628 (/IGI) O23628 (/IGI) O23628 (/IGI) O23628 (/IGI) Q9C944 (/IGI) Q9C944 (/IGI) Q9C944 (/IGI) Q9C944 (/IGI) Q9C944 (/IGI) Q9SII0 (/IGI)
(2 more)
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
9 O23628 (/IGI) O23628 (/IGI) O23628 (/IGI) O23628 (/IGI) Q9C944 (/IGI) Q9C944 (/IGI) Q9C944 (/IGI) Q9C944 (/IGI) Q9C944 (/IGI)
Response to temperature stimulus GO:0009266
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.
5 Q9C944 (/IGI) Q9C944 (/IGI) Q9C944 (/IGI) Q9C944 (/IGI) Q9C944 (/IGI)
Somatic stem cell population maintenance GO:0035019
Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line.
5 P08985 (/IMP) P08985 (/IMP) P08985 (/IMP) P08985 (/IMP) P08985 (/IMP)
Male germ-line stem cell population maintenance GO:0036098
The process by which an organism or tissue maintains a population of male germ-line stem cells.
5 P08985 (/IMP) P08985 (/IMP) P08985 (/IMP) P08985 (/IMP) P08985 (/IMP)
DNA methylation involved in embryo development GO:0043045
The covalent transfer of a methyl group to C-5 of cytosine that contributes to the epigenetic regulation of embryonic gene expression.
5 A0A0R4IPN8 (/IMP) Q0Z946 (/IMP) Q0Z946 (/IMP) Q0Z946 (/IMP) Q7ZU59 (/IMP)
Protein localization to chromatin GO:0071168
Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin.
5 P08985 (/IDA) P08985 (/IDA) P08985 (/IDA) P08985 (/IDA) P08985 (/IDA)
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
4 O23628 (/IDA) O23628 (/IDA) O23628 (/IDA) O23628 (/IDA)
Flower development GO:0009908
The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem.
4 O23628 (/IGI) O23628 (/IGI) O23628 (/IGI) O23628 (/IGI)
Detection of temperature stimulus GO:0016048
The series of events in which a temperature stimulus (hot or cold) is received and converted into a molecular signal.
4 O23628 (/IGI) O23628 (/IGI) O23628 (/IGI) O23628 (/IGI)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
4 O23628 (/IDA) O23628 (/IDA) O23628 (/IDA) O23628 (/IDA)
Negative regulation of cell fate specification GO:0009996
Any process that restricts, stops or prevents a cell from adopting a specific cell fate.
2 Q27511 (/IGI) Q27511 (/IGI)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 Q27511 (/IGI) Q27511 (/IGI)
Chromatin organization GO:0006325
Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin.
1 P48003 (/IMP)
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
1 P48003 (/IPI)
Nucleosome organization GO:0034728
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes.
1 P48003 (/IMP)
Histone exchange GO:0043486
The replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits.
1 P48003 (/IPI)
Positive regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0071931
Any process that activates or increases transcription as part of the G1/S transition of the mitotic cell cycle.
1 P48003 (/IMP)
Negative regulation of CENP-A containing nucleosome assembly GO:1903098
Any process that stops, prevents or reduces the frequency, rate or extent of the formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres.
1 P48003 (/IGI)

There are 20 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
262 P08985 (/IDA) P08985 (/IDA) P08985 (/IDA) P08985 (/IDA) P08985 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA)
(252 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
162 P0C0S5 (/HDA) P0C0S5 (/HDA) P0C0S5 (/HDA) P0C0S5 (/HDA) P0C0S5 (/HDA) P0C0S5 (/HDA) P0C0S5 (/HDA) P0C0S5 (/HDA) P0C0S5 (/HDA) P0C0S5 (/HDA)
(152 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
161 P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO)
(151 more)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
161 P0C0S5 (/HDA) P0C0S5 (/HDA) P0C0S5 (/HDA) P0C0S5 (/HDA) P0C0S5 (/HDA) P0C0S5 (/HDA) P0C0S5 (/HDA) P0C0S5 (/HDA) P0C0S5 (/HDA) P0C0S5 (/HDA)
(151 more)
Nuclear euchromatin GO:0005719
The dispersed less dense form of chromatin in the interphase nucleus. It exists in at least two forms, a some being in the form of transcriptionally active chromatin which is the least condensed, while the rest is inactive euchromatin which is more condensed than active chromatin but less condensed than heterochromatin.
47 P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA)
(37 more)
Nuclear euchromatin GO:0005719
The dispersed less dense form of chromatin in the interphase nucleus. It exists in at least two forms, a some being in the form of transcriptionally active chromatin which is the least condensed, while the rest is inactive euchromatin which is more condensed than active chromatin but less condensed than heterochromatin.
47 P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO)
(37 more)
Nuclear heterochromatin GO:0005720
A condensed form of chromatin, occurring in the nucleus during interphase, that stains strongly with basophilic dyes. The DNA of heterochromatin is typically replicated at a later stage in the cell-division cycle than euchromatin.
47 P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA) P0C0S5 (/IDA)
(37 more)
Nuclear heterochromatin GO:0005720
A condensed form of chromatin, occurring in the nucleus during interphase, that stains strongly with basophilic dyes. The DNA of heterochromatin is typically replicated at a later stage in the cell-division cycle than euchromatin.
47 P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO) P0C0S6 (/ISO)
(37 more)
Nucleosome GO:0000786
A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.
19 O97320 (/IDA) O97320 (/IDA) O97320 (/IDA) O97320 (/IDA) O97320 (/IDA) O97320 (/IDA) O97320 (/IDA) O97320 (/IDA) O97320 (/IDA) O97320 (/IDA)
(9 more)
Chromosome GO:0005694
A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
5 P08985 (/IDA) P08985 (/IDA) P08985 (/IDA) P08985 (/IDA) P08985 (/IDA)
Polytene chromosome GO:0005700
A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible.
5 P08985 (/IDA) P08985 (/IDA) P08985 (/IDA) P08985 (/IDA) P08985 (/IDA)
Polytene chromosome chromocenter GO:0005701
A region at which the centric regions of polytene chromosomes are joined together.
5 P08985 (/IDA) P08985 (/IDA) P08985 (/IDA) P08985 (/IDA) P08985 (/IDA)
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
5 Q9C944 (/IDA) Q9C944 (/IDA) Q9C944 (/IDA) Q9C944 (/IDA) Q9C944 (/IDA)
Site of double-strand break GO:0035861
A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.
5 P08985 (/IDA) P08985 (/IDA) P08985 (/IDA) P08985 (/IDA) P08985 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
3 Q9SII0 (/IDA) Q9SII0 (/IDA) Q9SII0 (/IDA)
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
2 Q27511 (/IDA) Q27511 (/IDA)
Condensed chromosome GO:0000793
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.
2 Q27511 (/IDA) Q27511 (/IDA)
Nuclear nucleosome GO:0000788
A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA in the nucleus into higher order structures.
1 P48003 (/ISM)
Swr1 complex GO:0000812
A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits.
1 P48003 (/IDA)
Ino80 complex GO:0031011
A multisubunit protein complex that contains the Ino80p ATPase; exhibits chromatin remodeling activity and 3' to 5' DNA helicase activity.
1 P48003 (/IDA)
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