CATH Superfamily 1.10.10.2750
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 2: TBC1 domain family member 4
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
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8 | A0A0B4KG76 (/ISS) A0A0B4KGK7 (/ISS) E1JJ52 (/ISS) Q24193 (/ISS) Q6AWQ6 (/ISS) Q8IPP5 (/ISS) Q9TY11 (/ISS) Q9VNG9 (/ISS) |
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
|
8 | A0A0B4KG76 (/IDA) A0A0B4KGK7 (/IDA) E1JJ52 (/IDA) Q24193 (/IDA) Q6AWQ6 (/IDA) Q8IPP5 (/IDA) Q9TY11 (/IDA) Q9VNG9 (/IDA) |
Rab GTPase binding GO:0017137
Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.
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8 | A0A0B4KG76 (/IPI) A0A0B4KGK7 (/IPI) E1JJ52 (/IPI) Q24193 (/IPI) Q6AWQ6 (/IPI) Q8IPP5 (/IPI) Q9TY11 (/IPI) Q9VNG9 (/IPI) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | D3Z881 (/IPI) D3ZGN0 (/IPI) Q8BYJ6 (/IPI) |
There are 11 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cell adhesion mediated by integrin GO:0033627
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.
|
8 | A0A0B4KG76 (/IDA) A0A0B4KGK7 (/IDA) E1JJ52 (/IDA) Q24193 (/IDA) Q6AWQ6 (/IDA) Q8IPP5 (/IDA) Q9TY11 (/IDA) Q9VNG9 (/IDA) |
Regulation of GTPase activity GO:0043087
Any process that modulates the rate of GTP hydrolysis by a GTPase.
|
8 | A0A0B4KG76 (/ISS) A0A0B4KGK7 (/ISS) E1JJ52 (/ISS) Q24193 (/ISS) Q6AWQ6 (/ISS) Q8IPP5 (/ISS) Q9TY11 (/ISS) Q9VNG9 (/ISS) |
Negative regulation of vesicle fusion GO:0031339
Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion.
|
2 | D3Z881 (/IMP) D3ZGN0 (/IMP) |
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
2 | D3Z881 (/IDA) D3ZGN0 (/IDA) |
Vesicle-mediated transport GO:0016192
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
|
1 | O60343 (/IMP) |
Vesicle-mediated transport GO:0016192
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
|
1 | Q8BYJ6 (/ISO) |
Vesicle-mediated transport GO:0016192
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
|
1 | Q8BYJ6 (/ISS) |
Negative regulation of vesicle fusion GO:0031339
Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion.
|
1 | Q8BYJ6 (/ISO) |
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
1 | O60343 (/IMP) |
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
1 | Q8BYJ6 (/ISO) |
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
1 | Q8BYJ6 (/ISS) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
8 | A0A0B4KG76 (/IDA) A0A0B4KGK7 (/IDA) E1JJ52 (/IDA) Q24193 (/IDA) Q6AWQ6 (/IDA) Q8IPP5 (/IDA) Q9TY11 (/IDA) Q9VNG9 (/IDA) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
8 | A0A0B4KG76 (/IDA) A0A0B4KGK7 (/IDA) E1JJ52 (/IDA) Q24193 (/IDA) Q6AWQ6 (/IDA) Q8IPP5 (/IDA) Q9TY11 (/IDA) Q9VNG9 (/IDA) |
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
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2 | D3Z881 (/IDA) D3ZGN0 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
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1 | O60343 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q8BYJ6 (/ISO) |
Cytoplasmic vesicle membrane GO:0030659
The lipid bilayer surrounding a cytoplasmic vesicle.
|
1 | Q8BYJ6 (/TAS) |
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
|
1 | Q8BYJ6 (/ISO) |