CATH Superfamily 1.10.10.10
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".
FunFam 50: Cullin 4B
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | D3ZK73 (/IPI) Q13619 (/IPI) Q13619 (/IPI) Q13620 (/IPI) Q3TCH7 (/IPI) Q8LGH4 (/IPI) Q8LGH4 (/IPI) |
|
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
|
1 | Q5BI50 (/IPI) |
Showing 1 to 2 of 2 entries
There are 59 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Ribosome biogenesis GO:0042254
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.
|
5 | A2A432 (/IMP) Q13619 (/IMP) Q13619 (/IMP) Q13620 (/IMP) Q3TCH7 (/IMP) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
4 | Q13619 (/IMP) Q13619 (/IMP) Q13620 (/IMP) Q5BI50 (/IMP) |
|
Nucleotide-excision repair, DNA damage recognition GO:0000715
The identification of lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests the repair complex recognizes distortions in the DNA helix.
|
3 | Q13619 (/TAS) Q13619 (/TAS) Q13620 (/TAS) |
|
Nucleotide-excision repair, DNA duplex unwinding GO:0000717
The unwinding, or local denaturation, of the DNA duplex to create a bubble around the site of the DNA damage.
|
3 | Q13619 (/TAS) Q13619 (/TAS) Q13620 (/TAS) |
|
Transcription-coupled nucleotide-excision repair GO:0006283
The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.
|
3 | Q13619 (/TAS) Q13619 (/TAS) Q13620 (/TAS) |
|
Nucleotide-excision repair, preincision complex stabilization GO:0006293
The stabilization of the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage as well as the unwound DNA. The stabilization of the protein-DNA complex ensures proper positioning of the preincision complex before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.
|
3 | Q13619 (/TAS) Q13619 (/TAS) Q13620 (/TAS) |
|
Nucleotide-excision repair, preincision complex assembly GO:0006294
The aggregation, arrangement and bonding together of proteins on DNA to form the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage. This assembly occurs before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.
|
3 | Q13619 (/TAS) Q13619 (/TAS) Q13620 (/TAS) |
|
Nucleotide-excision repair, DNA incision, 3'-to lesion GO:0006295
The endonucleolytic cleavage of the damaged strand of DNA 3' to the site of damage. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. The incision precedes the incision formed 5' to the site of damage.
|
3 | Q13619 (/TAS) Q13619 (/TAS) Q13620 (/TAS) |
|
Nucleotide-excision repair, DNA incision, 5'-to lesion GO:0006296
The endonucleolytic cleavage of the damaged strand of DNA 5' to the site of damage. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. The incision follows the incision formed 3' to the site of damage.
|
3 | Q13619 (/TAS) Q13619 (/TAS) Q13620 (/TAS) |
|
Nucleotide-excision repair, DNA incision GO:0033683
A process that results in the endonucleolytic cleavage of the damaged strand of DNA. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound.
|
3 | Q13619 (/TAS) Q13619 (/TAS) Q13620 (/TAS) |
Showing 1 to 10 of 59 entries
There are 19 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
16 |
D3ZK73 (/IDA)
K4DI93 (/IDA)
K4DI93 (/IDA)
K4DI93 (/IDA)
K4DI93 (/IDA)
K4DI93 (/IDA)
K4DI93 (/IDA)
K4DI93 (/IDA)
K4DI93 (/IDA)
K4DI93 (/IDA)
(6 more) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
13 |
K4DI93 (/IDA)
K4DI93 (/IDA)
K4DI93 (/IDA)
K4DI93 (/IDA)
K4DI93 (/IDA)
K4DI93 (/IDA)
K4DI93 (/IDA)
K4DI93 (/IDA)
K4DI93 (/IDA)
K4DI93 (/IDA)
(3 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | D3ZK73 (/IDA) Q5BI50 (/IDA) Q8LGH4 (/IDA) Q8LGH4 (/IDA) |
|
Cul4-RING E3 ubiquitin ligase complex GO:0080008
A ubiquitin ligase complex in which a cullin from the Cul4 family and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.
|
4 | Q13619 (/IDA) Q13619 (/IDA) Q13620 (/IDA) Q5BI50 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
3 | Q13619 (/TAS) Q13619 (/TAS) Q13620 (/TAS) |
|
Ubiquitin ligase complex GO:0000151
A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.
|
2 | Q8LGH4 (/IPI) Q8LGH4 (/IPI) |
|
Cul4A-RING E3 ubiquitin ligase complex GO:0031464
A ubiquitin ligase complex in which a cullin from the Cul4A subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.
|
2 | Q13619 (/IDA) Q13619 (/IDA) |
|
Cul4-RING E3 ubiquitin ligase complex GO:0080008
A ubiquitin ligase complex in which a cullin from the Cul4 family and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.
|
2 | Q8LGH4 (/IPI) Q8LGH4 (/IPI) |
|
Cul4-RING E3 ubiquitin ligase complex GO:0080008
A ubiquitin ligase complex in which a cullin from the Cul4 family and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.
|
2 | A2A432 (/ISO) Q3TCH7 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | A2A432 (/ISO) |
Showing 1 to 10 of 19 entries
