The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 224: RNA polymerase sigma factor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sigma factor activity GO:0016987
Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.
136 A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS)
(126 more)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-templated transcription, initiation GO:0006352
Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription.
136 A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS)
(126 more)
Asexual sporulation GO:0030436
The formation of spores derived from the products of an asexual cell division. Examples of this process are found in bacteria and fungi.
136 A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS) A0A1Q4M6U4 (/ISS)
(126 more)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
CATH-Gene3D is a Global Biodata Core Resource Learn more...