The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 86: Holliday junction ATP-dependent DNA helicase RuvB

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA helicase activity GO:0003678
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix.
128 P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA)
(118 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
128 P0A812 (/IPI) P0A812 (/IPI) P0A812 (/IPI) P0A812 (/IPI) P0A812 (/IPI) P0A812 (/IPI) P0A812 (/IPI) P0A812 (/IPI) P0A812 (/IPI) P0A812 (/IPI)
(118 more)
Four-way junction helicase activity GO:0009378
Catalysis of the reaction: ATP + H2O = ADP + phosphate, where this reaction drives the unwinding of the DNA helix of DNA containing four-way junctions, including Holliday junctions.
128 P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA)
(118 more)
Four-way junction helicase activity GO:0009378
Catalysis of the reaction: ATP + H2O = ADP + phosphate, where this reaction drives the unwinding of the DNA helix of DNA containing four-way junctions, including Holliday junctions.
7 Q9KR02 (/ISS) Q9KR02 (/ISS) Q9KR02 (/ISS) Q9KR02 (/ISS) Q9KR02 (/ISS) Q9KR02 (/ISS) Q9KR02 (/ISS)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Recombinational repair GO:0000725
A DNA repair process that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous region of DNA.
128 P0A812 (/IMP) P0A812 (/IMP) P0A812 (/IMP) P0A812 (/IMP) P0A812 (/IMP) P0A812 (/IMP) P0A812 (/IMP) P0A812 (/IMP) P0A812 (/IMP) P0A812 (/IMP)
(118 more)
Response to UV GO:0009411
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
128 P0A812 (/IMP) P0A812 (/IMP) P0A812 (/IMP) P0A812 (/IMP) P0A812 (/IMP) P0A812 (/IMP) P0A812 (/IMP) P0A812 (/IMP) P0A812 (/IMP) P0A812 (/IMP)
(118 more)
SOS response GO:0009432
An error-prone process for repairing damaged microbial DNA.
128 P0A812 (/IEP) P0A812 (/IEP) P0A812 (/IEP) P0A812 (/IEP) P0A812 (/IEP) P0A812 (/IEP) P0A812 (/IEP) P0A812 (/IEP) P0A812 (/IEP) P0A812 (/IEP)
(118 more)
SOS response GO:0009432
An error-prone process for repairing damaged microbial DNA.
128 P0A812 (/RCA) P0A812 (/RCA) P0A812 (/RCA) P0A812 (/RCA) P0A812 (/RCA) P0A812 (/RCA) P0A812 (/RCA) P0A812 (/RCA) P0A812 (/RCA) P0A812 (/RCA)
(118 more)
DNA repair GO:0006281
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
12 Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP)
(2 more)
Cellular response to chromate GO:0071247
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus.
12 Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP)
(2 more)
Cellular response to selenite ion GO:0072715
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus.
12 Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP) Q51426 (/IMP)
(2 more)
DNA recombination GO:0006310
Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
7 Q9KR02 (/ISS) Q9KR02 (/ISS) Q9KR02 (/ISS) Q9KR02 (/ISS) Q9KR02 (/ISS) Q9KR02 (/ISS) Q9KR02 (/ISS)
SOS response GO:0009432
An error-prone process for repairing damaged microbial DNA.
3 Q9A3G8 (/EXP) Q9A3G8 (/EXP) Q9AE09 (/EXP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
128 P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA)
(118 more)
Holliday junction resolvase complex GO:0048476
An endodeoxyribonuclease complex that resolves the 4-way DNA intermediates of a Holliday junction into two separate duplex DNA molecules. Can be branch-migration associated.
128 P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA) P0A812 (/IDA)
(118 more)
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