CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin kappa chain variable 12-38

Enzyme Information

UniProtKB Entries (1)

O75084
FZD7_HUMAN
Homo sapiens
Frizzled-7

PDB Structure

PDB 6O3A
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies.
Raman, S., Beilschmidt, M., To, M., Lin, K., Lui, F., Jmeian, Y., Ng, M., Fernandez, M., Fu, Y., Mascall, K., Duque, A., Wang, X., Pan, G., Angers, S., Moffat, J., Sidhu, S.S., Magram, J., Sinclair, A.M., Fransson, J., Julien, J.P.
Proc. Natl. Acad. Sci. U.S.A.
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