CATH Superfamily 1.10.10.10
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".
FunFam 158: La ribonucleoprotein domain family member 7
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 21 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
14 |
F1QDH4 (/IDA)
P33399 (/IDA)
P33399 (/IDA)
P33399 (/IDA)
P33399 (/IDA)
P33399 (/IDA)
P33399 (/IDA)
P33399 (/IDA)
Q38C07 (/IDA)
Q38C07 (/IDA)
(4 more) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
11 |
P33399 (/IPI)
P33399 (/IPI)
P33399 (/IPI)
P33399 (/IPI)
P33399 (/IPI)
P33399 (/IPI)
P33399 (/IPI)
Q4G0J3 (/IPI)
Q8BN59 (/IPI)
Q9BRS8 (/IPI)
(1 more) |
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
|
8 | P33399 (/IDA) P33399 (/IDA) P33399 (/IDA) P33399 (/IDA) P33399 (/IDA) P33399 (/IDA) P33399 (/IDA) P87058 (/IDA) |
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
6 | O80567 (/IDA) Q38C07 (/IDA) Q38C07 (/IDA) Q9N9G6 (/IDA) Q9N9G6 (/IDA) Q9NIH4 (/IDA) |
Myosin binding GO:0017022
Interacting selectively and non-covalently with any part of a myosin complex; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments.
|
2 | Q9BRS8 (/IPI) Q9BRS8 (/IPI) |
RNA stem-loop binding GO:0035613
Interacting selectively and non-covalently with a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.
|
2 | Q9BRS8 (/IDA) Q9BRS8 (/IDA) |
RNA stem-loop binding GO:0035613
Interacting selectively and non-covalently with a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.
|
2 | Q9BRS8 (/IMP) Q9BRS8 (/IMP) |
MRNA 5'-UTR binding GO:0048027
Interacting selectively and non-covalently with the 5' untranslated region of an mRNA molecule.
|
2 | Q9BRS8 (/IDA) Q9BRS8 (/IDA) |
MRNA 5'-UTR binding GO:0048027
Interacting selectively and non-covalently with the 5' untranslated region of an mRNA molecule.
|
2 | Q9BRS8 (/IMP) Q9BRS8 (/IMP) |
Sequence-specific mRNA binding GO:1990825
Interacting selectively and non-covalently with messenger RNA (mRNA) of a specific nucleotide composition or a specific sequence motif.
|
2 | Q9BRS8 (/IDA) Q9BRS8 (/IDA) |
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
|
1 | P87058 (/IMP) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q4G0J3 (/HDA) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q4QCG1 (/ISO) |
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
1 | Q4QCG1 (/ISO) |
Myosin binding GO:0017022
Interacting selectively and non-covalently with any part of a myosin complex; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments.
|
1 | Q8BN59 (/ISO) |
RNA strand annealing activity GO:0033592
Facilitates the base-pairing of complementary single-stranded RNA.
|
1 | P87058 (/IDA) |
RNA stem-loop binding GO:0035613
Interacting selectively and non-covalently with a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.
|
1 | Q8BN59 (/ISO) |
MRNA 5'-UTR binding GO:0048027
Interacting selectively and non-covalently with the 5' untranslated region of an mRNA molecule.
|
1 | Q8BN59 (/ISO) |
MRNA 5'-UTR binding GO:0048027
Interacting selectively and non-covalently with the 5' untranslated region of an mRNA molecule.
|
1 | Q8BN59 (/ISS) |
Sequence-specific mRNA binding GO:1990825
Interacting selectively and non-covalently with messenger RNA (mRNA) of a specific nucleotide composition or a specific sequence motif.
|
1 | Q8BN59 (/ISO) |
Sequence-specific mRNA binding GO:1990825
Interacting selectively and non-covalently with messenger RNA (mRNA) of a specific nucleotide composition or a specific sequence motif.
|
1 | Q8BN59 (/ISS) |
There are 24 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
TRNA processing GO:0008033
The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.
|
8 | P33399 (/IMP) P33399 (/IMP) P33399 (/IMP) P33399 (/IMP) P33399 (/IMP) P33399 (/IMP) P33399 (/IMP) P87058 (/IMP) |
RNA processing GO:0006396
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
|
6 | Q38C07 (/ISM) Q38C07 (/ISM) Q4QCG1 (/ISM) Q9N9G6 (/ISM) Q9N9G6 (/ISM) Q9NIH4 (/ISM) |
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
|
2 | F1QDH4 (/IMP) Q6PHD4 (/IMP) |
Positive regulation of collagen biosynthetic process GO:0032967
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
|
2 | Q9BRS8 (/IMP) Q9BRS8 (/IMP) |
Positive regulation of translation GO:0045727
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
|
2 | Q9BRS8 (/IMP) Q9BRS8 (/IMP) |
Positive regulation of mRNA binding GO:1902416
Any process that activates or increases the frequency, rate or extent of mRNA binding.
|
2 | Q9BRS8 (/IDA) Q9BRS8 (/IDA) |
Positive regulation of mRNA binding GO:1902416
Any process that activates or increases the frequency, rate or extent of mRNA binding.
|
2 | Q9BRS8 (/IMP) Q9BRS8 (/IMP) |
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | Q05CL8 (/IGI) |
TRNA 5'-leader removal GO:0001682
Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P.
|
1 | P87058 (/IMP) |
Termination of RNA polymerase III transcription GO:0006386
The process in which transcription by RNA polymerase III is terminated; Pol III has an intrinsic ability to terminate transcription upon incorporation of 4 to 6 contiguous U residues.
|
1 | P87058 (/TAS) |
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | A1Z9R1 (/IMP) |
Positive regulation of collagen biosynthetic process GO:0032967
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
|
1 | Q8BN59 (/ISO) |
TRNA 3'-trailer cleavage, endonucleolytic GO:0034414
Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA.
|
1 | P87058 (/IMP) |
Negative regulation of chromatin binding GO:0035562
Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
1 | Q05CL8 (/IGI) |
Germ cell proliferation GO:0036093
The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population.
|
1 | Q05CL8 (/IMP) |
TRNA 3'-trailer cleavage GO:0042779
Cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA; may involve endonucleolytic or exonucleolytic cleavage, or both.
|
1 | P87058 (/IGI) |
TRNA 3'-end processing GO:0042780
The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA.
|
1 | P87058 (/IMP) |
Positive regulation of translation GO:0045727
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
|
1 | Q8BN59 (/ISO) |
Regulation of cardiac muscle cell proliferation GO:0060043
Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation.
|
1 | Q7ZWE3 (/IGI) |
Cardiac muscle tissue regeneration GO:0061026
The regrowth of cardiac muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.
|
1 | Q7ZWE3 (/IGI) |
TRNA folding GO:0061818
The process of assisting in the folding of tRNAs into the correct tertiary structure.
|
1 | P87058 (/IMP) |
Positive regulation of G1/S transition of mitotic cell cycle GO:1900087
Any signalling pathway that increases or activates a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.
|
1 | Q05CL8 (/IMP) |
Positive regulation of mRNA binding GO:1902416
Any process that activates or increases the frequency, rate or extent of mRNA binding.
|
1 | Q8BN59 (/ISO) |
Positive regulation of mRNA binding GO:1902416
Any process that activates or increases the frequency, rate or extent of mRNA binding.
|
1 | Q8BN59 (/ISS) |
There are 17 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
17 |
D6RAF3 (/IDA)
D6RF49 (/IDA)
D6RF49 (/IDA)
D6RFF0 (/IDA)
P33399 (/IDA)
P33399 (/IDA)
P33399 (/IDA)
P33399 (/IDA)
P33399 (/IDA)
P33399 (/IDA)
(7 more) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
10 | P33399 (/IDA) P33399 (/IDA) P33399 (/IDA) P33399 (/IDA) P33399 (/IDA) P33399 (/IDA) P33399 (/IDA) P87058 (/IDA) Q9BRS8 (/IDA) Q9BRS8 (/IDA) |
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
7 | P33399 (/IDA) P33399 (/IDA) P33399 (/IDA) P33399 (/IDA) P33399 (/IDA) P33399 (/IDA) P33399 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | D6RAF3 (/IDA) D6RF49 (/IDA) D6RF49 (/IDA) D6RFF0 (/IDA) Q4G0J3 (/IDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | Q05CL8 (/ISO) Q4QCG1 (/ISO) |
Polysome GO:0005844
A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.
|
2 | Q9BRS8 (/IDA) Q9BRS8 (/IDA) |
Polysome GO:0005844
A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.
|
2 | Q9BRS8 (/IMP) Q9BRS8 (/IMP) |
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
|
2 | Q9BRS8 (/IDA) Q9BRS8 (/IDA) |
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
|
2 | Q9BRS8 (/IMP) Q9BRS8 (/IMP) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P87058 (/HDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q8BN59 (/ISO) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P87058 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q05CL8 (/ISO) |
Polysome GO:0005844
A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.
|
1 | Q8BN59 (/ISO) |
Polysome GO:0005844
A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.
|
1 | Q8BN59 (/ISS) |
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
|
1 | Q8BN59 (/ISO) |
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
|
1 | Q8BN59 (/ISS) |