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CATH Superfamily 1.10.10.2430

NFRKB winged helix-like domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
NFRKB winged helix-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: NFRKB winged helix-like domain

Structural domains comprising this superfamily share the structure of recently identified winged helix-like domain, found in nuclear factor related to kappa-B-binding (NFRKB) proteins. NFRKB is a component of the metazoan INO80 complex involved in chromatin remodelling, transcription regulation, DNA replication and DNA repair. This winged helix-like domain is however not involved in DNA binding but is instead thought to be involved in protein-protein interactions PMID:22984442.

GO Diversity

Unique GO annotations
8 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
282 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 2
Domain clusters (>95% seq id): 2
Domain clusters (>35% seq id): 1
Unique PDBs: 1
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 5
Function
Unique EC:
Unique GO: 8
Taxonomy
Unique Species: 282
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