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CATH Superfamily 1.10.1420.10

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1DNA mismatch repair protein MutSDNA mismatch repair proteinDNA mismatch repair proteinDNA mismatch repair proteinSC:2DNA mismatch repair protein MutSDNA mismatch repair protein Msh3DNA mismatch repair proteinDNA mismatch repair protein MutSDNA mismatch repair protein MutSMutS homolog 5 (E. coli)DNA mismatch repair proteinDNA mismatch repair protein MSH4DNA mismatch repair protein MSH4mutS protein homolog 4DNA mismatch repair proteinDNA mismatch repair protein Msh2mutS protein homolog 4DNA mismatch repair protein Msh2DNA mismatch repair proteinDNA mismatch repair proteinDNA mismatch repair protein MSH2DNA mismatch repair proteinDNA mismatch repair proteinDNA mismatch repair proteinDNA mismatch repair protein msh3DNA mismatch repair protein MSH5DNA mismatch repair proteinDNA mismatch repair proteinDNA mismatch repair protein MSH2DNA mismatch repair protein MSH2DNA mismatch repair protein MSH2DNA mismatch repair protein MSH2Probable DNA mismatch repair protein MSH2DNA mismatch repair protein msh2DNA mismatch repair proteinDNA mismatch repair protein Msh1DNA mismatch repair proteinMsh2pDNA mismatch repair proteinMismatch repair ATPaseMsh2pDNA mismatch repair protein Msh1MutS homolog 4Putative DNA mismatch repair proteinDNA mismatch repair protein Msh6DNA mismatch repair protein Msh1DNA mismatch repair protein MutSDNA mismatch repair protein MutSDNA mismatch repair protein MutSDNA mismatch repair protein Msh5, putativeMsh4pMsh4pUnplaced genomic scaffold supercont1.7, whole genome shotgun sequenceDNA mismatch repair protein Msh2, putativeDNA mismatch repair protein Msh2, putativeMutS homolog 4Mismatch repair proteinMSH (MutS Homolog) familyMutS homolog 3 (E. coli)DNA mismatch repair protein spellchecker 1Putative DNA mismatch repair proteinDNA mismatch repair protein MSH2MutS family proteinDNA mismatch repair protein MutSMutS family proteinDNA mismatch repair protein mutS, putativeUnplaced genomic scaffold supercont2.4, whole genome shotgun sequencePutative mismatch repair protein MSH8Mismatch repair protein MSH3, putativeDNA mismatch repair protein mutS, putativeMismatch repair proteinChromosome 7, whole genome shotgun sequencePutative mismatch repair protein MSH8MutS protein homolog him-14DNA mismatch repair proteinDNA mismatch repair protein MutSDNA mismatch repair protein MSH2DNA mismatch repair proteinDNA mismatch repair protein MutSDNA mismatch repair protein MSH5MutS-like proteinMsh2-like proteinDNA mismatch repair protein Msh4, putativeMutS protein homolog 4MutS protein homolog 4DNA mismatch repair protein Msh4, putativeEndonuclease MutS2Endonuclease MutS2mutS protein homolog 4Predicted proteinDNA mismatch repair proteinDNA mismatch repair protein MSH2, putativeDNA mismatch repair protein MSH2, putativeDNA mismatch repair protein MSH2, putativeDNA mismatch repair proteinMutS homolog, putativeDNA mismatch repair protein MutSMsh2-like proteinDNA mismatch repair proteinEndonuclease MutS2DNA mismatch repair mutS proteinMismatch repair ATPase Msh2Uncharacterized proteinDNA mismatch repair protein Msh3DNA mismatch repair protein Msh2YALI0B10197pDNA mismatch repair protein MutSDNA mismatch repair protein MSH3AaceriAFR603CpDNA mismatch repair protein Msh2DNA mismatch repair protein MutSMuts domain V-domain-containing proteinDNA mismatch repair protein MutS 1DNA mismatch repair protein MutSDNA mismatch repair protein MSH3DNA mismatch repair protein Msh2Uncharacterized proteinDNA mismatch repair protein MSH3DNA mismatch repair protein MutSYALI0B10197pMutS domain V domaincontaining proteinAGAP002642-PAPutative MSH5 proteinUncharacterized proteinDNA mismatch repair protein mutSPredicted proteinPredicted proteinMutS domain III family proteinDNA mismatch repair protein MSH4Dna mismatch repair proteinUncharacterized proteinUncharacterized proteinPutative mis-match repair proteinDNA mismatch repair proteinUncharacterized proteinEndonuclease MutS2DNA mismatch repair proteinMutS domain III proteinAGAP012245-PADNA mismatch repair proteinDNA mismatch repair proteinHim-14Predicted proteinDNA mismatch repair proteinChromosome 23, whole genome shotgun sequencePutative MSH3, mismatch repair ATPaseDNA mismatch repair protein msh3MutS domain III family proteinDNA mismatch repair protein Msh2MSH (MutS Homolog) familyMutS familyMutS domain III family proteinPredicted proteinUncharacterized proteinProtein CBR-MSH-2Uncharacterized proteinUncharacterized proteinUncharacterized proteinMutS domain III family proteinDNA mismatch repair proteinUncharacterized proteinPredicted proteinDNA mismatch repair proteinUncharacterized proteinMutS protein homolog 5MutS protein homolog 5-like ProteinMutS domain III family proteinChromosome 1, whole genome shotgun sequencePutative MSH5, mismatch repair ATPaseGll4003 proteinUncharacterized proteinMismatch repair protein MSH5, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinChromosome 23, whole genome shotgun sequenceDNA mismatch repair mutS proteinDNA Mismatch Repair (MMR) protein MutS, putativeUncharacterized proteinUncharacterized proteinSperm protein, putativeDNA mismatch repair proteinMismatch repair-related protein, putativeMutS domain III family proteinMutS family protein. putativeDNA mismatch repair proteinDNA mismatch repair proteinUncharacterized proteinDNA mismatch repair protein Msh2, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinDNA mismatch repair proteinUncharacterized proteinPredicted proteinDNA mismatch repair proteinMutS homolog 6DNA mismatch repair protein MSH2Uncharacterized proteinUncharacterized proteinOs07g0486000 proteinPredicted proteinUncharacterized proteinDNA mismatch repair proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinDNA mismatch repair proteinUncharacterized protein
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FunFam 105: DNA mismatch repair protein Msh2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
 1 Q553L4 (/ISS)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
 1 Q553L4 (/ISS)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
 1 Q553L4 (/ISS)
Showing 1 to 3 of 3 entries

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
DNA repair GO:0006281
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
 1 Q553L4 (/ISS)
Mismatch repair GO:0006298
A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.
 1 Q553L4 (/ISS)
Postreplication repair GO:0006301
The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication. Includes pathways that remove replication-blocking lesions in conjunction with DNA replication.
 1 Q553L4 (/ISS)
Showing 1 to 3 of 3 entries

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
MutSalpha complex GO:0032301
A heterodimer involved in the recognition and repair of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MSH2 and MSH6.
 1 Q553L4 (/ISS)
MutSbeta complex GO:0032302
A heterodimer involved in binding to and correcting insertion/deletion mutations. In human the complex consists of two subunits, MSH2 and MSH3.
 1 Q553L4 (/ISS)
Showing 1 to 2 of 2 entries
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