The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 249: Transcriptional regulator, LysR family

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
47 P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA)
(37 more)
Bacterial-type RNA polymerase regulatory region DNA binding GO:0001017
Interacting selectively and non-covalently with a DNA region that controls the transcription of a gene or operon by a bacterial-type RNA polymerase. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
47 P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA)
(37 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
47 P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA)
(37 more)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
47 P39376 (/ISS) P39376 (/ISS) P39376 (/ISS) P39376 (/ISS) P39376 (/ISS) P39376 (/ISS) P39376 (/ISS) P39376 (/ISS) P39376 (/ISS) P39376 (/ISS)
(37 more)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
47 P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA) P39376 (/IDA)
(37 more)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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