The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 164: Transcriptional regulator, Rrf2 family

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Core promoter binding GO:0001047
Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
16 O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA)
(6 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
16 O34527 (/IPI) O34527 (/IPI) O34527 (/IPI) O34527 (/IPI) O34527 (/IPI) O34527 (/IPI) O34527 (/IPI) O34527 (/IPI) O34527 (/IPI) O34527 (/IPI)
(6 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
16 O34527 (/IPI) O34527 (/IPI) O34527 (/IPI) O34527 (/IPI) O34527 (/IPI) O34527 (/IPI) O34527 (/IPI) O34527 (/IPI) O34527 (/IPI) O34527 (/IPI)
(6 more)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
16 O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA)
(6 more)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
16 O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA)
(6 more)
Protein heterooligomerization GO:0051291
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
16 O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA)
(6 more)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
16 O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA)
(6 more)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
16 O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA) O34527 (/IDA)
(6 more)
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