The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 447: RNA polymerase sigma factor SigF

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
11 P9WGI3 (/IPI) P9WGI3 (/IPI) P9WGI3 (/IPI) P9WGI3 (/IPI) P9WGI3 (/IPI) P9WGI3 (/IPI) P9WGI3 (/IPI) P9WGI3 (/IPI) P9WGI3 (/IPI) P9WGI3 (/IPI)
(1 more)
Sigma factor activity GO:0016987
Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.
11 P9WGI3 (/IGI) P9WGI3 (/IGI) P9WGI3 (/IGI) P9WGI3 (/IGI) P9WGI3 (/IGI) P9WGI3 (/IGI) P9WGI3 (/IGI) P9WGI3 (/IGI) P9WGI3 (/IGI) P9WGI3 (/IGI)
(1 more)
RNA polymerase core enzyme binding GO:0043175
Interacting selectively and non-covalently with an RNA polymerase core enzyme, containing a specific subunit composition defined as the core enzyme.
11 P9WGI3 (/IDA) P9WGI3 (/IDA) P9WGI3 (/IDA) P9WGI3 (/IDA) P9WGI3 (/IDA) P9WGI3 (/IDA) P9WGI3 (/IDA) P9WGI3 (/IDA) P9WGI3 (/IDA) P9WGI3 (/IDA)
(1 more)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
11 P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP)
(1 more)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
11 P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP)
(1 more)
Cellular response to nitrogen starvation GO:0006995
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nitrogen.
11 P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP)
(1 more)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
11 P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP)
(1 more)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
11 P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP)
(1 more)
Response to anoxia GO:0034059
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.
11 P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP)
(1 more)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
11 P9WGI3 (/IDA) P9WGI3 (/IDA) P9WGI3 (/IDA) P9WGI3 (/IDA) P9WGI3 (/IDA) P9WGI3 (/IDA) P9WGI3 (/IDA) P9WGI3 (/IDA) P9WGI3 (/IDA) P9WGI3 (/IDA)
(1 more)
Response to antibiotic GO:0046677
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
11 P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP) P9WGI3 (/IMP)
(1 more)
Cellular response to cold GO:0070417
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
11 P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP) P9WGI3 (/IEP)
(1 more)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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