The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
c-terminal domain of poly(a) binding protein
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 3: Polyadenylate-binding protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
5 O22173 (/IDA) O22173 (/IDA) P42731 (/IDA) P42731 (/IDA) Q9FXA2 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 O22173 (/IPI) O22173 (/IPI) P42731 (/IPI) P42731 (/IPI) Q9FXA2 (/IPI)
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
2 P42731 (/ISS) P42731 (/ISS)
Poly(A) binding GO:0008143
Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA.
2 Q05196 (/IDA) Q05196 (/IDA)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
3 O22173 (/IEP) O22173 (/IEP) Q9FXA2 (/IEP)
Regulation of nuclear-transcribed mRNA poly(A) tail shortening GO:0060211
Any process that modulates the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.
3 O64380 (/IDA) P42731 (/IDA) P42731 (/IDA)
Nuclear-transcribed mRNA poly(A) tail shortening GO:0000289
Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.
2 Q05196 (/IGI) Q05196 (/IGI)
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
2 Q05196 (/IGI) Q05196 (/IGI)
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
2 P42731 (/ISS) P42731 (/ISS)
Regulation of translational initiation GO:0006446
Any process that modulates the frequency, rate or extent of translational initiation.
2 P42731 (/IDA) P42731 (/IDA)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
2 P42731 (/IEP) P42731 (/IEP)
Regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:1900151
Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.
2 P42731 (/IDA) P42731 (/IDA)
MRNA processing GO:0006397
Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
1 O64380 (/IGI)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
7 O22173 (/IDA) O22173 (/IDA) P42731 (/IDA) P42731 (/IDA) Q05196 (/IDA) Q05196 (/IDA) Q9FXA2 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q05196 (/IDA) Q05196 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...